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Stochastic optimization of the Area Under the Precision-Recall Curve (AUPRC) is a crucial problem for machine learning. Although various algorithms have been extensively studied for AUPRC optimization, the generalization is only guaranteed…

Machine Learning · Computer Science 2022-09-28 Peisong Wen , Qianqian Xu , Zhiyong Yang , Yuan He , Qingming Huang

While there has been a growing research interest in developing out-of-distribution (OOD) detection methods, there has been comparably little discussion around how these methods should be evaluated. Given their relevance for safe(r) AI, it…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Galadrielle Humblot-Renaux , Sergio Escalera , Thomas B. Moeslund

Academic advances of AI models in high-precision domains, like healthcare, need to be made explainable in order to enhance real-world adoption. Our past studies and ongoing interactions indicate that medical experts can use AI systems with…

Adversarial attack perturbs an image with an imperceptible noise, leading to incorrect model prediction. Recently, a few works showed inherent bias associated with such attack (robustness bias), where certain subgroups in a dataset (e.g.…

Computer Vision and Pattern Recognition · Computer Science 2022-05-06 Gaurav Kumar Nayak , Ruchit Rawal , Rohit Lal , Himanshu Patil , Anirban Chakraborty

The use of AI systems in healthcare for the early screening of diseases is of great clinical importance. Deep learning has shown great promise in medical imaging, but the reliability and trustworthiness of AI systems limit their deployment…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Ke Zou , Zhihao Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

This paper demonstrates a methodology for examining the accuracy of uncertain inference systems (UIS), after their parameters have been optimized, and does so for several common UIS's. This methodology may be used to test the accuracy when…

Artificial Intelligence · Computer Science 2013-04-11 Ben P. Wise

Reliable uncertainty quantification in deep neural networks is very crucial in safety-critical applications such as automated driving for trustworthy and informed decision-making. Assessing the quality of uncertainty estimates is…

Computer Vision and Pattern Recognition · Computer Science 2022-12-12 Neslihan Kose , Ranganath Krishnan , Akash Dhamasia , Omesh Tickoo , Michael Paulitsch

In medical imaging, inter-observer variability among radiologists often introduces label uncertainty, particularly in modalities where visual interpretation is subjective. Lung ultrasound (LUS) is a prime example-it frequently presents a…

Evaluation of clinical prediction models across multiple clusters, whether centers or datasets, is becoming increasingly common. A comprehensive evaluation includes an assessment of the agreement between the estimated risks and the observed…

Methodology · Statistics 2026-04-22 Lasai Barreñada , Bavo D. C. Campo , Laure Wynants , Ben Van Calster

The importance of uncertainty quantification is increasingly recognized in the diverse field of machine learning. Accurately assessing model prediction uncertainty can help provide deeper understanding and confidence for researchers and…

Machine Learning · Computer Science 2024-12-03 Tianyi Chen , Yingzhou Lu , Nan Hao , Yuanyuan Zhang , Capucine Van Rechem , Jintai Chen , Tianfan Fu

Several variants of reweighted risk functionals, such as focal loss, inverse focal loss, and the Area Under the Risk Coverage Curve (AURC), have been proposed for improving model calibration; yet their theoretical connections to calibration…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Han Zhou , Sebastian G. Gruber , Teodora Popordanoska , Matthew B. Blaschko

Epistemic Uncertainty is a measure of the lack of knowledge of a learner which diminishes with more evidence. While existing work focuses on using the variance of the Bayesian posterior due to parameter uncertainty as a measure of epistemic…

The positive-unlabeled (PU) classification is a common scenario in real-world applications such as healthcare, text classification, and bioinformatics, in which we only observe a few samples labeled as "positive" together with a large…

Machine Learning · Computer Science 2018-03-20 Ke Ren , Haichuan Yang , Yu Zhao , Mingshan Xue , Hongyu Miao , Shuai Huang , Ji Liu

Effective representation learning is the key in improving model performance for medical image analysis. In training deep learning models, a compromise often must be made between performance and trust, both of which are essential for medical…

Machine Learning · Computer Science 2021-12-17 Siyuan He , Pengcheng Xi , Ashkan Ebadi , Stephane Tremblay , Alexander Wong

The area under a receiver operating characteristic curve (AUC) is a useful tool to assess the performance of continuous-scale diagnostic tests on binary classification. In this article, we propose an empirical likelihood (EL) method to…

Methodology · Statistics 2022-05-05 Chul Moon , Xinlei Wang , Johan Lim

Deep learning models often achieve expert-level accuracy in medical image classification but suffer from a critical flaw: semantic incoherence. These high-confidence mistakes that are semantically incoherent (e.g., classifying a malignant…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Abolfazl Mohammadi-Seif , Ricardo Baeza-Yates

Uncertainty of labels in clinical data resulting from intra-observer variability can have direct impact on the reliability of assessments made by deep neural networks. In this paper, we propose a method for modelling such uncertainty in the…

In medical diagnostics, leveraging multiple biomarkers can significantly improve classification accuracy compared to using a single biomarker. While existing methods based on exponential tilting or density ratio models have shown promise,…

Methodology · Statistics 2026-01-08 Fangyong Zheng , Pengfei Li , Tao Yu

While modern deep neural networks are performant perception modules, performance (accuracy) alone is insufficient, particularly for safety-critical robotic applications such as self-driving vehicles. Robot autonomy stacks also require these…

Computer Vision and Pattern Recognition · Computer Science 2021-09-29 Dhaivat Bhatt , Kaustubh Mani , Dishank Bansal , Krishna Murthy , Hanju Lee , Liam Paull

The classification of imbalanced data has presented a significant challenge for most well-known classification algorithms that were often designed for data with relatively balanced class distributions. Nevertheless skewed class distribution…

Machine Learning · Statistics 2023-04-21 Jiaju Miao , Wei Zhu
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