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Nuclear magnetic resonance (NMR) is a powerful method for determining the structure of molecules and proteins. While conventional NMR requires averaging over large ensembles, recent progress with single-spin quantum sensors has created the…

Optically active spin defects in solids offer promising platforms to investigate nuclear spin clusters with high sensitivity and atomic-site resolution. To leverage near-surface defects for molecular structure analysis in chemical and…

Nuclear spin imaging at the atomic level is essential for the understanding of fundamental biological phenomena and for applications such as drug discovery. The advent of novel nano-scale sensors has given hope of achieving the…

Quantum Physics · Physics 2015-11-25 Ashok Ajoy , Ulf Bissbort , Mikhail D. Lukin , Ronald L. Walsworth , Paola Cappellaro

Magnetic spin resonance is a key non-invasive sensing and imaging technique across the life-, material- and fundamental sciences with further medical and commercial applications. Recent advances using paramagnetic color centers enable…

Mesoscale and Nanoscale Physics · Physics 2018-07-24 Florestan Ziem , Marwa Garsi , Helmut Fedder , Jörg Wrachtrup

Magnetic resonance imaging, based on the manipulation and detection of nuclear spins, is a powerful imaging technique that typically operates on the scale of millimeters to microns. Using magnetic resonance force microscopy, we have…

Other Condensed Matter · Physics 2007-06-27 H. J. Mamin , M. Poggio , C. L. Degen , D. Rugar

Nuclear magnetic resonance spectroscopy with solid-state spin sensors is a promising pathway for the detection of nuclear spins at the micro- and nanoscale. Although many nanoscale experiments rely on a single sensor spin for the detection…

Sensing single nuclear spins is a central challenge in magnetic resonance based imaging techniques. Although different methods and especially diamond defect based sensing and imaging techniques in principle have shown sufficient…

Nuclear magnetic resonance (NMR) spectroscopy is a powerful technique for analyzing the structure and function of molecules, and for performing three-dimensional imaging of the spin density. At the heart of NMR spectrometers is the…

Quantum Physics · Physics 2019-04-15 K. S. Cujia , J. M. Boss , K. Herb , J. Zopes , C. L. Degen

Single-molecule nuclear magnetic resonance (NMR) is a crown-jewel challenge in the field of magnetic resonance spectroscopy and has important applications in chemical analysis and in quantum computing. Recently, it becomes possible to…

Mesoscale and Nanoscale Physics · Physics 2015-06-17 Fazhan Shi , Xi Kong , Pengfei Wang , Fei Kong , Nan Zhao , Ren-Bao Liu , Jiangfeng Du

The detection of nuclear spins using individual electron spins has enabled new opportunities in quantum sensing and quantum information processing. Proof-of-principle experiments have demonstrated atomic-scale imaging of nuclear-spin…

Magnetic Resonance Imaging (MRI) can characterize and discriminate among tissues using their diverse physical and biochemical properties. Unfortunately, submicrometer screening of biological specimens is presently not possible, mainly due…

Mesoscale and Nanoscale Physics · Physics 2010-11-03 C. A. Meriles , L. Jiang , G. Goldstein , J. S. Hodges , J. R. Maze , M. D. Lukin , P. Cappellaro

Efficiently detecting and characterizing individual spins in solid-state hosts is an essential step to expand the fields of quantum sensing and quantum information processing. While selective detection and control of a few 13C nuclear spins…

Quantum Physics · Physics 2020-10-22 Hyunseok Oh , Jiwon Yun , M. H. Abobeih , Kyung-Hoon Jung , Kiho Kim , T. H. Taminiau , Dohun Kim

Distance measurements via the dipolar interaction are fundamental to the application of nuclear magnetic resonance (NMR) to molecular structure determination, but they only provide information on the absolute distance $r$ and polar angle…

Quantum Physics · Physics 2018-10-30 J. Zopes , K. Herb , K. S. Cujia , C. L. Degen

Two-dimensional Nuclear Magnetic Resonance (NMR) is essential in molecular structure determination. The Nitrogen-Vacancy (NV) center in diamond has been proposed and developed as an outstanding quantum sensor to realize NMR in nanoscale. In…

We report on precise localization spectroscopy experiments of individual 13C nuclear spins near a central electronic sensor spin in a diamond chip. By detecting the nuclear free precession signals in rapidly switchable external magnetic…

Quantum Physics · Physics 2018-12-10 J. Zopes , K. S. Cujia , K. Sasaki , J. M. Boss , K. M. Itoh , C. L. Degen

We perform sensitive nuclear magnetic resonance (NMR) with spin ensembles which are polarized by nitrogen vacancy centers (NV centers) in diamond at room-temperature. With a near shot-noise-limited photoluminescence detection and a highly…

Nuclear magnetic resonance (NMR) is a powerful tool for applications ranging from chemical analysis to quantum information processing. Achieving optical initialization and detection of molecular nuclear spins promises new opportunities -…

Single-molecule sensitivity of nuclear magnetic resonance (NMR) and angstrom resolution of magnetic resonance imaging (MRI) are the highest challenges in magnetic microscopy. Recent development in dynamical-decoupling- (DD) enhanced diamond…

Quantum Physics · Physics 2016-08-31 Wen-Long Ma , Ren-Bao Liu

Magnetic resonance imaging (MRI) has revolutionized biomedical science by providing non-invasive, three-dimensional biological imaging. However, spatial resolution in conventional MRI systems is limited to tens of microns, which is…

Mesoscale and Nanoscale Physics · Physics 2015-06-18 M. S. Grinolds , M. Warner , K. De Greve , Y. Dovzhenko , L. Thiel , R. L. Walsworth , S. Hong , P. Maletinsky , A. Yacoby

Achieving atomic resolution is the ultimate limit of magnetic resonance imaging (MRI), and attaining this capability offers enormous technological and scientific opportunities, from drug development to understanding the dynamics in…

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