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Related papers: Targeted Vaccination Strategies for an Infinite-di…

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In this paper we introduce an approach to the management of infectious disease diffusion through the formulation of a controlled compartmental SVIR (Susceptible-Vaccinated-Infected-Recovered) model. We consider a cost functional…

Optimization and Control · Mathematics 2023-11-28 Alessandro Ramponiand M. Elisabetta Tessitore

In this paper we investigate the asymptotic behavior of some SIR models incorporating demography, bounded random transmission coefficient and a time-dependent vaccination strategy targeting the susceptible population. In this setting, we…

Populations and Evolution · Quantitative Biology 2025-10-27 Javier López-de-la-Cruz , Susana Merchán , Felipe Rivero , Javier Rodrigo

In the context of SARS-CoV-2 pandemic, mathematical modelling has played a fundamental role for making forecasts, simulating scenarios and evaluating the impact of preventive political, social and pharmaceutical measures. Optimal control…

Optimization and Control · Mathematics 2022-11-01 Giovanni Ziarelli , Luca Dede' , Nicola Parolini , Marco Verani , Alfio Quarteroni

We study how a fraction of a population should be vaccinated to most efficiently top epidemics. We argue that only local information (about the neighborhood of specific vertices) is usable in practice, and hence we consider only local…

Populations and Evolution · Quantitative Biology 2007-05-23 Petter Holme

In this paper, we extend the classical SIRS (Susceptible-Infectious-Recovered-Susceptible) model from mathematical epidemiology by incorporating a vaccinated compartment, V, accounting for an imperfect vaccine with waning efficacy over…

Populations and Evolution · Quantitative Biology 2025-01-30 Joseph Páez Chávez , Aytül Gökçe , Thomas Götz , Burcu Gürbüz

The pandemic caused by the SARS-CoV-2 virus has exposed many flaws in the decision-making strategies used to distribute resources to combat global health crises. In this paper, we leverage reinforcement learning and optimization to improve…

Artificial Intelligence · Computer Science 2021-01-06 Lawrence Thul , Warren Powell

We study three different strategies of vaccination in a SEIRS (Susceptible--Exposed--Infected--Recovered--Susceptible) seasonal forced model, which are: ($i$) continuous vaccination; ($ii$) periodic short time localized vaccination and…

Individual-based epidemiological models support the study of fine-grained preventive measures, such as tailored vaccine allocation policies, in silico. As individual-based models are computationally intensive, it is pivotal to identify…

Machine Learning · Computer Science 2025-02-27 Alexandra Cimpean , Timothy Verstraeten , Lander Willem , Niel Hens , Ann Nowé , Pieter Libin

Since the recent introduction of several viable vaccines for SARS-CoV-2, vaccination uptake has become the key factor that will determine our success in containing the COVID-19 pandemic. We argue that game theory and social network models…

In this paper we consider SIR epidemics on random graphs with clustering. To incorporate group structure of the underlying social network, we use a generalized version of the configuration model in which each node is a member of a specified…

Probability · Mathematics 2018-02-15 Carolina Fransson , Pieter Trapman

Vaccination campaigns have saved thousands of lives, reaching the farthest places in the world. These campaigns have required substantial investments and accurate coordination between several actors within the vaccine supply chain. Despite…

Early on during a pandemic, vaccine availability is limited, requiring prioritisation of different population groups. Evaluating vaccine allocation is therefore a crucial element of pandemics response. In the present work, we develop a…

Vaccination has been proven to be the most effective method to prevent infectious diseases. However, in many low and middle-income countries with geographically dispersed and nomadic populations, last-mile vaccine delivery can be extremely…

Applications · Statistics 2021-04-30 Yuwen Yang , Jayant Rajgopal

Here, we consider an SIS epidemic model where the individuals are distributed on several distinct patches. We construct a stochastic model and then prove that it converges to a deterministic model as the total population size tends to…

Probability · Mathematics 2020-07-16 T. Yeo

This paper is concerned with the analysis of vaccination strategies in a stochastic SIR (susceptible $\to$ infected $\to$ removed) model for the spread of an epidemic amongst a population of individuals with a random network of social…

Physics and Society · Physics 2016-11-16 Frank Ball , David Sirl

Covid-19 has caused hundred of thousands of deaths and an economic damage amounting to trillions of dollars, creating a desire for the rapid development of vaccine. Once available, vaccine is gradually produced, evoking the question on how…

Populations and Evolution · Quantitative Biology 2020-06-30 Jens Grauer , Hartmut Löwen , Benno Liebchen

There are often multiple diseases with cross immunity competing for vaccination resources. Here we investigate the optimal vaccination program in a two-layer Susceptible-Infected-Removed (SIR) model, where two diseases with cross immunity…

Populations and Evolution · Quantitative Biology 2021-05-26 Yang Ye , Qingpeng Zhang , Zhidong Cao , Daniel Dajun Zeng

We consider an infinite-dimension SIS model introduced by Delmas, Dronnier and Zitt, with a more general incidence rate, and study its equilibria. Unsurprisingly, there exists at least one endemic equilibrium if and only if the basic…

Analysis of PDEs · Mathematics 2026-02-04 Jean-François Delmas , Kacem Lefki , Pierre-André Zitt

In this paper, we investigate game-theoretic strategies for containing spreading processes on large-scale networks. Specifically, we consider the class of networked susceptible-infected-susceptible (SIS) epidemics where a large population…

Systems and Control · Electrical Eng. & Systems 2024-07-04 Abhisek Satapathi , Ashish R. Hota

This study explores the vaccine prioritization strategy to reduce the overall burden of the pandemic when the supply is limited. Existing methods conduct macro-level or simplified micro-level vaccine distribution by assuming the homogeneous…

Populations and Evolution · Quantitative Biology 2023-05-10 Lu Ling , Washim Uddin Mondal , Satish V , Ukkusuri