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Related papers: Targeted Vaccination Strategies for an Infinite-di…

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In this article, we introduce an infinite-dimensional deterministic SIS model which takes into account the heterogeneity of the infections and the social network among a large population. We study the long-time behavior of the dynamic. We…

Dynamical Systems · Mathematics 2020-06-16 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

How to allocate vaccines over heterogeneous individuals is one of the important policy decisions in pandemic times. This paper develops a procedure to estimate an individualized vaccine allocation policy under limited supply, exploiting…

Econometrics · Economics 2021-10-25 Toru Kitagawa , Guanyi Wang

We consider a SIR model with temporary immunity and time dependent transmission rate. We assume time dependent vaccination which confers the same immunity as natural infection. We study two types of vaccination strategies: i) optimal…

Populations and Evolution · Quantitative Biology 2016-04-06 Paulo Doutor , Paula Rodrigues , Maria do Céu Soares , Fabio A. C. C. Chalub

We consider the problem of the optimal allocation of vaccination and protection measures for the Susceptible-Infected-Recovered-Infected (SIRI) epidemiological model, which generalizes the classical Susceptible-Infected-Recovered (SIR) and…

Optimization and Control · Mathematics 2025-05-09 Urmee Maitra , Ashish R. Hota , Rohit Gupta , Alfred O. Hero

This paper studies an optimal control problem for a class of SIR epidemic models, in scenarios in which the infected population is constrained to be lower than a critical threshold imposed by the ICU (intensive care unit) capacity. The…

Optimization and Control · Mathematics 2024-12-31 Matteo Della Rossa , Lorenzo Freddi , Dan Goreac

We consider a susceptible, infected, and recovered infectious disease model which incorporates a vaccination rate. In particular, we study the problem of choosing the vaccination rate in order to reduce the number of infected individuals to…

Analysis of PDEs · Mathematics 2021-08-30 Ryan Hynd , Dennis Ikpe , Terrance Pendleton

During the Covid-19 pandemic a key role is played by vaccination to combat the virus. There are many possible policies for prioritizing vaccines, and different criteria for optimization: minimize death, time to herd immunity, functioning of…

Populations and Evolution · Quantitative Biology 2022-03-18 Qi Luo , Ryan Weightman , Sean T. McQuade , Mateo Diaz , Emmanuel Trélat , William Barbour , Dan Work , Samitha Samaranayake , Benedetto Piccoli

We study decentralized protection strategies against Susceptible-Infected-Susceptible (SIS) epidemics on networks. We consider a population game framework where nodes choose whether or not to vaccinate themselves, and the epidemic risk is…

Computer Science and Game Theory · Computer Science 2019-03-05 Ashish R. Hota , Shreyas Sundaram

The paper considers the problems of optimal vaccination control in the classical SIR model under constraints on the resource capabilities of the insurance medical system, in particular under constraints on the possible absolute rate of…

Optimization and Control · Mathematics 2025-11-24 Bogdan Norkin , Vladimir Norkin

There are few adapted SIR models in the literature that combine vaccination and logistic growth. In this article, we study bifurcations of a SIR model where the class of Susceptible individuals grows logistically and has been subject to…

Dynamical Systems · Mathematics 2023-04-26 João P. S. Maurício de Carvalho , Alexandre A. Rodrigues

The Susceptible-Infected-Susceptible (SIS) model is a widely used model for the spread of information and infectious diseases, particularly non-immunizing ones, on a graph. Given a highly contagious disease, a natural question is how to…

Machine Learning · Computer Science 2025-06-19 Sepehr Elahi , Paula Mürmann , Patrick Thiran

One long-standing question in epidemiological research is how best to allocate limited amounts of vaccine or similar preventative measures in order to minimize the severity of an epidemic. Much of the literature on the problem of vaccine…

Social and Information Networks · Computer Science 2014-12-02 Krzysztof Drewniak , Joseph Helsing , Armin R. Mikler

Real-time vaccination following an outbreak can effectively mitigate the damage caused by an infectious disease. However, in many cases, available resources are insufficient to vaccinate the entire at-risk population, logistics result in…

Populations and Evolution · Quantitative Biology 2016-03-29 Chantal Nguyen , Jean M. Carlson

We analyze an optimal control version of a simple SIR epidemiology model that includes a partially specified vaccination policy and takes into account fatigue from protracted application of social distancing measures. The model assumes…

Populations and Evolution · Quantitative Biology 2021-08-17 Evangelos F. Magirou

We analyze an optimal control version of a simple SIRS epidemiology model. The policy maker can adopt policies to diminish the contact rate between infected and susceptible individuals, at a specific economic cost. The arrival of a vaccine…

Populations and Evolution · Quantitative Biology 2020-06-09 Evangelos Magirou

Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered,…

Populations and Evolution · Quantitative Biology 2026-05-12 Mingtao Xia , Lucas Böttcher , Tom Chou

We evaluate the efficiency of various heuristic strategies for allocating vaccines against COVID-19 and compare them to strategies found using optimal control theory. Our approach is based on a mathematical model which tracks the spread of…

Populations and Evolution · Quantitative Biology 2022-05-04 Jeta Molla , Alejandro Ponce de León Chávez , Takayuki Hiraoka , Tapio Ala-Nissila , Mikko Kivelä , Lasse Leskelä

The Covid-19 pandemic revealed the difficulties of vaccinating a population under the circumstances marked by urgency and limited availability of doses while balancing benefits associated with distinct guidelines satisfying specific ethical…

Quantitative Methods · Quantitative Biology 2023-06-08 Pedro Ribeiro de Almeida , Vitor Hirata Sanches , Carla Goldman

We propose a new method to immunize populations or computer networks against epidemics which is more efficient than any method considered before. The novelty of our method resides in the way of determining the immunization targets. First we…

Physics and Society · Physics 2015-06-03 Christian M. Schneider , Tamara Mihaljev , Hans J. Herrmann

The outbreak of COVID-19 led to a record-breaking race to develop a vaccine. However, the limited vaccine capacity creates another massive challenge: how to distribute vaccines to mitigate the near-end impact of the pandemic? In the United…

Populations and Evolution · Quantitative Biology 2021-07-20 Dimitris Bertsimas , Vassilis Digalakis , Alexander Jacquillat , Michael Lingzhi Li , Alessandro Previero