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An essential component in proton radiotherapy is the algorithm to calculate the radiation dose to be delivered to the patient. The most common dose algorithms are fast but they are approximate analytical approaches. However their level of…

Medical Physics · Physics 2015-05-20 Pablo P Yepes , Dragan Mirkovic , Phillip J Taddei

Online adaptive radiation therapy (ART) is an attractive concept that promises the ability to deliver an optimal treatment in response to the inter-fraction variability in patient anatomy. However, it has yet to be realized due to technical…

Medical Physics · Physics 2015-05-14 Xuejun Gu , Dongju Choi , Chunhua Men , Hubert Pan , Amitava Majumdar , Steve B. Jiang

Monte Carlo (MC) simulation is commonly considered to be the most accurate dose calculation method in radiotherapy. However, its efficiency still requires improvement for many routine clinical applications. In this paper, we present our…

Medical Physics · Physics 2015-05-28 Xun Jia , Xuejun Gu , Yan Jiang Graves , Michael Folkerts , Steve B. Jiang

Optimization plays a central role in modern radiation therapy, where it is used to determine optimal treatment machine parameters in order to deliver precise doses adapted to each patient case. In general, solving the optimization problems…

Optimization and Control · Mathematics 2024-05-07 Felix Liu , Albin Fredriksson , Stefano Markidis

The Random Phase Approximation (RPA) for correlation energy in the grid-based projector augmented wave (gpaw) code is accelerated by porting to the Graphics Processing Unit (GPU) architecture. The acceleration is achieved by grouping…

Computational Physics · Physics 2013-07-31 Jun Yan , Lin Li , Christopher O'Grady

Monte Carlo simulation is the most accurate method for absorbed dose calculations in radiotherapy. Its efficiency still requires improvement for routine clinical applications, especially for online adaptive radiotherapy. In this paper, we…

Medical Physics · Physics 2015-05-14 Xun Jia , Xuejun Gu , Josep Sempau , Dongju Choi , Amitava Majumdar , Steve B. Jiang

The widespread adoption of on-board volumetric imaging in cancer radiotherapy has stimulated research efforts to develop online adaptive radiotherapy techniques to handle the inter-fraction variation of the patient's geometry. Such efforts…

Medical Physics · Physics 2015-05-14 Chunhua Men , Xuejun Gu , Dongju Choi , Amitava Majumdar , Ziyi Zheng , Klaus Mueller , Steve B. Jiang

The gamma-index dose comparison tool has been widely used to compare dose distributions in cancer radiotherapy. The accurate calculation of gamma-index requires an exhaustive search of the closest Euclidean distance in the high-resolution…

Medical Physics · Physics 2015-05-20 Xuejun Gu , Xun Jia , Steve B. Jiang

In this paper we describe and demonstrate a C++ code written to determine the trajectory of particles traversing oriented single crystals and a CUDA code written to evaluate the radiation spectra from charged particles with arbitrary…

Computational Physics · Physics 2019-10-24 Christian Flohr Nielsen

Radiation therapy (RT) is a medical treatment to kill cancer cells or shrink tumors. To manually schedule patients for RT is a time-consuming and challenging task. By the use of optimization, patient schedules for RT can be created…

Optimization and Control · Mathematics 2023-05-04 Sara Frimodig , Per Enqvist , Mats Carlsson , Carole Mercier

Purpose: The presence of respiratory motion during radiation treatment leads to degradation of the expected dose distribution, both for target coverage and healthy-tissue sparing, particularly for techniques like pencil-beam scanning proton…

Targeting at the development of an accurate and efficient dose calculation engine for online adaptive radiotherapy, we have implemented a finite size pencil beam (FSPB) algorithm with a 3D-density correction method on GPU. This new…

Medical Physics · Physics 2015-05-27 Xuejun Gu , Urszula Jelen , Jinsheng Li , Xun Jia , Steve B. Jiang

Radiotherapy (RT) planning is complex, subjective, and time-intensive. Advances with artificial intelligence (AI) promise to improve its precision and efficiency, but progress is often limited by the scarcity of large, standardized…

The challenge of removing cancerous cells lies in the limitation of organ at risk, which restricts the ability to increase the radiation dose adequately for enhancing treatment effectiveness. This survey provides a comprehensive overview of…

Medical Physics · Physics 2023-07-27 Amir Moslemi , Navid Khaledi

Artificial intelligence-based radiation therapy (RT) planning has the potential to reduce planning time and inter-planner variability, improving efficiency and consistency in clinical workflows. Most existing automated approaches rely on…

Online adaptive radiation therapy (ART) has great promise to significantly reduce normal tissue toxicity and/or improve tumor control through real-time treatment adaptations based on the current patient anatomy. However, the major technical…

Medical Physics · Physics 2015-05-18 Chunhua Men , Xun Jia , Steve. B. Jiang

We accelerated an ab-initio molecular QMC calculation by using GPGPU. Only the bottle-neck part of the calculation is replaced by CUDA subroutine and performed on GPU. The performance on a (single core CPU + GPU) is compared with that on a…

Computational Physics · Physics 2012-04-06 Yutaka Uejima , Tomoharu Terashima , Ryo Maezono

The modern workflow for radiation therapy treatment planning involves mathematical optimization to determine optimal treatment machine parameters for each patient case. The optimization problems can be computationally expensive, requiring…

Mathematical Software · Computer Science 2023-05-30 Felix Liu , Måns I. Andersson , Albin Fredriksson , Stefano Markidis

Monte Carlo (MC) simulation is considered the gold standard method for radiotherapy dose calculation. However, achieving high precision requires a large number of simulation histories, which is time consuming. The use of computer graphics…

Computer Vision and Pattern Recognition · Computer Science 2020-12-24 Ti Bai , Biling Wang , Dan Nguyen , Steve Jiang

Background: Radiotherapy treatment planning involves solving large-scale optimization problems that are often approximated and solved sub-optimally due to time constraints. Central to these problems is the dose influence matrix which…

Medical Physics · Physics 2024-10-02 Mojtaba Tefagh , Gourav Jhanwar , Masoud Zarepisheh
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