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This paper describes some applications of GPU acceleration in ab initio nuclear structure calculations. Specifically, we discuss GPU acceleration of the software package MFDn, a parallel nuclear structure eigensolver. We modify the matrix…

Radiotherapy treatment planning currently requires many trail-and-error iterations between the planner and treatment planning system, as well as between the planner and physician for discussion/consultation. The physician's preferences for…

Medical Physics · Physics 2019-08-01 Dan Nguyen , Azar Sadeghnejad Barkousaraie , Chenyang Shen , Xun Jia , Steve Jiang

Objective: Radiation therapy treatment planning is a time-consuming process involving iterative adjustments of hyperparameters. To automate the treatment planning process, we propose a meta-optimization framework, called MetaPlanner (MP).…

Medical Physics · Physics 2022-02-22 Charles Huang , Yusuke Nomura , Yong Yang , Lei Xing

Recently, X-ray imaging dose from computed tomography (CT) or cone beam CT (CBCT) scans has become a serious concern. Patient-specific imaging dose calculation has been proposed for the purpose of dose management. While Monte Carlo (MC)…

Medical Physics · Physics 2015-05-30 Xun Jia , Hao Yan , Xuejun Gu , Steve B. Jiang

In radiation therapy, mathematical methods have been used for optimizing treatment planning for delivery of sufficient dose to the cancerous cells while keeping the dose to critical surrounding structures minimal. This optimization problem…

Medical Physics · Physics 2015-06-16 Hamed Yarmand , David Craft

We consider differential Lyapunov and Riccati equations, and generalized versions thereof. Such equations arise in many different areas and are especially important within the field of optimal control. In order to approximate their…

Numerical Analysis · Mathematics 2018-10-23 Hermann Mena , Lena-Maria Pfurtscheller , Tony Stillfjord

In this paper, we present a computationally efficient trajectory optimizer that can exploit GPUs to jointly compute trajectories of tens of agents in under a second. At the heart of our optimizer is a novel reformulation of the non-convex…

Robotics · Computer Science 2020-11-10 Fatemeh Rastgar , Houman Masnavi , Jatan Shrestha , Karl Kruusamae , Alvo Aabloo , Arun Kumar Singh

Intensity-modulated radiation therapy (IMRT) allows for the design of customized, highly-conformal treatments for cancer patients. Creating IMRT treatment plans, however, is a mathematically complex process, which is often tackled in…

Optimization and Control · Mathematics 2022-03-18 Danielle A. Ripsman , Thomas G. Purdie , Timothy C. Y. Chan , Houra Mahmoudzadeh

Gravitational lensing calculation using a direct inverse ray-shooting approach is a computationally expensive way to determine magnification maps, caustic patterns, and light-curves (e.g. as a function of source profile and size). However,…

Instrumentation and Methods for Astrophysics · Physics 2009-09-28 Alexander C. Thompson , Christopher J. Fluke , David G. Barnes , Benjamin R. Barsdell

This study presents FREDopt, a newly developed GPU-accelerated open-source optimization software for simultaneous proton dose and dose-averaged LET (LETd) optimization in IMPT treatment planning. FREDopt was implemented entirely in Python,…

Penetration depth calculation quantifies the extent of overlap between two objects and is crucial in fields like simulations, the metaverse, and robotics. Recognizing its significance, efforts have been made to accelerate this computation…

Graphics · Computer Science 2025-09-17 YoungWoo Kim , Sungmin Kwon , Duksu Kim

Non-coplanar Intensity-Modulated Radiation Therapy (IMRT) goes a step further by orienting the gantry carrying the radiation beam and the patient couch in a non-coplanar manner to accurately target the cancer region and better avoid…

Medical Physics · Physics 2023-05-16 Fang Guo , Franklin Okoli , Ulrike Schick , Dimitris Visvikis , Antoine Valeri , Julien Bert

Many emerging cyber-physical systems, such as autonomous vehicles and robots, rely heavily on artificial intelligence and machine learning algorithms to perform important system operations. Since these highly parallel applications are…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-02-07 An Zou , Jing Li , Christopher D. Gill , Xuan Zhang

This article examines the critical role of fast Monte Carlo dose calculations in advancing proton therapy techniques, particularly in the context of increasing treatment customization and precision. As adaptive radiotherapy and other…

Medical Physics · Physics 2024-04-24 Jason Holmes , Hongying Feng , Lian Zhang , Michael Fix , Steve B. Jiang , Wei Liu

Conventional cancer therapies include surgery, radiation therapy, chemotherapy, and, more recently, immunotherapy. These modalities are often combined to improve the therapeutic index. The general concept of radiation therapy is to increase…

We introduce an approach for the real-time (2Hz) creation of a dense map and alignment of a moving robotic agent within that map by rendering using a Graphics Processing Unit (GPU). This is done by recasting the scan alignment part of the…

Computer Vision and Pattern Recognition · Computer Science 2017-02-23 Julian Ryde , Xuchu , Ding

Purpose: Cone-beam CT (CBCT) plays an important role in image guided radiation therapy (IGRT). However, the large radiation dose from serial CBCT scans in most IGRT procedures raises a clinical concern, especially for pediatric patients who…

Medical Physics · Physics 2015-05-18 Xun Jia , Yifei Lou , Ruijiang Li , William Y. Song , Steve B. Jiang

Purpose: Many planning methods for high dose rate (HDR) brachytherapy treatment planning require an iterative approach. A set of computational parameters are hypothesized that will give a dose plan that meets dosimetric criteria. A dose…

Medical Physics · Physics 2016-11-25 Timmy Siauw , Adam Cunha , Alper Atamturk , I-Chow Hsu , Jean Pouliot , Ken Goldberg

Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors…

Cancer is a primary cause of morbidity and mortality worldwide. The radiotherapy plays a more and more important role in cancer treatment. In the radiotherapy, the dose distribution maps in patient need to be calculated and evaluated for…

Medical Physics · Physics 2019-10-18 Zhao Peng , Hongming Shan , Tianyu Liu , Xi Pei , Jieping Zhou , Ge Wang , X. George Xu