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Objective digital data is scarce yet needed in many domains to enable research that can transform the standard of healthcare. While data from consumer-grade wearables and smartphones is more accessible, there is critical need for similar…

Computers and Society · Computer Science 2023-09-20 Temiloluwa Prioleau , Abigail Bartolome , Richard Comi , Catherine Stanger

Automatic diagnosis (AD), a critical application of AI in healthcare, employs machine learning techniques to assist doctors in gathering patient symptom information for precise disease diagnosis. The Transformer-based method utilizes an…

Computation and Language · Computer Science 2023-07-18 Huimin Wang , Wai-Chung Kwan , Kam-Fai Wong , Yefeng Zheng

Chronic Obstructive Pulmonary Disorder (COPD) is an irreversible and progressive disease which is highly heritable. Clinically, COPD is defined using the summary measures derived from a spirometry test but these are not always adequate.…

Machine Learning · Computer Science 2024-11-15 Soham Gadgil , Joshua Galanter , Mohammadreza Negahdar

Drug-side effect research is vital for understanding adverse reactions arising in complex multi-drug therapies. However, the scarcity of higher-order datasets that capture the combinatorial effects of multiple drugs severely limits progress…

Machine Learning · Computer Science 2025-02-11 Zhaoying Wang , Yingdan Shi , Xiang Liu , Can Chen , Jun Wen , Ren Wang

The opioid epidemic remains a major public health challenge in the United States, requiring a multi-pronged intervention approach to mitigate harms to communities. Given the heterogeneity of the epidemic across the country, it is crucial…

Applications · Statistics 2026-04-13 Abdulrahman A. Ahmed , M. Amin Rahimian , Qiushi Chen , Praveen Kumar

Recent remarkable success in the deep-learning industries has unprecedentedly increased the need for reliable model deployment. For example, the model should alert the user if the produced model outputs might not be reliable. Previous…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Dasol Choi , Dongbin Na

Endometriosis is a non-malignant disorder that affects 176 million women globally. Diagnostic delays result in severe dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility. Therefore, there is a significant need to diagnose…

Image and Video Processing · Electrical Eng. & Systems 2023-02-21 Adrian Balica , Jennifer Dai , Kayla Piiwaa , Xiao Qi , Ashlee N. Green , Nancy Phillips , Susan Egan , Ilker Hacihaliloglu

To curate a high-quality dataset, identifying data variance between the internal and external sources is a fundamental and crucial step. However, methods to detect shift or variance in data have not been significantly researched. Challenges…

Image and Video Processing · Electrical Eng. & Systems 2021-12-30 Xiaoyuan Guo , Judy Wawira Gichoya , Hari Trivedi , Saptarshi Purkayastha , Imon Banerjee

We studied a generalized question: chronic diseases like ME/CFS and long COVID exhibit high heterogeneity with multifactorial etiology and progression, complicating diagnosis and treatment. To address this, we developed BioMapAI, an…

Genomics · Quantitative Biology 2025-06-23 Ruoyun Xiong

Oral epithelial dysplasia (OED) is a premalignant histopathological diagnosis given to lesions of the oral cavity. OED grading is subject to large inter/intra-rater variability, resulting in the under/over-treatment of patients. We…

With advanced imaging, sequencing, and profiling technologies, multiple omics data become increasingly available and hold promises for many healthcare applications such as cancer diagnosis and treatment. Multimodal learning for integrative…

Genomics · Quantitative Biology 2022-12-20 Sina Tabakhi , Mohammod Naimul Islam Suvon , Pegah Ahadian , Haiping Lu

Urinalysis is a standard diagnostic test to detect urinary system related problems. The automation of urinalysis will reduce the overall diagnostic time. Recent studies used urine microscopic datasets for designing deep learning based…

Quantitative Methods · Quantitative Biology 2021-11-23 Dipam Goswami , Hari Om Aggrawal , Rajiv Gupta , Vinti Agarwal

Inferring causality using longitudinal observational databases is challenging due to the passive way the data are collected. The majority of associations found within longitudinal observational data are often non-causal and occur due to…

Computational Engineering, Finance, and Science · Computer Science 2016-11-17 Jenna Reps , Uwe Aickelin

Major depressive disorder (MDD) impacts more than 300 million people worldwide, highlighting a significant public health issue. However, the uneven distribution of medical resources and the complexity of diagnostic methods have resulted in…

Computation and Language · Computer Science 2025-05-02 Yuyang Sha , Hongxin Pan , Wei Xu , Weiyu Meng , Gang Luo , Xinyu Du , Xiaobing Zhai , Henry H. Y. Tong , Caijuan Shi , Kefeng Li

Advances in medical imaging technologies have enabled the collection of longitudinal images, which involve repeated scanning of the same patients over time, to monitor disease progression. However, predictive modeling of such data remains…

Image and Video Processing · Electrical Eng. & Systems 2025-04-25 Chen Liu , Ke Xu , Liangbo L. Shen , Guillaume Huguet , Zilong Wang , Alexander Tong , Danilo Bzdok , Jay Stewart , Jay C. Wang , Lucian V. Del Priore , Smita Krishnaswamy

Datasets often exhibit violations of expected monotonic trends - for example, higher education level correlating with higher average salary, newer homes being more expensive, or diabetes prevalence increasing with age. We address the…

Databases · Computer Science 2025-12-10 Shunit Agmon , Jonathan Gal , Amir Gilad , Ester Livshits , Or Mutay , Brit Youngmann , Benny Kimelfeld

As machine learning and artificial intelligence are more frequently being leveraged to tackle problems in the health sector, there has been increased interest in utilizing them in clinical decision-support. This has historically been the…

Machine Learning · Computer Science 2022-04-12 Adrienne Kline , Hanyin Wang , Yikuan Li , Saya Dennis , Meghan Hutch , Zhenxing Xu , Fei Wang , Feixiong Cheng , Yuan Luo

Chronic wounds affect 8.5 million Americans, particularly the elderly and patients with diabetes. These wounds can take up to nine months to heal, making regular care essential to ensure healing and prevent severe outcomes like limb…

Machine Learning · Computer Science 2025-01-24 Reza Saadati Fard , Emmanuel Agu , Palawat Busaranuvong , Deepak Kumar , Shefalika Gautam , Bengisu Tulu , Diane Strong

Acute ischaemic stroke, caused by an interruption in blood flow to brain tissue, is a leading cause of disability and mortality worldwide. The selection of patients for the most optimal ischaemic stroke treatment is a crucial step for a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Zeynel A. Samak , Philip Clatworthy , Majid Mirmehdi

Deep neural networks are often applied to medical images to automate the problem of medical diagnosis. However, a more clinically relevant question that practitioners usually face is how to predict the future trajectory of a disease.…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Huy Hoang Nguyen , Matthew B. Blaschko , Simo Saarakkala , Aleksei Tiulpin