Related papers: Propagation fronts in a simplified model of tumor …
We consider a Gatenby--Gawlinski-type model of invasive tumors in the presence of an Allee effect. We describe the construction of bistable one-dimensional traveling fronts using singular perturbation techniques in different parameter…
The Gatenby-Gawlinski model for cancer invasion is object of analysis in order to investigate the mathematical framework behind the model working by means of suitable reductions. We perform numerical simulations to study the…
We analyse a novel mathematical model of malignant invasion which takes the form of a two-phase moving boundary problem describing the invasion of a population of malignant cells into a population of background tissue, such as skin. Cells…
In this paper, we carry out a travelling-wave analysis of a model of tumour invasion with degenerate, cross-dependent diffusion. We consider two types of invasive fronts of tumour tissue into extracellular matrix (ECM), which represents…
In this work, we introduce a variant of the Gatenby-Gawlinski model for acid-mediated tumor invasion in the one-dimensional experimental setting, accounting for heterogeneous diffusion of the lactic acid across the surrounding healthy…
In this manuscript, we prove the existence of slow and fast traveling wave solutions in the original Gatenby--Gawlinski model. We prove the existence of a slow traveling wave solution with an interstitial gap. This interstitial gap has…
We study the existence and uniqueness of wavefronts to the scalar reaction-diffusion equations $u_{t}(t,x) = \Delta u(t,x) - u(t,x) + g(u(t-h,x)),$ with monotone delayed reaction term $g: \R_+ \to \R_+$ and $h >0$. We are mostly interested…
We show that propagation speeds in invasion processes modeled by reaction-diffusion systems are determined by marginal spectral stability conditions, as predicted by the marginal stability conjecture. This conjecture was recently settled in…
In this paper we analyse a previously proposed cell-based model of glioblastoma (brain tumour) growth, which is based on the assumption that the cancer cells switch phenotypes between a proliferative and motile state (Gerlee and Nelander,…
In this paper we study the invasion fronts of spatially periodic monotone reaction-diffusion systems in a multi-dimensional setting. We study the pulsating traveling waves that connect the trivial equilibrium, for which all components of…
This article addresses the issue of global convergence towards pushed travelling fronts for solutions of parabolic systems of the form \[ u_t = - \nabla V(u) + u_{xx} \,, \] where the potential $V$ is coercive at infinity. It is proved…
We consider a diffuse interface model for tumor growth recently proposed in [Y. Chen, S.M. Wise, V.B. Shenoy, J.S. Lowengrub, A stable scheme for a nonlinear, multiphase tumor growth model with an elastic membrane, Int. J. Numer. Methods…
Analysis of invasion front has been widely used to decipher biological properties, as well as the growth dynamics of the corresponding populations. Likewise, the invasion front of tumors has been investigated, from which insights into the…
This article investigates a mathematical model for bushfire propagation, focusing on the existence and properties of translating solutions. We obtain quantitative bounds on the environmental diffusion coefficient and ignition kernels,…
For nonlinear parabolic gradient systems of the form \[ u_t = -\nabla V(u) + u_{xx} \,, \] where the spatial domain is the whole real line, the state variable $u$ is multidimensional, and the potential function $V$ is coercive at infinity,…
In this work, we study the propagation of wildfires using an advection--diffusion--reaction model which also includes convective and radiative heat loss. An existing model is discussed \cite{asensio_2002} and a physically consistent…
At the continuous level, we consider two types of tumor growth models: the cell density model, which is based on the fluid mechanical construction, is more favorable for scientific interpretation and numerical simulations; and the free…
Objective: The overarching objective is to make the definition of the clinical target volume (CTV) in radiation oncology less subjective and more scientifically based. The specific objective of this study is to investigate similarities and…
We study front propagation problems for forced mean curvature flows and their phase field variants that take place in stratified media, i.e., heterogeneous media whose characteristics do not vary in one direction. We consider phase change…
This paper studies the phenomenon of invasion for heterogeneous reaction-diffusion equations in periodic domains with monostable and combustion reaction terms. We give an answer to a question rised by Berestycki, Hamel and Nadirashvili in…