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Systemic amyloidosis is a group of diseases characterized by the deposition of misfolded proteins in various organs and tissues, leading to progressive organ dysfunction and failure. Congo red stain is the gold standard chemical stain for…

Amyloidosis is a protein misfolding disease caused by the deposition of large, insoluble aggregates (amyloid fibrils) of protein in a tissue, which has been associated with various conditions, such as lymphoid disorders, Alzheimer's…

In chronic liver disease, liver fibrosis develops as excessive deposition of extracellular matrix macromolecules, predominantly collagens, progressively form fibrous scars that disrupt the hepatic architecture, and fibrosis, iron, and fat…

Objectives: The role of advanced diffusion-weighted imaging (DWI) in chronic liver disease (CLD) has not been fully studied. Chronic liver disease (CLD) is a progressive deterioration of liver functions, caused by one or more etiology. This…

Tissues and Organs · Quantitative Biology 2025-09-10 Jiqing Huang , Benjamin Leporq , Valérie Hervieu , Sophie Gaillard , Jerome Dumortier , Olivier Beuf , Hélène Ratiney

We present an end-to-end deep learning framework for automated liver cirrhosis stage estimation from multi-sequence MRI. Cirrhosis is the severe scarring (fibrosis) of the liver and a common endpoint of various chronic liver diseases. Early…

The results of modeling the dependence of the red leak of photometric filters on various factors (color index V-R, luminosity class, interstellar reddening, airmass and PWV) during observations of stars are presented. The error arising from…

Instrumentation and Methods for Astrophysics · Physics 2024-01-09 G. E. Nikishev , N. A. Maslennikova , A. M. Tatarnikov , K. Yu. Parusov , A. A. Belinski

Liver fibrosis represents the accumulation of excessive extracellular matrix caused by sustained hepatic injury. It disrupts normal lobular architecture and function, increasing the chances of cirrhosis and liver failure. Precise staging of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-01 Yang Zhou , Kunhao Yuan , Ye Wei , Jishizhan Chen

End-Stage Liver Disease (ESLD), a complex condition, has high rates of co-occurring comorbidities affecting multiple organ systems. There is no clear evidence-based practice (EBP) guidelines addressing the progression of comorbidities in…

Quantitative Methods · Quantitative Biology 2024-10-17 Julia Tacherel , Kiruthika Balakrishnan , Gyorgy Simon , Lisiane Pruinelli

Sarcoidosis is a rare inflammatory disease characterized by the formation of granulomas in various organs. The disease presents diagnostic and treatment challenges due to its diverse manifestations and unpredictable nature. In this study,…

Computation and Language · Computer Science 2024-10-29 Nan Miles Xi , Hong-Long Ji , Lin Wang

Non-alcoholic fatty liver disease (NAFLD) is a clinicopathological syndrome characterized by hepatic steatosis resulting from the exclusion of alcohol and other identifiable liver-damaging factors. It has emerged as a leading cause of…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Shan Cao , Qunsheng Ruan , Qingfeng Wu , Weiqiang Lin

Systemic lupus erythematosus (SLE) is an autoimmune disease in which the immune system of the patient starts attacking healthy tissues of the body. Lupus Nephritis (LN) refers to the inflammation of kidney tissues resulting in renal failure…

Image and Video Processing · Electrical Eng. & Systems 2021-12-15 Akash Gupta , Anirudh Reddy , CV Jawahar , PK Vinod

Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver diseases (CLD) which can progress to liver cancer. The severity and treatment of NAFLD is determined by NAFLD Activity Scores (NAS)and liver…

Image and Video Processing · Electrical Eng. & Systems 2021-03-16 Ananya Jana , Hui Qu , Carlos D. Minacapelli , Carolyn Catalano , Vinod Rustgi , Dimitris Metaxas

We propose a fully-automated method for accurate and robust detection and segmentation of potentially cancerous lesions found in the liver and in lymph nodes. The process is performed in three steps, including organ detection, lesion…

Computer Vision and Pattern Recognition · Computer Science 2017-03-21 Assaf Hoogi , John W. Lambert , Yefeng Zheng , Dorin Comaniciu , Daniel L. Rubin

Protein amyloidosis is a cytopathological process characterized by the formation of highly beta-sheet-rich fibrils. How this process occurs and how to prevent/treat the associated diseases are not completely understood. Here, we carry out a…

Soft Condensed Matter · Physics 2007-05-23 Chinlin Guo , Herbert Levine , David A. Kessler

Background: Cirrhosis is a progressive liver disease with high mortality and frequent complications, notably acute kidney injury (AKI), which occurs in up to 50% of hospitalized patients and worsens outcomes. AKI stems from complex…

Machine Learning · Computer Science 2025-08-15 Li Sun , Shuheng Chen , Junyi Fan , Yong Si , Minoo Ahmadi , Elham Pishgar , Kamiar Alaei , Maryam Pishgar

Hepatocellular carcinoma (HCC) is the second most frequent cause of malignancy-related death and is one of the diseases with the highest incidence in the world. Because the liver is the only organ in the human body that is supplied by two…

Computer Vision and Pattern Recognition · Computer Science 2019-07-25 Jiechao Ma , Yingqian Chen , Yu Chen , Fengkai Wan , Sumin Xue , Ziping Li , Shiting Feng

Liver diseases are a serious health concern in the world, which requires precise and timely diagnosis to enhance the survival chances of patients. The current literature implemented numerous machine learning and deep learning models to…

Liver diseases pose a significant global health burden, impacting many individuals and having substantial economic and social consequences. Rising liver problems are considered a fatal disease in many countries, such as Egypt and Moldova.…

Artificial Intelligence · Computer Science 2025-03-21 Ritesh Chandra , Sadhana Tiwari , Satyam Rastogi , Sonali Agarwal

The shortage of nephrologists and the growing public health concern over renal failure have spurred the demand for AI systems capable of autonomously detecting kidney abnormalities. Renal failure, marked by a gradual decline in kidney…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Tahmim Hossain , Faisal Sayed , Solehin Islam

Systemic lupus erythematosus (SLE) is the tenth leading cause of death in females 15-24 years old in the US. The diversity of symptoms and immune pathways expressed in SLE patients causes difficulties in treating SLE as well as in new…

Genomics · Quantitative Biology 2020-11-11 Aditi Deokar
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