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World Health Organization reports that African Trypanosomiasis affects mostly poor populations living in remote rural areas of Africa that can be fatal if properly not treated. This paper presents Dempster-Shafer Theory for the detection of…
Liquid-liquid phase separation (LLPS) is currently of great interest in cell biology. LLPS is an example of what is called an emergent phenomenon -- an idea that comes from condensed-matter physics. Emergent phenomena have the…
Tuberculosis relapse is a barrier to shorter treatment. It is thought that lipid rich cells, phenotypically resistant to antibiotics, may play a major role. Most studies investigating relapse use sputum samples although tissue bacteria may…
Non-alcoholic fatty liver disease (NAFLD) is a prevalent chronic liver disorder characterized by the excessive accumulation of fat in the liver in individuals who do not consume significant amounts of alcohol, including risk factors like…
Diabetic Retinopathy is one of the most familiar diseases and is a diabetes complication that affects eyes. Initially, diabetic retinopathy may cause no symptoms or only mild vision problems. Eventually, it can cause blindness. So early…
Liver cirrhosis represents the end stage of chronic liver disease, characterized by extensive fibrosis and nodular regeneration that significantly increases mortality risk. While magnetic resonance imaging (MRI) offers a non-invasive…
Diabetic retinopathy is an ocular condition that affects individuals with diabetes mellitus. It is a common complication of diabetes that can impact the eyes and lead to vision loss. One method for diagnosing diabetic retinopathy is the…
Liver cirrhosis is an insidious condition involving the substitution of normal liver tissue with fibrous scar tissue and causing major health complications. The conventional method of diagnosis using liver biopsy is invasive and, therefore,…
Intraperitoneal and catheter exit site infections are the most common complications associated with prolonged peritoneal dialysis (PD) therapy used for treating the patients with end stage renal failure (ESRF). Recurrent and persistent…
Kidney stone disease poses a major burden to patients and healthcare systems around the world. The formation of kidney stones may occur over months or years, but many patients are diagnosed at a late stage, suffer excruciating pain, and…
Rare diseases are very difficult to identify among large number of other possible diagnoses. Better availability of patient data and improvement in machine learning algorithms empower us to tackle this problem computationally. In this…
In patients with primary biliary cholangitis (PBC), the serum liver biochemistry measured during treatment with ursodeoxycholic acid (the UDCA response) accurately predicts long-term outcome. In this study we sought to use liver…
Globally, chronic liver disease continues to be a major health concern that requires precise predictive models for prompt detection and treatment. Using the Indian Liver Patient Dataset (ILPD) from the University of California at Irvine's…
Vlahos et al., Ref. 1, NPJ Clean water. 4, 50 (2021) have reported the presence of pesticide contamination above safe levels in a "single time-point analysis" of well water in a region in Sri Lanka where chronic kidney disease of unknown…
Liver allograft failure occurs in approximately 20% of liver transplant recipients within five years post-transplant, leading to mortality or the need for retransplantation. Providing an accurate and interpretable model for individualized…
Colorectal liver metastasis is one of most aggressive liver malignancies. While the definition of lesion type based on CT images determines the diagnosis and therapeutic strategy, the discrimination between cancerous and non-cancerous…
Based on three years of Fermi Large Area Telescope (LAT) gamma-ray data of the Virgo cluster, evidence for an extended emission associated with dark matter pair annihilation in the b b-bar channel has been reported by Han et al. [1]. After…
An accurate steatosis quantification with pathology tissue samples is of high clinical importance. However, such pathology measurement is manually made in most clinical practices, subject to severe reader variability due to large sampling…
Introduction: Automated Lung X-Ray Abnormality Detection System is the application which distinguish the normal x-ray images from infected x-ray images and highlight area considered for prediction, with the recent pandemic a need to have a…
Drug-induced liver injury (DILI) is the most common cause of acute liver failure and a frequent reason for withdrawal of candidate drugs during preclinical and clinical testing. An important type of DILI is cholestatic liver injury, caused…