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We propose a three dimensional mechanical model of embryonic tissue dynamics. Mechanically coupled adherent cells are represented as particles interconnected with elastic beams which can exert non-central forces and torques. Tissue…

Biological Physics · Physics 2015-06-22 Andras Czirok , Dona Greta Isai

Background and Aim: Decellularized uterine extracellular matrix (dUECM) offers a promising bioactive scaffold for uterine tissue engineering, but its application in 3D constructs has been limited by fabrication challenges. This study aimed…

Finite element simulations are essential in biomechanics, enabling detailed modeling of tissues and organs. However, architectural inefficiencies in current hardware and software stacks limit performance and scalability, especially for…

Hardware Architecture · Computer Science 2025-10-21 Hana Chitsaz , Johnson Umeike , Amirmahdi Namjoo , Babak N. Safa , Bahar Asgari

The combination of Finite Element Method (FEM) simulation and experimental photo-elasticity provides both qualitative and quantitative information about the stress field in a polymer composite and particularly along the fibre-matrix…

Materials Science · Physics 2007-05-23 H. Matthias Deuschle , Falk K. Wittel , Henry Gerhard , Gerhard Busse , Bernd-H. Kroeplin

Characterizing the softness of deformable materials having partial elastic and partial viscous behaviour via soft lubrication experiments has emerged as a versatile and robust methodology in recent times. However, a straightforward…

Soft Condensed Matter · Physics 2021-07-22 Pratyaksh Karan , Jeevanjyoti Chakraborty , Suman Chakraborty

Modeling biological soft tissue is complex in part due to material heterogeneity. Microstructural patterns, which play a major role in defining the mechanical behavior of these tissues, are both challenging to characterize, and difficult to…

Machine Learning · Computer Science 2022-07-19 Hiba Kobeissi , Saeed Mohammadzadeh , Emma Lejeune

In recent years, a number of experimental studies have been conducted to investigate the mechanical behavior of water-saturated biological tissues like articular cartilage under dynamic loading. For in vivo measurements of tissue viability,…

Analysis of PDEs · Mathematics 2012-07-20 Ivan Argatov

In this paper, we present a unit cell showing a band-gap in the lower acoustic domain. The corresponding metamaterial is made up of a periodic arrangement of this unit cell. We rigorously show that the relaxed micromorphic model can be used…

Applied Physics · Physics 2022-09-07 F. Demore , G. Rizzi , M. Collet , P. Neff , A. Madeo

Mammography is a specific type of breast imaging that uses low-dose X-rays to detect cancer in early stage. During the exam, the women breast is compressed between two plates until a nearly uniform breast thickness is obtained. This…

Medical Physics · Physics 2018-11-26 Mîra Anna , Ann-Katherine Carton , Serge Muller , Yohan Payan

Accurate and efficient prediction of soft tissue temperatures is essential to computer-assisted treatment systems for thermal ablation. It can be used to predict tissue temperatures and ablation volumes for personalised treatment planning…

Computational Engineering, Finance, and Science · Computer Science 2022-01-03 Jinao Zhang , Remi Jacob Lay , Stuart K. Roberts , Sunita Chauhan

The study of cells' dynamical properties is essential to a better understanding of several physiological processes. These properties are directly associated with cells' mechanical parameters experimentally achieved through physical stress.…

Soft Condensed Matter · Physics 2022-01-26 G. Ourique , E. F. Teixeira , L. G. Brunnet

Mechanical properties of the tissue engineering scaffolds are known to play a crucial role in tissue regeneration. Here, we have utilized discrete network and finite element models to study fibrous scaffold mechanics and its dependence on…

Soft Condensed Matter · Physics 2025-01-15 Dhruba Jyoti Mech , Mohd Suhail Rizvi

When modelling discontinuities (interfaces) using the finite element method, the standard approach is to use a conforming finite-element mesh in which the mesh matches the interfaces. However, this approach can prove cumbersome if the…

Computational Engineering, Finance, and Science · Computer Science 2024-06-06 Jedrzej Dobrzanski , Kajetan Wojtacki , Stanislaw Stupkiewicz

The heterogeneous micromechanical properties of biological tissues have profound implications across diverse medical and engineering domains. However, identifying full-field heterogeneous elastic properties of soft materials using…

Numerical Analysis · Mathematics 2025-07-09 Wensi Wu , Mitchell Daneker , Kevin T. Turner , Matthew A. Jolley , Lu Lu

This article addresses the research question if and how the finite cell method, an embedded domain finite element method of high order, may be used in the simulation of metal deposition to harvest its computational efficiency. This…

Numerical Analysis · Mathematics 2018-09-26 Ali Özcan , Stefan Kollmannsberger , John N. Jomo , Ernst Rank

Biomembranes and vesicles consisting of multiple phases can attain a multitude of shapes, undergoing complex shape transitions. We study a Cahn--Hilliard model on an evolving hypersurface coupled to Navier--Stokes equations on the surface…

Numerical Analysis · Mathematics 2019-11-01 John W. Barrett , Harald Garcke , Robert Nürnberg

A simulation strategy based in the finite element model was developed to model the corrosion and mechanical properties of biodegradable Mg scaffolds manufactured by laser power bed fusion after immersion in simulated body fluid. Corrosion…

Applied Physics · Physics 2022-01-19 Mohammad Marvi-Mashhadi , Wahaaj Ali , Muzi Li , Carlos González , Javier LLorca

Shape adaptive shape memory alloy hybrid composites (SMAHCs) are composites that incorporate shape memory alloys (SMAs) to realize shape transformation. Despite the availability of numerous analytical and finite element models for…

Applied Physics · Physics 2026-04-17 Lukas Handl , Max Kaiser , Miro Duhovic , Martin Gurka

A novel 3D micromechanical Finite Element Model (FEM) has been developed to depict the Poynting effect in bi-phasic Representative volume element (RVE) with axons embedded in surrounding extra-cellular matrix (ECM) for simulating the brain…

Medical Physics · Physics 2023-05-03 Mohit Agarwal , Assimina A. Pelegri

Tissue Engineering concerns the three-dimensional cell growth so that bio-artificial tissues could be created and used for transplantation. The recently expressed concerns from the Tissue Engineering research community for a re-direction of…

Tissues and Organs · Quantitative Biology 2008-01-23 Veronica Saravia