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Organ morphology is a key indicator for prostate disease diagnosis and prognosis. For instance, In longitudinal study of prostate cancer patients under active surveillance, the volume, boundary smoothness and their changes are closely…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Qianye Yang , Tom Vercauteren , Yunguan Fu , Francesco Giganti , Nooshin Ghavami , Vasilis Stavrinides , Caroline Moore , Matt Clarkson , Dean Barratt , Yipeng Hu

Quantification of local metabolic tumor volume (MTV) chan-ges after Chemo-radiotherapy would allow accurate tumor response evaluation. Currently, local MTV changes in esophageal (soft-tissue) cancer are measured by registering follow-up PET…

Computer Vision and Pattern Recognition · Computer Science 2018-08-28 Sadegh Riyahi , Wookjin Choi , Chia-Ju Liu , Saad Nadeem , Shan Tan , Hualiang Zhong , Wengen Chen , Abraham J. Wu , James G. Mechalakos , Joseph O. Deasy , Wei Lu

Multimodal image registration (MIR) is a fundamental procedure in many image-guided therapies. Recently, unsupervised learning-based methods have demonstrated promising performance over accuracy and efficiency in deformable image…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Zhe Xu , Jiangpeng Yan , Jie Luo , Xiu Li , Jayender Jagadeesan

In this study, we introduce statistical modeling methods for pneumothorax deformation using paired cone-beam computed tomography (CT) images. We designed a deformable mesh registration framework for shape changes involving non-linear…

Computational Geometry · Computer Science 2020-12-25 Megumi Nakao , Hinako Maekawa , Katsutaka Mineura , Toyofumi F. Chen-Yoshikawa , Hiroshi Date , Tetsuya Matsuda

Segmentation of multiple organs-at-risk (OARs) is essential for radiation therapy treatment planning and other clinical applications. We developed an Automated deep Learning-based Abdominal Multi-Organ segmentation (ALAMO) framework based…

Image and Video Processing · Electrical Eng. & Systems 2020-08-25 Yuhua Chen , Dan Ruan , Jiayu Xiao , Lixia Wang , Bin Sun , Rola Saouaf , Wensha Yang , Debiao Li , Zhaoyang Fan

Due to the fact that pancreas is an abdominal organ with very large variations in shape and size, automatic and accurate pancreas segmentation can be challenging for medical image analysis. In this work, we proposed a fully automated two…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Ningning Zhao , Nuo Tong , Dan Ruan , Ke Sheng

Background and Purpose: Voxel-based analysis (VBA) helps to identify dose-sensitive regions by aligning individual dose distributions within a common coordinate system (CCS). Accurate deformable image registration (DIR) is essential for…

Medical Physics · Physics 2025-09-26 Xingyue Ruan , Xia Li , Muheng Li , Barbara Bachtiary , Antony Lomax , Zhiling Chen , Ye Zhang

We aim to detect pancreatic ductal adenocarcinoma (PDAC) in abdominal CT scans, which sheds light on early diagnosis of pancreatic cancer. This is a 3D volume classification task with little training data. We propose a two-stage framework,…

Computer Vision and Pattern Recognition · Computer Science 2019-08-22 Fengze Liu , Lingxi Xie , Yingda Xia , Elliot K. Fishman , Alan L. Yuille

Accurate patient positioning is critical for precise radiotherapy dose delivery, as positioning errors can significantly affect treatment outcomes. This study introduces a novel method for tracking loco-regional tissue deformation through…

We propose a PDE-constrained shape registration algorithm that captures the deformation and growth of biological tissue from imaging data. Shape registration is the process of evaluating optimum alignment between pairs of geometries through…

Biological Physics · Physics 2022-04-07 Aishwarya Pawar , Linlin Li , Arun K Gosain , David M Umulis , Adrian B Tepole

Increased organ at risk segmentation accuracy is required to reduce cost and complications for patients receiving radiotherapy treatment. Some deep learning methods for the segmentation of organs at risk use a two stage process where a…

Image and Video Processing · Electrical Eng. & Systems 2023-04-11 Abraham George Smith , Denis Kutnár , Ivan Richter Vogelius , Sune Darkner , Jens Petersen

Non-invasive detection of cardiovascular disorders from radiology scans requires quantitative image analysis of the heart and its substructures. There are well-established measurements that radiologists use for diseases assessment such as…

Machine Learning · Statistics 2017-08-04 Aliasghar Mortazi , Jeremy Burt , Ulas Bagci

Transarterial chemoembolization (TACE) is a preferred treatment option for hepatocellular carcinoma and other liver malignancies, yet it remains a highly challenging procedure due to complex intra-operative vascular navigation and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Zehua Liu , Shihao Zou , Jincai Huang , Yanfang Zhang , Chao Tong , Weixin Si

Image-guided surgery collocates patient-specific data with the physical environment to facilitate surgical decision making in real-time. Unfortunately, these guidance systems commonly become compromised by intraoperative soft-tissue…

Image and Video Processing · Electrical Eng. & Systems 2023-06-12 Morgan Ringel , Jon Heiselman , Winona Richey , Ingrid Meszoely , William Jarnagin , Michael Miga

Nonlinear image registration continues to be a fundamentally important tool in medical image analysis. Diagnostic tasks, image-guided surgery and radiotherapy as well as motion analysis all rely heavily on accurate intra-patient alignment.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Mattias P. Heinrich

Accurate registration of medical images is vital for doctor's diagnosis and quantitative analysis. In this paper, we propose a new deformable medical image registration method based on average geometric transformations and VoxelMorph CNN…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Yongpei Zhu , Zicong Zhou , Guojun Liao , Kehong Yuan

Deformable registration continues to be one of the key challenges in medical image analysis. While iconic registration methods have started to benefit from the recent advances in medical deep learning, the same does not yet apply for the…

Computer Vision and Pattern Recognition · Computer Science 2019-09-18 Lasse Hansen , Doris Dittmer , Mattias P. Heinrich

Due to complexity and invisibility of human organs, diagnosticians need to analyze medical images to determine where the lesion region is, and which kind of disease is, in order to make precise diagnoses. For satisfying clinical purposes…

Quantitative Methods · Quantitative Biology 2017-05-18 Roberto Cavoretto , Alessandra De Rossi , Roberta Freda , Hanli Qiao , Ezio Venturino

This work proposed a novel deep registration pipeline for 3D CT and 2D U/S kidney scans of free breathing, which consists of a feature network, and a 3D-2D CNN-based registration network. The feature network has handcraft texture feature…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Chi Yanling , Xu Yuyu , Liu Huiying , Wu Xiaoxiang , Liu Zhiqiang , Mao Jiawei , Xu Guibin , Huang Weimin

Reconstructing the 3D shape of a deformable environment from the information captured by a moving depth camera is highly relevant to surgery. The underlying challenge is the fact that simultaneously estimating camera motion and tissue…

Computer Vision and Pattern Recognition · Computer Science 2024-08-09 Guido Caccianiga , Julian Nubert , Cesar Cadena , Marco Hutter , Katherine J. Kuchenbecker