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Objective: Four-dimensional computed tomography (4DCT) imaging consists in reconstructing a CT acquisition into multiple phases to track internal organ and tumor motion. It is commonly used in radiotherapy treatment planning to establish…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Yi-Heng Cao , Vincent Bourbonne , François Lucia , Ulrike Schick , Julien Bert , Vincent Jaouen , Dimitris Visvikis

We introduce an approach for image segmentation based on sparse correspondences between keypoints in testing and training images. Keypoints represent automatically identified distinctive image locations, where each keypoint correspondence…

Computer Vision and Pattern Recognition · Computer Science 2018-06-25 Christian Wachinger , Matthew Toews , Georg Langs , William Wells , Polina Golland

The recent application of deep learning technologies in medical image registration has exponentially decreased the registration time and gradually increased registration accuracy when compared to their traditional counterparts. Most of the…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Abdullah Nazib , Clinton Fookes , Olivier Salvado , Dimitri Perrin

Deformable image registration (DIR) is an enabling technology in many diagnostic and therapeutic tasks. Despite this, DIR algorithms have limited clinical use, largely due to a lack of benchmark datasets for quality assurance during…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Edward R Criscuolo , Yao Hao , Zhendong Zhang , Trevor McKeown , Deshan Yang

Purpose: Echocardiography is commonly used as a non-invasive imaging tool in clinical practice for the assessment of cardiac function. However, delineation of the left ventricle is challenging due to the inherent properties of ultrasound…

Image and Video Processing · Electrical Eng. & Systems 2021-09-07 Deepa Krishnaswamy , Abhilash R. Hareendranathan , Tan Suwatanaviroj , Pierre Boulanger , Harald Becher , Michelle Noga , Kumaradevan Punithakumar

Aortic valve (AV) biomechanics play a critical role in maintaining normal cardiac function. Pathological variations, particularly in bicuspid aortic valves, alter leaflet loading, increase strain, and accelerate disease progression.…

Computed tomography (CT) scans are a major source of medical radiation exposure worldwide. In countries like China, the frequency of CT scans has grown rapidly, particularly in routine physical examinations where chest CT scans are…

Medical Physics · Physics 2025-04-10 Zirui Ye , Bei Yao , Haoran Zheng , Li Tao , Ripeng Wang , Yankui Chang , Zhi Chen , Yingming Zhao , Wei Wei , Xie George Xu

Lung injuries, such as ventilator-induced lung injury and radiation-induced lung injury, can lead to heterogeneous alterations in the biomechanical behavior of the lungs. While imaging methods, e.g., X-ray and static computed tomography…

Medical Physics · Physics 2024-07-08 Sunder Neelakantan , Tanmay Mukherjee , Kyle J. Myers , Rahim Rizi , Reza Avazmohammadi

Image registration of liver dynamic contrast-enhanced computed tomography (DCE-CT) is crucial for diagnosis and image-guided surgical planning of liver cancer. However, intensity variations due to the flow of contrast agents combined with…

Image and Video Processing · Electrical Eng. & Systems 2023-03-09 Peng Xue , Jingyang Zhang , Lei Ma , Mianxin Liu , Yuning Gu , Jiawei Huang , Feihong Liua , Yongsheng Pan , Xiaohuan Cao , Dinggang Shen

The purpose of this study is to develop a deep learning based method that can automatically generate segmentations on cone-beam CT (CBCT) for head and neck online adaptive radiation therapy (ART), where expert-drawn contours in planning CT…

Medical Physics · Physics 2021-02-02 Xiao Liang , Howard Morgan , Dan Nguyen , Steve Jiang

Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART) to account for anatomical changes. Conventional intensity-based DIR methods often fail when image intensities differ. This study evaluates a hybrid…

Medical Physics · Physics 2024-11-27 Keyur D. Shah , James A. Shackleford , Nagarajan Kandasamy , Gregory C. Sharp

In this work we propose a multi-scale recurrent encoder-decoder architecture to predict the breathing induced organ deformation in future frames. The model was trained end-to-end from input images to predict a sequence of motion labels.…

Image and Video Processing · Electrical Eng. & Systems 2020-05-29 Liset Vázquez Romaguera , Rosalie Plantefève , Samuel Kadoury

Image registration is a key technique in medical image analysis to estimate deformations between image pairs. A good deformation model is important for high-quality estimates. However, most existing approaches use ad-hoc deformation models…

Computer Vision and Pattern Recognition · Computer Science 2019-04-23 Marc Niethammer , Roland Kwitt , Francois-Xavier Vialard

Unlike Right Atrium (RA), Left Atrium (LA) presents distinctive challenges, including much thinner myocardial walls, complex and irregular morphology, as well as diversity in individual's structure, making off-the-shelf methods designed for…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Abdul Qayyum , Moona Mazher , Angela Lee , Jose A Solis-Lemus , Imran Razzak , Steven A Niederer

We present an implementation of a new approach to diffeomorphic non-rigid registration of medical images. The method is based on optical flow and warps images via gradient flow with the standard $L^2$ inner product. To compute the…

Computer Vision and Pattern Recognition · Computer Science 2019-04-25 Daniel Grzech , Loïc le Folgoc , Mattias P. Heinrich , Bishesh Khanal , Jakub Moll , Julia A. Schnabel , Ben Glocker , Bernhard Kainz

In multi-view human body capture systems, the recovered 3D geometry or even the acquired imagery data can be heavily corrupted due to occlusions, noise, limited field of- view, etc. Direct estimation of 3D pose, body shape or motion on…

Computer Vision and Pattern Recognition · Computer Science 2018-02-02 Zhong Li , Yu Ji , Wei Yang , Jinwei Ye , Jingyi Yu

Image segmentation plays an essential role in medicine for both diagnostic and interventional tasks. Segmentation approaches are either manual, semi-automated or fully-automated. Manual segmentation offers full control over the quality of…

Computer Vision and Pattern Recognition · Computer Science 2019-03-21 Tomas Sakinis , Fausto Milletari , Holger Roth , Panagiotis Korfiatis , Petro Kostandy , Kenneth Philbrick , Zeynettin Akkus , Ziyue Xu , Daguang Xu , Bradley J. Erickson

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers among the population. Screening for PDACs in dynamic contrast-enhanced CT is beneficial for early diagnosis. In this paper, we investigate the problem of automated…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Yingda Xia , Qihang Yu , Wei Shen , Yuyin Zhou , Elliot K. Fishman , Alan L. Yuille

Organoids are multi-cellular structures which are cultured in vitro from stem cells to resemble specific organs (e.g., brain, liver) in their three-dimensional composition. Dynamic changes in the shape and composition of these model systems…

Quantitative Methods · Quantitative Biology 2022-12-23 Lewis Marsh , Felix Y. Zhou , Xiao Qin , Xin Lu , Helen M. Byrne , Heather A. Harrington

We present a parallel distributed-memory algorithm for large deformation diffeomorphic registration of volumetric images that produces large isochoric deformations (locally volume preserving). Image registration is a key technology in…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-12-25 Andreas Mang , Amir Gholami , George Biros