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The degradation of the acquired signal by Poisson noise is a common problem for various imaging applications, such as medical imaging, night vision and microscopy. Up to now, many state-of-the-art Poisson denoising techniques mainly…

Computer Vision and Pattern Recognition · Computer Science 2015-10-13 Wensen Feng , Yunjin Chen

We demonstrate an electro-optic wide-field method to enable fluorescence lifetime microscopy (FLIM) with high throughput and single-molecule sensitivity. Resonantly driven Pockels cells are used to efficiently gate images at 39 MHz,…

Optics · Physics 2021-09-23 Adam J. Bowman , Mark A. Kasevich

Machine learning (ML) methods are extraordinarily successful at denoising photographic images. The application of such denoising methods to scientific images is, however, often complicated by the difficulty in experimentally obtaining a…

This paper proposes a novel method to filter out the false alarm of LiDAR system by using the temporal correlation of target reflected photons. Because of the inevitable noise, which is due to background light and dark counts of the…

Instrumentation and Detectors · Physics 2017-08-22 Zhenchao Feng , Weiji He , Jian Fang , Guohua Gu , Qian Chen , Ping Zhang , Yuanjin Chen , Beibei Zhou , Minhua Zhou

Mammography is using low-energy X-rays to screen the human breast and is utilized by radiologists to detect breast cancer. Typically radiologists require a mammogram with impeccable image quality for an accurate diagnosis. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2019-12-12 Dominik Eckert , Sulaiman Vesal , Ludwig Ritschl , Steffen Kappler , Andreas Maier

Quantitative phase imaging (QPI) has been widely applied in characterizing cells and tissues. Spatial light interference microscopy (SLIM) is a highly sensitive QPI method, due to its partially coherent illumination and common path…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Yuheng Jiao , Yuchen R. He , Mikhail E. Kandel , Xiaojun Liu , Wenlong Lu , Gabriel Popescu

Recovering a signal from its Fourier intensity underlies many important applications, including lensless imaging and imaging through scattering media. Conventional algorithms for retrieving the phase suffer when noise is present but display…

Image and Video Processing · Electrical Eng. & Systems 2020-03-05 Yaotian Wang , Xiaohang Sun , Jason W. Fleischer

Blind image denoising is an important yet very challenging problem in computer vision due to the complicated acquisition process of real images. In this work we propose a new variational inference method, which integrates both noise…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Zongsheng Yue , Hongwei Yong , Qian Zhao , Lei Zhang , Deyu Meng

In this paper, we introduce a simple, yet powerful pipeline for medical image segmentation that combines Fully Convolutional Networks (FCNs) with Fully Convolutional Residual Networks (FC-ResNets). We propose and examine a design that takes…

Computer Vision and Pattern Recognition · Computer Science 2017-02-20 Michal Drozdzal , Gabriel Chartrand , Eugene Vorontsov , Lisa Di Jorio , An Tang , Adriana Romero , Yoshua Bengio , Chris Pal , Samuel Kadoury

Image denoising is a classical problem in low level computer vision. Model-based optimization methods and deep learning approaches have been the two main strategies for solving the problem. Model-based optimization methods are flexible for…

Computer Vision and Pattern Recognition · Computer Science 2018-12-31 Chang Liu , Zhaowei Shang , Anyong Qin

This study investigates the noise characteristics of intraoperative X-ray fluoroscopic images acquired during real-time image-guided radiotherapy (IGRT), and presents a novel noise image generation method based on the identified noise…

Medical Physics · Physics 2024-11-04 Yongxuan Yan , Fumitake Fujii , Takehiro Shiinoki

Fluorescence guided surgery (FGS) is a promising surgical technique that gives surgeons a unique view of tissue that is used to guide their practice by delineating tissue types and diseased areas. As new fluorescent contrast agents are…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Trevor Seets , Andreas Velten

The restoration of images affected by blur and noise has been widely studied and has broad potential for applications including in medical imaging modalities like computed tomography (CT). Although the blur and noise in CT images can be…

Medical Physics · Physics 2024-07-23 Yijie Yuan , Grace J. Gang , J. Webster Stayman

In this paper, we present an efficient visual SLAM system designed to tackle both short-term and long-term illumination challenges. Our system adopts a hybrid approach that combines deep learning techniques for feature detection and…

Robotics · Computer Science 2025-02-28 Kuan Xu , Yuefan Hao , Shenghai Yuan , Chen Wang , Lihua Xie

Traditional fluid flow predictions require large computational resources. Despite recent progress in parallel and GPU computing, the ability to run fluid flow predictions in real-time is often infeasible. Recently developed machine learning…

Fluid Dynamics · Physics 2021-06-08 Y. van Halder , B. Sanderse , B. Koren

Deep neural networks have been proved efficient for medical image denoising. Current training methods require both noisy and clean images. However, clean images cannot be acquired for many practical medical applications due to naturally…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Dufan Wu , Kuang Gong , Kyungsang Kim , Quanzheng Li

Microscopy image analysis often requires the segmentation of objects, but training data for this task is typically scarce and hard to obtain. Here we propose DenoiSeg, a new method that can be trained end-to-end on only a few annotated…

Computer Vision and Pattern Recognition · Computer Science 2020-06-12 Tim-Oliver Buchholz , Mangal Prakash , Alexander Krull , Florian Jug

Image denoising is a fundamental problem in computational photography, where achieving high perception with low distortion is highly demanding. Current methods either struggle with perceptual quality or suffer from significant distortion.…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Tong Li , Hansen Feng , Lizhi Wang , Zhiwei Xiong , Hua Huang

Flow-Imaging Microscopy (FIM) is commonly used in both academia and industry to characterize subvisible particles (those $\le 25 \mu m$ in size) in protein therapeutics. Pharmaceutical companies are required to record vast volumes of FIM…

Quantitative Methods · Quantitative Biology 2017-09-04 Christopher P. Calderon , Austin L. Daniels , Theodore W. Randolph

The development of neural networks has greatly improved the performance in various computer vision tasks. In the filed of image denoising, convolutional neural network based methods such as DnCNN break through the limits of classical…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Xiaoqi Ma