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Confocal microscopy is essential for histopathologic cell visualization and quantification. Despite its significant role in biology, fluorescence confocal microscopy suffers from the presence of inherent noise during image acquisition.…
The development of voltage-sensitive fluorescent probes suggests fluorescence lifetime as a promising readout for electrical activity in biological systems. Existing approaches fail to achieve the speed and sensitivity required for voltage…
Diffusion and flow-based generative models have shown strong potential for image restoration. However, image denoising under unknown and varying noise conditions remains challenging, because the learned vector fields may become inconsistent…
Deep convolutional neural networks can enhance images taken with small mobile camera sensors and excel at tasks like demoisaicing, denoising and super-resolution. However, for practical use on mobile devices these networks often require too…
We present an ultra-fast, precise, parameter-free method, which we term Deep-STORM, for obtaining super-resolution images from stochastically-blinking emitters, such as fluorescent molecules used for localization microscopy. Deep-STORM uses…
Noise is an inherent issue of low-light image capture, one which is exacerbated on mobile devices due to their narrow apertures and small sensors. One strategy for mitigating noise in a low-light situation is to increase the shutter time of…
Noisy images are a challenge to image compression algorithms due to the inherent difficulty of compressing noise. As noise cannot easily be discerned from image details, such as high-frequency signals, its presence leads to extra bits…
The ability to recover MRI signal from noise is key to achieve fast acquisition, accurate quantification, and high image quality. Past work has shown convolutional neural networks can be used with abundant and paired low and high-SNR images…
Advances in microscopy imaging enable researchers to visualize structures at the nanoscale level thereby unraveling intricate details of biological organization. However, challenges such as image noise, photobleaching of fluorophores, and…
Denoising diffusion models have recently shown impressive results in generative tasks. By learning powerful priors from huge collections of training images, such models are able to gradually modify complete noise to a clean natural image…
Ultrasound images are widespread in medical diagnosis for musculoskeletal, cardiac, and obstetrical imaging due to the efficiency and non-invasiveness of the acquisition methodology. However, the acquired images are degraded by acoustic…
The recent application of deep learning in various areas of medical image analysis has brought excellent performance gains. In particular, technologies based on deep learning in medical image registration can outperform traditional…
Differential dynamic microscopy (DDM) typically relies on movies containing hundreds or thousands of frames to accurately quantify motion in soft matter systems. Using movies much shorter in duration produces noisier and less accurate…
We propose to learn a fully-convolutional network model that consists of a Chain of Identity Mapping Modules and residual on the residual architecture for image denoising. Our network structure possesses three distinctive features that are…
Addressing the issues of severe noise and high frequency structural degradation in visible images under low-light conditions, this paper proposes a Near Infrared (NIR) aided low light image restoration method based on Frequency Decoupled…
We demonstrate a new computational illumination technique that achieves large space-bandwidth-time product, for quantitative phase imaging of unstained live samples in vitro. Microscope lenses can have either large field of view (FOV) or…
Image denoising is a prerequisite for downstream tasks in many fields. Low-dose and photon-counting computed tomography (CT) denoising can optimize diagnostic performance at minimized radiation dose. Supervised deep denoising methods are…
The acquisition of MRI images offers a trade-off in terms of acquisition time, spatial/temporal resolution and signal-to-noise ratio (SNR). Thus, for instance, increasing the time efficiency of MRI often comes at the expense of reduced SNR.…
Image denoising is a typical ill-posed problem due to complex degradation. Leading methods based on normalizing flows have tried to solve this problem with an invertible transformation instead of a deterministic mapping. However, the…
In life sciences, fluorescent labeling techniques are used to study molecular structures and interactions of cells. However, this type of cell imaging has its own limitations, one of which is that the process of staining the cells could be…