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The LIGHT (Linac for Image-Guided Hadron Therapy) project was initiated to develop a modular proton accelerator delivering beam with energies up to 230 MeV for cancer therapy. The machine consists of three different kinds of accelerating…

The Fermilab Linac delivers a variable intensity, 400-MeV beam to the The MuCool Test Area experimental hall via a beam line specifically designed to facilitate measurements of the Linac beam emittance and properties. A 10 m,…

Accelerator Physics · Physics 2013-01-30 F. G. G. Garcia , C. Johnstone , T. Kobilarcik , G. M. Koizumi , C. D. Moore , D. L. Newhart

This study presents a proof-of-concept for a novel Bayesian inverse method in a one-dimensional setting, aimed at proton beam therapy treatment verification. Our methodology is predicated on a hypothetical scenario wherein strategically…

Applications · Statistics 2023-11-21 Alexander M. G. Cox , Laura Hattam , Andreas E. Kyprianou , Tristan Pryer

Purpose: To introduce and evaluate the use of stable distributions as a means of describing the behavior of charged particle pencil beams in a medium, with specific emphasis on proton beam scanning (PBS). Methods: The proton pencil beams of…

Medical Physics · Physics 2018-03-29 Frank Van den Heuvel , Francesca Fiorini , Niek Schreuder , Ben George

Low gain avalanche detectors can measure charged particle fluences with high speed and spatial precision, and are a promising technology for radiation monitoring and dosimetry. A detector has been tested in a medical linac where single…

Instrumentation and Detectors · Physics 2022-02-17 Tommaso Isidori , Patrick McCavana , Brendan McClean , Ronan McNulty , Nicola Minafra , Naomi Raab , Luke Rock , Christophe Royon

A broad-beam-delivery system for heavy-charged-particle radiotherapy often employs multiple collimators and a range-compensating filter, which potentially offer complex beam customization. In treatment planning, it is however difficult for…

Medical Physics · Physics 2012-01-11 Nobuyuki Kanematsu

As the pre-injector of the LHC injector chain, the proton linac at CERN is required to provide a high-intensity (180mA) beam to the Proton Synchrotron Booster. The results of measurements at this intensity will be presented. Furthermore,…

Accelerator Physics · Physics 2007-05-23 C. E. Hill , A. Lombardi , R. Scrivens , M. Vretenar , A. Feschenko , A. Liou

In this paper, a self-consistent transverse beam dynamics framework is demonstrated, that incorporates acceleration into the transverse beam dynamics studies for a proton linac machine. Two focusing schemes are developed and discussed; the…

Accelerator Physics · Physics 2024-03-18 Matthew Southerby , Robert Apsimon

This paper presents the final physics design of the Proton Improvement Plan-II (PIP-II) at Fermilab, focusing on the linear accelerator (Linac) and its beam transfer line. We address the challenges in longitudinal and transverse lattice…

Accelerator Physics · Physics 2024-06-03 Abhishek Pathak , Arun Saini , Eduard Pozdeyev

We present a stabilised finite element method for modelling proton transport in tissue, incorporating both inelastic energy loss and elastic angular scattering. A key innovation is a positivity-preserving formulation that guarantees…

Numerical Analysis · Mathematics 2025-06-03 Ben S. Ashby , Abdalaziz Hamdan , Tristan Pryer

The positrons produced with the electron beam impinging on a conversion target, possess wide energy spectrum and large sweep of the angle of trajectories to the system axis. Accommodation of the positron bunch to the acceptance of an…

Two full rotating gantry with different nozzles (Multipurpose nozzle with MLC, Scanning Dedicated nozzle) with conventional cyclotron system is installed and under commissioning for various proton treatment options at Samsung Medical Center…

A proton pencil beam is associated with a surrounding low-dose envelope, originating from nuclear interactions. It is important for treatment planning systems to accurately model this envelope when performing dose calculations for pencil…

Medical Physics · Physics 2015-11-30 David C. Hall , Anastasia Makarova , Harald Paganetti , Bernard Gottschalk

Next generation online and real-time adaptive radiotherapy workflows require precise particle transport simulations in sub-second times, which is unfeasible with current analytical pencil beam algorithms (PBA) or stochastic Monte Carlo (MC)…

Medical Physics · Physics 2022-02-08 Oscar Pastor-Serrano , Zoltán Perkó

We developed a novel method of creating intensity modulated proton arc therapy (IMPAT) plans that uses computing resources efficiently and may offer a dosimetric benefit for patients with ependymoma or similar tumor geometries. Our IMPAT…

Low Gain Avalanche Detectors (LGADs) are fast silicon sensors with potential for high-resolution proton beam monitoring. In this work, we investigated their response in a 60 MeV proton beam from an AIC-144 cyclotron. Several features of the…

Instrumentation and Detectors · Physics 2025-08-19 A. Bellora , L. Grzanka , R. McNulty , N. Minafra , K. Misan , M. Nessel , T. Nowak , P. Rzeznik , J. Swakon , T. Szollosova

The upcoming Proton Improvement Plan-II (PIP-II), designated for enhancements to the Fermilab accelerator complex, features a new 800 MeV superconducting linac and a Beam Transfer Line (BTL) to transport the beam to the existing Booster…

Accelerator Physics · Physics 2024-06-03 A. Pathak , O. Napoly , J. -F. Ostiguy

Proton beam therapy has been developed to irradiate the tumor with higher precision and dose conformity compared to conventional X-ray irradiation. The dose conformity of this treatment modality may be further improved if narrower proton…

We propose shortcuts to adiabaticity which achieve fast and stable control of the state of a charged particle in an electromagnetic field. In particular we design a non-adiabatic change of the magnetic field strength in a Penning trap which…

Quantum Physics · Physics 2017-03-14 A. Kiely , J. P. L. McGuinness , J. G. Muga , A. Ruschhaupt

Purpose: A Monte Carlo (MC) beam model and its implementation in a clinical treatment planning system (TPS, Varian Eclipse) are presented for a modified ultra-high dose-rate electron FLASH radiotherapy (eFLASH-RT) LINAC. Methods: The gantry…