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Signaling networks are designed to sense an environmental stimulus and adapt to it. We propose and study a minimal model of signaling network that can sense and respond to external stimuli of varying strength in an adaptive manner. The…

Molecular Networks · Quantitative Biology 2010-09-14 Subhadip Raychaudhuri

Molecular networks act as the backbone of cellular activities, providing an {excellent} opportunity to understand the developmental changes in an organism. While network data usually constitute only stationary network graphs, constructing…

Molecular Networks · Quantitative Biology 2016-02-29 Pramod Shinde , Sarika Jalan

We present a model of the central pattern generator (CPG) network that can control gait transitions in hexapod robots in a simple manner based on phase reduction. The CPG network consists of six weakly coupled limit-cycle oscillators, whose…

Adaptation and Self-Organizing Systems · Physics 2025-06-18 Norihisa Namura , Hiroya Nakao

Control is essential to the functioning of any neural system. Indeed, under healthy conditions the brain must be able to continuously maintain a tight functional control between the system's inputs and outputs. One may therefore hypothesise…

Neurons and Cognition · Quantitative Biology 2018-05-29 Emma K. Towlson , Petra E. Vertes , Gang Yan , Yee Lian Chew , Denise S. Walker , William R. Schafer , Albert-Laszlo Barabasi

Particles with ligand-receptor contacts bind and unbind fluctuating "legs" to surfaces, whose fluctuations cause the particle to diffuse. Quantifying the diffusion of such "nanoscale caterpillars" is a challenge, since binding events often…

Soft Condensed Matter · Physics 2022-03-21 Sophie Marbach , Jeana Aojie Zheng , Miranda Holmes-Cerfon

We examine traveling-wave solutions on a regular ring network with one additional long-range link that spans a distance d. The nodes obey the FitzHugh-Nagumo kinetics in the excitable regime. The additional shortcut induces a plethora of…

Adaptation and Self-Organizing Systems · Physics 2015-06-23 Thomas Isele , Benedikt Hartung , Philipp Hövel , Eckehard Schöll

Locomotion is a crucial challenge for legged robots that is addressed "effortlessly" by biological networks abundant in nature, named central pattern generators (CPG). The multitude of CPG network models that have so far become biomimetic…

Neural and Evolutionary Computing · Computer Science 2020-06-09 Ioannis Polykretis , Konstantinos P. Michmizos

Cell migration is a fundamental process underlying the survival and function of both unicellular and multicellular organisms. Crawling motility in eukaryotic cells arises from cyclic protrusion and retraction driven by the cytoskeleton,…

Biological Physics · Physics 2025-11-04 Blaž Ivšić , Igor Weber , Piotr Nowakowski , Ana-Sunčana Smith

How do the same mechanisms that faithfully regenerate complex developmental programs in spite of environmental and genetic perturbations also permit responsiveness to environmental signals, adaptation, and genetic evolution? Using the…

Quantitative Methods · Quantitative Biology 2023-10-20 David J. Jordan , Eric A. Miska

To find out the role of the wiring cost in the organization of the neural network of the nematode \textit{Caenorhapditis elegans} (\textit{C. elegans}), we build the neuronal map of \textit{C. elegans} based on geometrical positions of…

Neurons and Cognition · Quantitative Biology 2009-11-11 Yong-Yeol Ahn , Beom Jun Kim , Hawoong Jeong

An originally chaotic system can be controlled into various periodic dynamics. When it is implemented into a legged robot's locomotion control as a central pattern generator (CPG), sophisticated gait patterns arise so that the robot can…

Artificial Intelligence · Computer Science 2014-09-02 Guanjiao Ren , Weihai Chen , Sakyasingha Dasgupta , Christoph Kolodziejski , Florentin Wörgötter , Poramate Manoonpong

Neuromorphic computing which aims to mimic the collective and emergent behavior of the brain's neurons, synapses, axons, dendrites offers an intriguing, potentially disruptive solution to society's ever-growing computational needs. Although…

Applied Physics · Physics 2021-08-31 Uday S. Goteti , Ivan A. Zaluzhnyy , Shriram Ramanathan , Robert C. Dynes , Alex Frano

Superconducting optoelectronic loop neurons are a class of circuits potentially conducive to networks for large-scale artificial cognition. These circuits employ superconducting components including single-photon detectors, Josephson…

Neural and Evolutionary Computing · Computer Science 2022-10-19 Jeffrey M. Shainline , Bryce A. Primavera , Saeed Khan

Cortical neurons whose activity is recorded in behavioral experiments has been classified into several types such as stimulus-related neurons, delay-period neurons, and reward-related neurons. Moreover, the population activity of neurons…

Neurons and Cognition · Quantitative Biology 2018-11-27 Takuma Tanaka

The centimeter-scale cyborg insects have a potential advantage for application in narrow environments where humans cannot operate. To realize such tasks, researchers have developed a small printed-circuit-board (PCB) which an insect can…

Robotics · Computer Science 2024-10-11 Kazuki Kai , Le Duc Long , Hirotaka Sato

In our previous work, we studied an interconnected bursting neuron model for insect locomotion, and its corresponding phase oscillator model, which at high speed can generate stable tripod gaits with three legs off the ground simultaneously…

Dynamical Systems · Mathematics 2018-07-16 Zahra Aminzare , Philip Holmes

Deep phenotyping is an emerging conceptual paradigm and experimental approach that seeks to measure many aspects of phenotypes and link them to understand the underlying biology. Successful deep phenotyping has mostly been applied in…

Quantitative Methods · Quantitative Biology 2019-04-03 Nan Xu , Dhaval S. Patel , Hang Lu

C. elegans is commonly used in neuroscience for behaviour analysis because of it's compact nervous system with well-described connectivity. Localizing the animal and distinguishing between its head and tail are important tasks to track the…

Computer Vision and Pattern Recognition · Computer Science 2020-01-14 Mansi Ranjit Mane , Aniket Anand Deshmukh , Adam J. Iliff

In recent years, locomotion mechanisms exhibited by vertebrate animals have been the inspiration for the improvement in the performance of robotic systems. These mechanisms include the adaptability of their locomotion to any change…

Neural and Evolutionary Computing · Computer Science 2022-07-04 Pablo Lopez-Osorio , Alberto Patino-Saucedo , Juan P. Dominguez-Morales , Horacio Rostro-Gonzalez , Fernando Perez-Peña

Learning interpretable representations of neural dynamics at a population level is a crucial first step to understanding how observed neural activity relates to perception and behavior. Models of neural dynamics often focus on either…

Machine Learning · Statistics 2025-01-13 Noga Mudrik , Yenho Chen , Eva Yezerets , Christopher J. Rozell , Adam S. Charles