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Utilizing clinical texts in survival analysis is difficult because they are largely unstructured. Current automatic extraction models fail to capture textual information comprehensively since their labels are limited in scope. Furthermore,…

Computation and Language · Computer Science 2021-05-04 Hyun Gi Lee , Evan Sholle , Ashley Beecy , Subhi Al'Aref , Yifan Peng

Background: Lung cancer was known as primary cancers and the survival rate of cancer is about 15%. Early detection of lung cancer is the leading factor in survival rate. All symptoms (features) of lung cancer do not appear until the cancer…

Artificial Intelligence · Computer Science 2016-01-26 Mitra Montazeri , Mahdieh Soleymani Baghshah , Ahmad Enhesari

In medical research, it is often needed to obtain subgroups with heterogeneous survivals, which have been predicted from a prognostic factor. For this purpose, a binary split has often been used once or recursively; however, binary…

Applications · Statistics 2014-11-04 Soo-Heang Eo , Hyo Jeong Kang , Seung-Mo Hong , HyungJun Cho

Survival analysis is widely used as a technique to model time-to-event data when some data is censored, particularly in healthcare for predicting future patient risk. In such settings, survival models must be both accurate and interpretable…

Machine Learning · Computer Science 2024-04-24 Mike Van Ness , Madeleine Udell

Kidney stones are a common and debilitating health issue, and genetic factors play a crucial role in determining susceptibility. While Genome-Wide Association Studies (GWAS) have identified numerous single nucleotide polymorphisms (SNPs)…

Genomics · Quantitative Biology 2024-12-24 Amr Salem , Anirban Mondal

Hip fractures are a leading cause of death and disability among older adults. Hip fractures are also the most commonly missed diagnosis on pelvic radiographs. Computer-Aided Diagnosis (CAD) algorithms have shown promise for helping…

We propose a simulation-optimization-based methodology to improve the way that organ transplant offers are made to potential recipients. Our policy can be applied to all types of organs, is implemented starting at the local level, is…

Medical Physics · Physics 2022-12-01 Ignacio Erazo , David Goldsman , Pinar Keskinocak , Joel Sokol

In this manuscript we analyze a data set containing information on children with Hodgkin Lymphoma (HL) enrolled on a clinical trial. Treatments received and survival status were collected together with other covariates such as demographics…

Quantitative Methods · Quantitative Biology 2021-03-29 Cédric Beaulac , Jeffrey S. Rosenthal , Qinglin Pei , Debra Friedman , Suzanne Wolden , David Hodgson

Globally, chronic liver disease continues to be a major health concern that requires precise predictive models for prompt detection and treatment. Using the Indian Liver Patient Dataset (ILPD) from the University of California at Irvine's…

Machine Learning · Computer Science 2024-12-31 Anand Karna , Naina Khan , Rahul Rauniyar , Prashant Giridhar Shambharkar

Multiple indications of disease progression found in a cancer patient by loco-regional relapse, distant metastasis and death. Early identification of these indications is necessary to change the treatment strategy. Biomarkers play an…

Applications · Statistics 2021-07-23 Atanu Bhattacharjee , Gajendra K. Vishwakarma , Souvik Banerjee

In medicine, survival analysis studies the time duration to events of interest such as mortality. One major challenge is how to deal with multiple competing events (e.g., multiple disease diagnoses). In this work, we propose a…

Machine Learning · Computer Science 2022-06-29 Zifeng Wang , Jimeng Sun

The study of disparities in the liver transplantation process may focus on quantifying causal effects, particularly the average, direct, or indirect effects of various social determinants of health on being listed as a candidate for…

Lung transplantation remains the only viable treatment option for the majority of patients with advanced lung diseases. However, 5-year post-transplant survival rates remain low primarily secondary to chronic rejection. Novel insights from…

Genomics · Quantitative Biology 2013-08-12 Wei Zhang , Tong Zhou , Shwu-Fan Ma , Robert F. Machado , Sangeeta M. Bhorade , Joe G. N. Garcia

In this study, we investigated the application of bio-inspired optimization algorithms, including Genetic Algorithm, Particle Swarm Optimization, and Whale Optimization Algorithm, for feature selection in chronic disease prediction. The…

Neural and Evolutionary Computing · Computer Science 2024-01-12 Abeer Dyoub , Ivan Letteri

Aging clocks aim to estimate biological age, a measure of physiological state distinct from chronological age, from observable biomarkers, and are widely used for health assessment and disease analysis. DNA methylation is a particularly…

Machine Learning · Computer Science 2026-05-11 Qing Qing , Xikun Zhang , Zhongyuan Zhang , Jiarui Liu , Xingtong Yu , Xiaotao Shen , Ziqi Xu , Qixin Zhang , Zhe Wang , Renqiang Luo

In barter exchanges, participants swap goods with one another without exchanging money; exchanges are often facilitated by a central clearinghouse, with the goal of maximizing the aggregate quality (or number) of swaps. Barter exchanges are…

Artificial Intelligence · Computer Science 2020-10-26 Duncan C McElfresh , Michael Curry , Tuomas Sandholm , John P Dickerson

This study explores the potential of utilizing administrative claims data, combined with advanced machine learning and deep learning techniques, to predict the progression of Chronic Kidney Disease (CKD) to End-Stage Renal Disease (ESRD).…

Machine Learning · Computer Science 2024-10-28 Yubo Li , Saba Al-Sayouri , Rema Padman

Colorectal liver metastases (CLM) significantly impact colon cancer patients, influencing survival based on systemic chemotherapy response. Traditional methods like tumor grading scores (e.g., tumor regression grade - TRG) for prognosis…

We considered the systematics of $\alpha$-decay (AD) half-life (HL) of super-heavy nuclei versus the decay energy and the total $\alpha$-kinetic energy. We calculated the HL using the experimental Q_{$\alpha$} values. The computed…

Nuclear Theory · Physics 2017-06-28 S. S. Hosseini , H. Hassanabadi

The morphometry of a kidney tumor revealed by contrast-enhanced Computed Tomography (CT) imaging is an important factor in clinical decision making surrounding the lesion's diagnosis and treatment. Quantitative study of the relationship…