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Kidney transplantation is the preferred treatment for people suffering from end-stage renal disease. Successful kidney transplants still fail over time, known as graft failure; however, the time to graft failure, or graft survival time, can…

Machine Learning · Computer Science 2022-11-07 Zhipeng Huang , Kevin S. Xu

A kidney transplant can improve the life expectancy and quality of life of patients with end-stage renal failure. Even more patients could be helped with a transplant if the rate of kidneys that are discarded and not transplanted could be…

The burgeoning need for kidney transplantation mandates immediate attention. Mismatch of deceased donor-recipient kidney leads to post-transplant death. To ensure ideal kidney donor-recipient match and minimize post-transplant deaths, the…

Computers and Society · Computer Science 2019-08-22 Ehsan Khan , Avishek Choudhury , Amy L Friedman , Daehan Won

Kidney transplantation is the most effective renal replacement therapy for end stage renal disease patients. With the severe shortage of kidney supplies and for the clinical effectiveness of transplantation, patient's life expectancy post…

Methodology · Statistics 2023-10-19 Ge Zhao , Yanyuan Ma , Huazhen Lin , Yi Li

An accurate model of patient-specific kidney graft survival distributions can help to improve shared-decision making in the treatment and care of patients. In this paper, we propose a deep learning method that directly models the survival…

Machine Learning · Computer Science 2017-05-30 Margaux Luck , Tristan Sylvain , Héloïse Cardinal , Andrea Lodi , Yoshua Bengio

Kidney transplantation is the preferred treatment for end-stage renal disease, yet the scarcity of donors and inefficiencies in allocation systems create major bottlenecks, resulting in prolonged wait times and alarming mortality rates.…

Computer Science and Game Theory · Computer Science 2024-10-15 Sean Berry , Berk Gorgulu , Sait Tunc , Mucahit Cevik , Matthew J Ellis

In observational studies of survival time featuring a binary time-dependent treatment, the hazard ratio (an instantaneous measure) is often used to represent the treatment effect. However, investigators are often more interested in the…

Methodology · Statistics 2020-05-21 Yun Li , Douglas E. Schaubel , Kevin He

This paper presents a comprehensive review of the last two decades of research on Kidney Exchange Programs (KEPs), systematically categorizing and classifying key contributions to provide readers with a structured understanding of…

Artificial Intelligence · Computer Science 2025-02-13 Shayan Sharifi

Liver allograft failure occurs in approximately 20% of liver transplant recipients within five years post-transplant, leading to mortality or the need for retransplantation. Providing an accurate and interpretable model for individualized…

Machine Learning · Computer Science 2024-08-13 Xiang Gao , Michael Cooper , Maryam Naghibzadeh , Amirhossein Azhie , Mamatha Bhat , Rahul G. Krishnan

Kidney transplantation is the best treatment for end-stage renal failure patients. The predominant method used for kidney quality assessment is the Cox regression-based, kidney donor risk index. A machine learning method may provide…

Machine Learning · Computer Science 2020-12-08 Eric S. Pahl , W. Nick Street , Hans J. Johnson , Alan I. Reed

Kidney Exchange Programs (KEPs) promote access to living donor trans- plantation for patients suffering from end stage renal disease. The HLA compatibility between transplant recipients and donors plays an important role when solving the…

Optimization and Control · Mathematics 2025-10-17 Valentina Peralta Clarke , Hans de Ferrante , Francisco Perez Galarce , Joris van de Klundert

Liver transplantation is a life-saving procedure for patients with end-stage liver disease. There are two main challenges in liver transplant: finding the best matching patient for a donor and ensuring transplant equity among different…

Machine Learning · Computer Science 2024-03-04 Can Li , Xiaoqian Jiang , Kai Zhang

Five year post-transplant survival rate is an important indicator on quality of care delivered by kidney transplant centers in the United States. To provide a fair assessment of each transplant center, an effect that represents the…

Applications · Statistics 2017-03-13 Lanfeng Pan , Yehua Li , Kevin He , Yanming Li , Yi Li

Kidney exchanges are organized markets where patients swap willing but incompatible donors. In the last decade, kidney exchanges grew from small and regional to large and national---and soon, international. This growth results in more lives…

Artificial Intelligence · Computer Science 2016-12-19 John P. Dickerson , Aleksandr M. Kazachkov , Ariel D. Procaccia , Tuomas Sandholm

Time-to-event prediction, e.g. cancer survival analysis or hospital length of stay, is a highly prominent machine learning task in medical and healthcare applications. However, only a few interpretable machine learning methods comply with…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Hubert Baniecki , Bartlomiej Sobieski , Patryk Szatkowski , Przemyslaw Bombinski , Przemyslaw Biecek

Deep-learning techniques, particularly the transformer model, have shown great potential in enhancing the prediction performance of longitudinal health records. While previous methods have mainly focused on fixed-time risk prediction,…

Machine Learning · Computer Science 2024-05-03 Moshe Zisser , Dvir Aran

Liver transplant is an essential therapy performed for severe liver diseases. The fact of scarce liver resources makes the organ assigning crucial. Model for End-stage Liver Disease (MELD) score is a widely adopted criterion when making…

Artificial Intelligence · Computer Science 2023-02-21 Sirui Ding , Ruixiang Tang , Daochen Zha , Na Zou , Kai Zhang , Xiaoqian Jiang , Xia Hu

Liver transplant can be a life-saving procedure for patients with end-stage liver disease. With the introduction of modern immunosuppressive therapies, short-term survival has significantly improved. However, long-term survival has not…

Quantitative Methods · Quantitative Biology 2024-11-28 Julia Bruner , Kyle Adams , Skylar Grey , Mahya Aghaee , Sergio Duarte , Ali Zarrinpar , Helen Moore

Liver transplantation continues to be the gold standard for treating patients with end-stage liver diseases. However, despite the huge success of liver transplantation in improving patient outcomes, long term graft survival continues to be…

Other Quantitative Biology · Quantitative Biology 2023-06-02 Raja Al-Bahou , Julia Bruner , Helen Moore , Ali Zarrinpar

Dynamic predictions of survival outcomes are of great interest to physicians and patients, since such predictions are useful elements of clinical decision-making. Joint modelling of longitudinal and survival data has been increasingly used…

Applications · Statistics 2019-06-10 Ozgur Asar , Marie-Cecile Fournier , Etienne Dantan
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