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Related papers: GenoML: Automated Machine Learning for Genomics

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Large language models (LLMs) have shown growing promise in biomedical research, particularly for knowledge-driven interpretation tasks. However, their ability to reliably reason from gene-level knowledge to functional understanding, a core…

Genomics · Quantitative Biology 2026-05-25 Xiaohan Huang , Meng Xiao , Chuan Qin , Qingqing Long , Jinmiao Chen , Yuanchun Zhou , Hengshu Zhu

The advancements in artificial intelligence in recent years, such as Large Language Models (LLMs), have fueled expectations for breakthroughs in genomic foundation models (GFMs). The code of nature, hidden in diverse genomes since the very…

Genomics · Quantitative Biology 2024-10-03 Heng Yang , Jack Cole , Ke Li

This work describes the selection approach and analysis of existing AutoML frameworks regarding their capability of a) incorporating Quantum Machine Learning (QML) algorithms into this automated solving approach of the AutoML framing and b)…

Machine Learning · Computer Science 2023-10-09 Dennis Klau , Marc Zöller , Christian Tutschku

Correlation among the observations in high-dimensional regression modeling can be a major source of confounding. We present a new open-source package, plmmr, to implement penalized linear mixed models in R. This R package estimates…

Computation · Statistics 2026-05-13 Tabitha K. Peter , Anna C. Reisetter , Yujing Lu , Oscar A. Rysavy , Patrick J. Breheny

Lean processes focus on doing only necessery things in an efficient way. Artificial intelligence and Machine Learning offer new opportunities to optimizing processes. The presented approach demonstrates an improvement of the test process by…

Software Engineering · Computer Science 2019-06-10 Alexander Poth , Quirin Beck , Andreas Riel

A common claim of evolutionary computation methods is that they can achieve good results without the need for human intervention. However, one criticism of this is that there are still hyperparameters which must be tuned in order to achieve…

Neural and Evolutionary Computing · Computer Science 2021-02-11 Benjamin Patrick Evans , Bing Xue , Mengjie Zhang

This work introduces SwarmRL, a Python package designed to study intelligent active particles. SwarmRL provides an easy-to-use interface for developing models to control microscopic colloids using classical control and deep reinforcement…

MPAgenomics, standing for multi-patients analysis (MPA) of genomic markers, is an R-package devoted to: (i) efficient segmentation, and (ii) genomic marker selection from multi-patient copy number and SNP data profiles. It provides wrappers…

Quantitative Methods · Quantitative Biology 2014-01-21 Quentin Grimonprez , Alain Celisse , Meyling Cheok , Martin Figeac , Guillemette Marot

Machine learning (ML) is becoming increasingly crucial in many fields of engineering but has not yet played out its full potential in bioprocess engineering. While experimentation has been accelerated by increasing levels of lab automation,…

In this paper, we present the first-of-its-kind machine learning (ML) system, called AI Programmer, that can automatically generate full software programs requiring only minimal human guidance. At its core, AI Programmer uses genetic…

Artificial Intelligence · Computer Science 2017-09-19 Kory Becker , Justin Gottschlich

Recent advancements in Large Language Models (LLMs) have led to high-quality Machine-Generated Text (MGT), giving rise to countless new use cases and applications. However, easy access to LLMs is posing new challenges due to misuse. To…

Computation and Language · Computer Science 2024-04-15 Areg Mikael Sarvazyan , José Ángel González , Marc Franco-Salvador

Gene assembly is an important step in functional analysis of shotgun metagenomic data. Nonetheless, strain aware assembly remains a challenging task, as current assembly tools often fail to distinguish among strain variants or require…

Quantitative Methods · Quantitative Biology 2015-10-15 I. Gregor , A. Schönhuth , A. C. McHardy

Genetic Programming is an evolutionary algorithm that generates computer programs, or mathematical expressions, to solve complex problems. In this Guide, we demonstrate how to use Genetic Programming to develop surrogate models to mitigate…

The goal of automated machine learning (AutoML) is to reduce trial and error when doing machine learning (ML). Although AutoML methods for classification are able to deal with data imperfections, such as outliers, multiple scales and…

Machine Learning · Computer Science 2026-02-03 Marcos L. P. Bueno , Joaquin Vanschoren

This paper introduces PyGAD, an open-source easy-to-use Python library for building the genetic algorithm. PyGAD supports a wide range of parameters to give the user control over everything in its life cycle. This includes, but is not…

Neural and Evolutionary Computing · Computer Science 2021-06-14 Ahmed Fawzy Gad

The integration of machine learning with blockchain technology has witnessed increasing interest, driven by the vision of decentralized, secure, and transparent AI services. In this context, we introduce opML (Optimistic Machine Learning on…

Cryptography and Security · Computer Science 2024-02-06 KD Conway , Cathie So , Xiaohang Yu , Kartin Wong

Predicting gene function from its DNA sequence is a fundamental challenge in biology. Many deep learning models have been proposed to embed DNA sequences and predict their enzymatic function, leveraging information in public databases…

There has been an explosion in interest in machine learning (ML) in recent years due to its applications to science and engineering. However, as ML techniques have advanced, tools for explaining and visualizing novel ML algorithms have…

Machine Learning · Computer Science 2023-11-16 Alec Helbling , Duen Horng Chau

Summary: With the rapid development of long-read sequencing technologies, the era of individual complete genomes is approaching. We have developed wgatools, a cross-platform, ultrafast toolkit that supports a range of whole genome alignment…

Genomics · Quantitative Biology 2025-04-01 Wenjie Wei , Songtao Gui , Jian Yang , Erik Garrison , Jianbing Yan , Hai-Jun Liu

We explore trust in a relatively new area of data science: Automated Machine Learning (AutoML). In AutoML, AI methods are used to generate and optimize machine learning models by automatically engineering features, selecting models, and…

Machine Learning · Computer Science 2020-01-22 Jaimie Drozdal , Justin Weisz , Dakuo Wang , Gaurav Dass , Bingsheng Yao , Changruo Zhao , Michael Muller , Lin Ju , Hui Su