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The segmentation of prostate whole gland and transition zone in Diffusion Weighted MRI (DWI) are the first step in designing computer-aided detection algorithms for prostate cancer. However, variations in MRI acquisition parameters and…

Image and Video Processing · Electrical Eng. & Systems 2020-10-29 Saman Motamed , Isha Gujrathi , Dominik Deniffel , Anton Oentoro , Masoom A. Haider , Farzad Khalvati

Real-time localization of prostate gland in trans-rectal ultrasound images is a key technology that is required to automate the ultrasound guided prostate biopsy procedures. In this paper, we propose a new deep learning based approach which…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Ahmet Tuysuzoglu , Jeremy Tan , Kareem Eissa , Atilla P. Kiraly , Mamadou Diallo , Ali Kamen

Recent studies have demonstrated the diagnostic and prognostic values of global glomerulosclerosis (GGS) in IgA nephropathy, aging, and end-stage renal disease. However, the fine-grained quantitative analysis of multiple GGS subtypes (e.g.,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-02 Yuzhe Lu , Haichun Yang , Zuhayr Asad , Zheyu Zhu , Tianyuan Yao , Jiachen Xu , Agnes B. Fogo , Yuankai Huo

Medical imaging based prostate cancer diagnosis procedure uses intra-operative transrectal ultrasound (TRUS) imaging to visualize the prostate shape and location to collect tissue samples. Correct tissue sampling from prostate requires…

Computer Vision and Pattern Recognition · Computer Science 2019-03-22 M. S. Hossain , A. P. Paplinski , J. M. Betts

Osteosarcoma is the most common primary malignant bone tumor, which has high mortality due to easy lung metastasis. Osteosarcoma is a highly anaplastic, pleomorphic tumor with a variety of tumor cell morphology, including fusiform, oval,…

Medical Physics · Physics 2021-01-27 Yu Fu

Cancer grade is a critical clinical criterion that can be used to determine the degree of cancer malignancy. Revealing the condition of the glands, a precise gland segmentation can assist in a more effective cancer grade classification. In…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Yijie Zhu , Shan E Ahmed Raza

Convolutional Neural Networks (CNNs) have been used for automated detection of prostate cancer where Area Under Receiver Operating Characteristic (ROC) curve (AUC) is usually used as the performance metric. Given that AUC is not…

Image and Video Processing · Electrical Eng. & Systems 2019-11-06 Khashayar Namdar , Isha Gujrathi , Masoom A. Haider , Farzad Khalvati

Automatic diagnosis of malignant prostate cancer patients from mpMRI has been studied heavily in the past years. Model interpretation and domain drift have been the main road blocks for clinical utilization. As an extension from our…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Weiwei Zong , Eric Carver , Simeng Zhu , Eric Schaff , Daniel Chapman , Joon Lee , Hassan Bagher Ebadian , Indrin Chetty , Benjamin Movsas , Winston Wen , Tarik Alafif , Xiangyun Zong

Determining the primary site of origin for metastatic tumors is one of the open problems in cancer care because the efficacy of treatment often depends on the cancer tissue of origin. Classification methods that can leverage tumor genomic…

Genomics · Quantitative Biology 2019-11-19 Alena Harley

Colorectal cancer (CRC) remains a significant cause of cancer-related mortality, despite the widespread implementation of prophylactic initiatives aimed at detecting and removing precancerous polyps. Although screening effectively reduces…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Ahmed Rahu , Brian Shula , Brandon Combs , Aqsa Sultana , Surendra P. Singh , Vijayan K. Asari , Derrick Forchetti

Artificial intelligence (AI) is becoming a clinical tool for prostate pathology, but generalization across variations in sample preparation and preservation over prolonged time periods remains poorly understood. We evaluated GleasonAI, an…

Prostate cancer, the second most prevalent male malignancy, requires advanced diagnostic tools. We propose an explainable AI system combining BERT (for textual clinical notes) and Random Forest (for numerical lab data) through a novel…

Breast cancer is the most common cancer in the world and the most prevalent cause of death among women worldwide. Nevertheless, it is also one of the most treatable malignancies if detected early. In this paper, a deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2021-12-23 Hussin Ragb , Redha Ali , Elforjani Jera , Nagi Buaossa

Survival outcomes are common in comparative effectiveness studies and require unique handling because they are usually incompletely observed due to right-censoring. A ``once for all'' approach for causal inference with survival outcomes…

Methodology · Statistics 2021-12-21 Shuxi Zeng , Fan Li , Liangyuan Hu , Fan Li

Automatic prostate segmentation is an important step in computer-aided diagnosis of prostate cancer and treatment planning. Existing methods of prostate segmentation are based on deep learning models which have a large size and lack of…

Early diagnosis of prostate cancer is crucial for efficient treatment. Multi-parametric Magnetic Resonance Images (mp-MRI) are widely used for lesion detection. The Prostate Imaging Reporting and Data System (PI-RADS) has standardized…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Camille Ruppli , Pietro Gori , Roberto Ardon , Isabelle Bloch

Radiotherapy treatment for prostate cancer relies on computed tomography (CT) and/or magnetic resonance imaging (MRI) for segmentation of target volumes and organs at risk (OARs). Manual segmentation of these volumes is regarded as the gold…

We hypothesize that anatomical priors can be viable mediums to infuse domain-specific clinical knowledge into state-of-the-art convolutional neural networks (CNN) based on the U-Net architecture. We introduce a probabilistic population…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Anindo Saha , Matin Hosseinzadeh , Henkjan Huisman

Standard of care diagnostic procedure for suspected skin cancer is microscopic examination of hematoxylin \& eosin stained tissue by a pathologist. Areas of high inter-pathologist discordance and rising biopsy rates necessitate higher…

Segmentation of histopathology sections is an ubiquitous requirement in digital pathology and due to the large variability of biological tissue, machine learning techniques have shown superior performance over standard image processing…

Computer Vision and Pattern Recognition · Computer Science 2017-10-11 Philipp Kainz , Michael Pfeiffer , Martin Urschler