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Despite considerable progress in developing artificial intelligence (AI) algorithms for prostate cancer detection from whole slide images, the clinical applicability of these models remains limited due to variability in pathological…

Tissues and Organs · Quantitative Biology 2024-06-12 T. J. Hart , Chloe Engler Hart , Spencer Hopson , Paul M. Urie , Dennis Della Corte

The large number of trainable parameters of deep neural networks renders them inherently data hungry. This characteristic heavily challenges the medical imaging community and to make things even worse, many imaging modalities are ambiguous…

Neural and Evolutionary Computing · Computer Science 2017-11-29 Simon Kohl , David Bonekamp , Heinz-Peter Schlemmer , Kaneschka Yaqubi , Markus Hohenfellner , Boris Hadaschik , Jan-Philipp Radtke , Klaus Maier-Hein

Oral cancer ranks among the most prevalent cancers globally, with a particularly high mortality rate in regions lacking adequate healthcare access. Early diagnosis is crucial for reducing mortality; however, challenges persist due to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Akshay Bhagwan Sonawane , Lena D. Swamikannan , Lakshman Tamil

The size and geometry of the prostate are known to be pivotal quantities used by clinicians to assess the condition of the gland during prostate cancer screening. As an alternative to palpation, an increasing number of methods for…

Computer Vision and Pattern Recognition · Computer Science 2009-10-01 Robert Sheng Xu , Oleg Michailovich , Magdy Salama

Skin cancer holds the highest incidence rate among all cancers globally. The importance of early detection cannot be overstated, as late-stage cases can be lethal. Classifying skin lesions, however, presents several challenges due to the…

Machine Learning · Computer Science 2023-06-14 Asim Naveed , Syed S. Naqvi , Tariq M. Khan , Imran Razzak

Although melanoma occurs more rarely than several other skin cancers, patients' long term survival rate is extremely low if the diagnosis is missed. Diagnosis is complicated by a high discordance rate among pathologists when distinguishing…

Current deep learning approaches for prostate cancer lesion segmentation achieve limited performance, with Dice scores of 0.32 or lower in large patient cohorts. To address this limitation, we investigate synthetic correlated diffusion…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Jarett Dewbury , Chi-en Amy Tai , Alexander Wong

Gastric cancer is the fifth most common cancer in the world. At the same time, it is also the fourth most deadly cancer. Early detection of cancer exists as a guide for the treatment of gastric cancer. Nowadays, computer technology has…

Image and Video Processing · Electrical Eng. & Systems 2022-05-26 Weiming Hu , Haoyuan Chen , Wanli Liu , Xiaoyan Li , Hongzan Sun , Xinyu Huang , Marcin Grzegorzek , Chen Li

Tremor is a key diagnostic feature of Parkinson's Disease (PD), Essential Tremor (ET), and other central nervous system (CNS) disorders. Clinicians or trained raters assess tremor severity with TETRAS scores by observing patients. Lacking…

Computer Vision and Pattern Recognition · Computer Science 2021-05-05 Li Zhang , Vijay Yadav , Vidya Koesmahargyo , Anzar Abbas , Isaac Galatzer-Levy

This study focuses on comparing deep learning methods for the segmentation and quantification of uncertainty in prostate segmentation from MRI images. The aim is to improve the workflow of prostate cancer detection and diagnosis. Seven…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Pablo Cesar Quihui-Rubio , Daniel Flores-Araiza , Gilberto Ochoa-Ruiz , Miguel Gonzalez-Mendoza , Christian Mata

In computational pathology, cancer grading has been mainly studied as a categorical classification problem, which does not utilize the ordering nature of cancer grades such as the higher the grade is, the worse the cancer is. To incorporate…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Ju Cheon Lee , Keunho Byeon , Boram Song , Kyungeun Kim , Jin Tae Kwak

Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel

Prostate cancer is a highly prevalent cancer and ranks as the second leading cause of cancer-related deaths in men globally. Recently, the utilization of multi-modality transrectal ultrasound (TRUS) has gained significant traction as a…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Hong Wu , Juan Fu , Hongsheng Ye , Yuming Zhong , Xuebin Zou , Jianhua Zhou , Yi Wang

Transrectal biopsies under 2D ultrasound (US) control are the current clinical standard for prostate cancer diagnosis. The isoechogenic nature of prostate carcinoma makes it necessary to sample the gland systematically, resulting in a low…

Computer Vision and Pattern Recognition · Computer Science 2011-07-11 Michael Baumann , Pierre Mozer , Vincent Daanen , Jocelyne Troccaz

Prostate cancer is a leading cause of mortality in men, yet interpretation of T2-weighted prostate MRI remains challenging due to subtle and heterogeneous lesions. We developed an interpretable framework for automatic cancer detection using…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Vahid Monfared , Mohammad Hadi Gharib , Ali Sabri , Maryam Shahali , Farid Rashidi , Amit Mehta , Reza Rawassizadeh

This paper proposes a two-stage segmentation model, variable-input based uncertainty measures and an uncertainty-guided post-processing method for prostate segmentation on 3D magnetic resonance images (MRI). The two-stage model was based on…

Computer Vision and Pattern Recognition · Computer Science 2019-03-07 Huitong Pan , Yushan Feng , Quan Chen , Craig Meyer , Xue Feng

Molecular phenotyping by gene expression profiling is common in contemporary cancer research and in molecular diagnostics. However, molecular profiling remains costly and resource intense to implement, and is just starting to be introduced…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Philippe Weitz , Yinxi Wang , Kimmo Kartasalo , Lars Egevad , Johan Lindberg , Henrik Grönberg , Martin Eklund , Mattias Rantalainen

Machine learning (ML) is a branch of Artificial Intelligence (AI) where computers analyze data and find patterns in the data. The study focuses on the detection of metastatic cancer using ML. Metastatic cancer is the point where the cancer…

Artificial Intelligence · Computer Science 2023-09-20 Bliss Singhal , Fnu Pooja

Using histopathological images to automatically classify cancer is a difficult task for accurately detecting cancer, especially to identify metastatic cancer in small image patches obtained from larger digital pathology scans. Computer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-16 Guanwen Qiu , Xiaobing Yu , Baolin Sun , Yunpeng Wang , Lipei Zhang

Prostate Cancer is one of the most frequently occurring cancers in men, with a low survival rate if not early diagnosed. PI-RADS reading has a high false positive rate, thus increasing the diagnostic incurred costs and patient discomfort.…