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Counterfactual thinking is a crucial yet challenging topic for artificial intelligence to learn knowledge from data and ultimately improve performance for new scenarios. Many research works, including the Potential Outcome Model (POM) and…

Artificial Intelligence · Computer Science 2026-02-24 Mingyu Kang , Duxin Chen , Ziyuan Pu , Jianxi Gao , Wenwu Yu

The classification of medical images is a pivotal aspect of disease diagnosis, often enhanced by deep learning techniques. However, traditional approaches typically focus on unimodal medical image data, neglecting the integration of diverse…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Jun-En Ding , Chien-Chin Hsu , Chi-Hsiang Chu , Shuqiang Wang , Feng Liu

Medical images constitute a source of information essential for disease diagnosis, treatment and follow-up. In addition, due to its patient-specific nature, imaging information represents a critical component required for advancing…

Computer Vision and Pattern Recognition · Computer Science 2016-06-10 Dorin Comaniciu , Klaus Engel , Bogdan Georgescu , Tommaso Mansi

Deep generative models have demonstrated remarkable success in medical image synthesis. However, ensuring conditioning faithfulness and high-quality synthetic images for direct or counterfactual generation remains a challenge. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Fangrui Huang , Alan Wang , Binxu Li , Bailey Trang , Ridvan Yesiloglu , Tianyu Hua , Wei Peng , Ehsan Adeli

Magnetic resonance spectroscopic imaging is a widely available imaging modality that can non-invasively provide a metabolic profile of the tissue of interest, yet is challenging to integrate clinically. One major reason is the expensive,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-11 John LaMaster , Dhritiman Das , Florian Kofler , Jason Crane , Yan Li , Tobias Lasser , Bjoern H Menze

To date, several automated strategies for identification/segmentation of Multiple Sclerosis (MS) lesions with the use of Magnetic Resonance Imaging (MRI) have been presented, but they are outperformed by human experts, from whom they act…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Giuseppe Placidi , Luigi Cinque , Daniela Iacoviello , Filippo Mignosi , Matteo Polsinelli

We present a didactic introduction to spectral Dynamic Causal Modelling (DCM), a Bayesian state-space modelling approach used to infer effective connectivity from non-invasive neuroimaging data. Spectral DCM is currently the most widely…

Neurons and Cognition · Quantitative Biology 2023-09-07 Leonardo Novelli , Karl Friston , Adeel Razi

Pre-trained segmentation models are a powerful and flexible tool for segmenting images. Recently, this trend has extended to medical imaging. Yet, often these methods only produce a single prediction for a given image, neglecting inherent…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Benjamin Towle , Xin Chen , Ke Zhou

Cause-effect relationships are typically evaluated by comparing outcome responses to binary treatment values, representing two arms of a hypothetical randomized controlled trial. However, in certain applications, treatments of interest are…

Methodology · Statistics 2022-06-15 Razieh Nabi , Todd McNutt , Ilya Shpitser

Reasoning, a crucial aspect of NLP research, has not been adequately addressed by prevailing models including Large Language Model. Conversation reasoning, as a critical component of it, remains largely unexplored due to the absence of a…

Computation and Language · Computer Science 2024-01-17 Hang Chen , Bingyu Liao , Jing Luo , Wenjing Zhu , Xinyu Yang

Magnetic resonance imaging (MRI) is central to the diagnosis of multiple sclerosis, where the identification of biomarkers such as the central vein sign benefits from high-resolution images. However, most clinical brain MRI scans are…

Optimization and Control · Mathematics 2026-03-05 Matteo Cannas , Alice Mariottini , Luca Massacesi , Federica Porta , Simone Rebegoldi , Andrea Sebastiani

Multiple sclerosis is an inflammatory autoimmune demyelinating disease that is characterized by lesions in the central nervous system. Typically, magnetic resonance imaging (MRI) is used for tracking disease progression. Automatic image…

Image and Video Processing · Electrical Eng. & Systems 2020-08-06 Nils Gessert , Julia Krüger , Roland Opfer , Ann-Christin Ostwaldt , Praveena Manogaran , Hagen H. Kitzler , Sven Schippling , Alexander Schlaefer

Synthetic datasets generated by structural causal models (SCMs) are commonly used for benchmarking causal structure learning algorithms. However, the variances and pairwise correlations in SCM data tend to increase along the causal…

Machine Learning · Computer Science 2025-03-18 Weronika Ormaniec , Scott Sussex , Lars Lorch , Bernhard Schölkopf , Andreas Krause

Dynamic structural causal models (SCMs) are a powerful framework for reasoning in dynamic systems about direct effects which measure how a change in one variable affects another variable while holding all other variables constant. The…

Artificial Intelligence · Computer Science 2024-02-16 Simon Ferreira , Charles K. Assaad

Reconstructing medical images from partial measurements is an important inverse problem in Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). Existing solutions based on machine learning typically train a model to directly map…

Image and Video Processing · Electrical Eng. & Systems 2022-06-17 Yang Song , Liyue Shen , Lei Xing , Stefano Ermon

Artificial intelligence is increasingly leveraged across various domains to automate decision-making processes that significantly impact human lives. In medical image analysis, deep learning models have demonstrated remarkable performance.…

Machine Learning · Computer Science 2025-07-28 Julia Siekiera , Stefan Kramer

The ultimate goal of most scientific studies is to understand the underlying causal mechanism between the involved variables. Structural causal models (SCMs) are widely used to represent such causal mechanisms. Given an SCM, causal queries…

Machine Learning · Statistics 2025-03-21 Beate Sick , Oliver Dürr

Neural networks are hypothesized to implement interpretable causal mechanisms, yet verifying this requires finding a causal abstraction -- a simpler, high-level Structural Causal Model (SCM) faithful to the network under interventions.…

Machine Learning · Computer Science 2026-03-02 Amir Asiaee

Causal discovery aims to extract qualitative causal knowledge in the form of causal graphs from data. Because causal ground truth is rarely known in the real world, simulated data plays a vital role in evaluating the performance of the…

Machine Learning · Computer Science 2025-12-17 Rebecca J. Herman , Jonas Wahl , Urmi Ninad , Jakob Runge

Without loss of generality, existing machine learning techniques may learn spurious correlation dependent on the domain, which exacerbates the generalization of models in out-of-distribution (OOD) scenarios. To address this issue, recent…

Machine Learning · Computer Science 2024-06-18 Bin Qin , Jiangmeng Li , Yi Li , Xuesong Wu , Yupeng Wang , Wenwen Qiang , Jianwen Cao
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