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Medical image segmentation is inherently uncertain. For a given image, there may be multiple plausible segmentation hypotheses, and physicians will often disagree on lesion and organ boundaries. To be suited to real-world application,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 João Lourenço Silva , Arlindo L. Oliveira

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Most medical image lesion segmentation methods rely on hand-crafted accurate annotations of the original image for supervised learning. Recently, a series of weakly supervised or unsupervised methods have been proposed to reduce the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-24 Jiawei Chen , Dingkang Yang , Yuxuan Lei , Lihua Zhang

In this paper, we develop a new weakly-supervised learning algorithm to learn to segment cancerous regions in histopathology images. Our work is under a multiple instance learning framework (MIL) with a new formulation, deep weak…

Computer Vision and Pattern Recognition · Computer Science 2017-08-30 Zhipeng Jia , Xingyi Huang , Eric I-Chao Chang , Yan Xu

Recent years have witnessed the great progress of deep neural networks on semantic segmentation, particularly in medical imaging. Nevertheless, training high-performing models require large amounts of pixel-level ground truth masks, which…

Computer Vision and Pattern Recognition · Computer Science 2020-04-10 Abdur R Feyjie , Reza Azad , Marco Pedersoli , Claude Kauffman , Ismail Ben Ayed , Jose Dolz

Multi-class cell segmentation in high-resolution Giga-pixel whole slide images (WSI) is critical for various clinical applications. Training such an AI model typically requires labor-intensive pixel-wise manual annotation from experienced…

Accurate identification of breast masses is crucial in diagnosing breast cancer; however, it can be challenging due to their small size and being camouflaged in surrounding normal glands. Worse still, it is also expensive in clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Xinyu Xiong , Churan Wang , Wenxue Li , Guanbin Li

Many successful methods developed for medical image analysis that are based on machine learning use supervised learning approaches, which often require large datasets annotated by experts to achieve high accuracy. However, medical data…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , David Cornell , Nils D. Forkert , Jacob L. Jaremko , Janet L. Ronsky

Two of the most common tasks in medical imaging are classification and segmentation. Either task requires labeled data annotated by experts, which is scarce and expensive to collect. Annotating data for segmentation is generally considered…

Computer Vision and Pattern Recognition · Computer Science 2020-12-01 Ozan Ciga , Anne L. Martel

In medical image diagnosis, pathology image analysis using semantic segmentation becomes important for efficient screening as a field of digital pathology. The spatial augmentation is ordinary used for semantic segmentation. Tumor images…

Machine Learning · Computer Science 2021-03-04 Takato Yasuno

Deep convolutional neural networks have shown outstanding performance in medical image segmentation tasks. The usual problem when training supervised deep learning methods is the lack of labeled data which is time-consuming and costly to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-04 Suman Sedai , Bhavna Antony , Ravneet Rai , Katie Jones , Hiroshi Ishikawa , Joel Schuman , Wollstein Gadi , Rahil Garnavi

Semantic segmentation is a challenging computer vision task demanding a significant amount of pixel-level annotated data. Producing such data is a time-consuming and costly process, especially for domains with a scarcity of experts, such as…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Sara Mousavi , Zhenning Yang , Kelley Cross , Dawnie Steadman , Audris Mockus

Image segmentation is a fundamental problem in biomedical image analysis. Recent advances in deep learning have achieved promising results on many biomedical image segmentation benchmarks. However, due to large variations in biomedical…

Computer Vision and Pattern Recognition · Computer Science 2017-06-16 Lin Yang , Yizhe Zhang , Jianxu Chen , Siyuan Zhang , Danny Z. Chen

Medical image segmentation typically necessitates a large and precisely annotated dataset. However, obtaining pixel-wise annotation is a labor-intensive task that requires significant effort from domain experts, making it challenging to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Heng Cai , Lei Qi , Qian Yu , Yinghuan Shi , Yang Gao

We have witnessed remarkable progress in foundation models in vision tasks. Currently, several recent works have utilized the segmenting anything model (SAM) to boost the segmentation performance in medical images, where most of them focus…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Haoran Wang , Lian Huai , Wenbin Li , Lei Qi , Xingqun Jiang , Yinghuan Shi

Sclera segmentation is crucial for developing automatic eye-related medical computer-aided diagnostic systems, as well as for personal identification and verification, because the sclera contains distinct personal features. Deep…

Computer Vision and Pattern Recognition · Computer Science 2025-01-15 Guanjun Wang , Lu Wang , Ning Niu , Qiaoyi Yao , Yixuan Wang , Sufen Ren , Shengchao Chen

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Deep learning-based medical image segmentation helps assist diagnosis and accelerate the treatment process while the model training usually requires large-scale dense annotation datasets. Weakly semi-supervised medical image segmentation is…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Shiman Li , Jiayue Zhao , Shaolei Liu , Xiaokun Dai , Chenxi Zhang , Zhijian Song

This work proves that semantic segmentation on minimally invasive surgical instruments can be improved by using training data that has been augmented through domain adaptation. The benefit of this method is twofold. Firstly, it suppresses…

Computer Vision and Pattern Recognition · Computer Science 2020-06-08 Iñigo Azqueta-Gavaldon , Florian Fröhlich , Klaus Strobl , Rudolph Triebel

Automatic medical image segmentation is a fundamental step in computer-aided diagnosis, yet fully supervised approaches demand extensive pixel-level annotations that are costly and time-consuming. To alleviate this burden, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Lei Shi , Gang Li , Junxing Zhang