Related papers: sJIVE: Supervised Joint and Individual Variation E…

Many real-world systems are described not only by data from a single source but via multiple data views. In genomic medicine, for instance, patients can be characterized by data from different molecular layers. Latent variable models with…

Reconstructing the structural connectivity between interacting units from observed activity is a challenge across many different disciplines. The fundamental first step is to establish whether or to what extent the interactions between the…

Modeling human behavioral data is challenging due to its scale, sparseness (few observations per individual), heterogeneity (differently behaving individuals), and class imbalance (few observations of the outcome of interest). An additional…

In biomedical science, a set of objects or persons can often be described by multiple distinct sets of features obtained from different data sources or modalities (called "multi-view data"). Classical machine learning methods ignore the…

Survival analysis is a cornerstone of clinical research by modeling time-to-event outcomes such as metastasis, disease relapse, or patient death. Unlike standard tabular data, survival data often come with incomplete event information due…

Joint species distribution models are popular in ecology for modeling covariate effects on species occurrence, while characterizing cross-species dependence. Data consist of multivariate binary indicators of the occurrences of different…

This tutorial demonstrates the estimation and interpretation of the Multilevel Social Relations Model for dyadic data. The Social Relations Model is appropriate for data structures in which individuals appear multiple times as both the…

We investigate the increasingly prominent task of jointly inferring multiple networks from nodal observations. While most joint inference methods assume that observations are available at all nodes, we consider the realistic and more…

Mixed outcome endpoints that combine multiple continuous and discrete components to form co-primary, multiple primary or composite endpoints are often employed as primary outcome measures in clinical trials. There are many advantages to…

In the era of big data, integrating multi-source functional data to extract a subspace that captures the shared subspace across sources has attracted considerable attention. In practice, data collection procedures often follow…

Embedding is a useful technique to project a high-dimensional feature into a low-dimensional space, and it has many successful applications including link prediction, node classification and natural language processing. Current approaches…

We have developed a strategy for the analysis of newly available binary data to improve outcome predictions based on existing data (binary or non-binary). Our strategy involves two modeling approaches for the newly available data, one…

In this paper, we develop a graphical modeling framework for the inference of networks across multiple sample groups and data types. In medical studies, this setting arises whenever a set of subjects, which may be heterogeneous due to…

Joint models for longitudinal biomarkers and time-to-event data are widely used in longitudinal studies. Many joint modeling approaches have been proposed to deal with different types of longitudinal biomarkers and survival outcomes.…

Multi-Entity Dependence Learning (MEDL) explores conditional correlations among multiple entities. The availability of rich contextual information requires a nimble learning scheme that tightly integrates with deep neural networks and has…

The optimization of the latents and parameters of diffusion models with respect to some differentiable metric defined on the output of the model is a challenging and complex problem. The sampling for diffusion models is done by solving…

The abundance of modern health data provides many opportunities for the use of machine learning techniques to build better statistical models to improve clinical decision making. Predicting time-to-event distributions, also known as…

Evidence-based decision making often relies on meta-analyzing multiple studies, which enables more precise estimation and investigation of generalizability. Integrative analysis of multiple heterogeneous studies is, however, highly…

Estimating an individual's potential response to continuously varied treatments is crucial for addressing causal questions across diverse domains, from healthcare to social sciences. However, existing methods are limited either to…

Federated or multi-site studies have distinct advantages over single-site studies, including increased generalizability, the ability to study underrepresented populations, and the opportunity to study rare exposures and outcomes. However,…