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Learning from heterogeneous data poses challenges such as combining data from various sources and of different types. Meanwhile, heterogeneous data are often associated with missingness in real-world applications due to heterogeneity and…

Machine Learning · Computer Science 2021-02-26 Yu Gong , Hossein Hajimirsadeghi , Jiawei He , Thibaut Durand , Greg Mori

Machine data is central to observability and diagnosis in modern computing systems, appearing in logs, metrics, telemetry traces, and configuration snapshots. When provided to large language models (LLMs), this data typically arrives as a…

Artificial Intelligence · Computer Science 2026-04-08 Jian Tan , Fan Bu , Yuqing Gao , Dev Khanolkar , Jason Mackay , Boris Sobolev , Lei Jin , Li Zhang

As data collection and simulation capabilities advance, multi-modal learning, the task of learning from multiple modalities and sources of data, is becoming an increasingly important area of research. Surrogate models that learn from data…

Machine Learning · Statistics 2026-05-13 Ian Taylor , Juliane Mueller , Julie Bessac

The need for interpretable models has fostered the development of self-explainable classifiers. Prior approaches are either based on multi-stage optimization schemes, impacting the predictive performance of the model, or produce…

Multimodal VAEs seek to model the joint distribution over heterogeneous data (e.g.\ vision, language), whilst also capturing a shared representation across such modalities. Prior work has typically combined information from the modalities…

Machine Learning · Computer Science 2022-12-19 Tom Joy , Yuge Shi , Philip H. S. Torr , Tom Rainforth , Sebastian M. Schmon , N. Siddharth

R\'enyi's information provides a theoretical foundation for tractable and data-efficient non-parametric density estimation, based on pair-wise evaluations in a reproducing kernel Hilbert space (RKHS). This paper extends this framework to…

Machine Learning · Computer Science 2022-03-09 Bo Hu , Shujian Yu , Jose C. Principe

In epidemiological and clinical studies, identifying patients' phenotypes based on longitudinal profiles is critical to understanding the disease's developmental patterns. The current study was motivated by data from a Canadian birth cohort…

Methodology · Statistics 2023-03-22 Zhiwen Tan , Chang Shen , Padmaja Subbarao , Wendy Lou , Zihang Lu

The clinical trial is a pivotal and costly process, often spanning multiple years and requiring substantial financial resources. Therefore, the development of clinical trial outcome prediction models aims to exclude drugs likely to fail and…

Machine Learning · Computer Science 2025-01-29 Wenhao Zheng , Liaoyaqi Wang , Dongshen Peng , Hongxia Xu , Yun Li , Hongtu Zhu , Tianfan Fu , Huaxiu Yao

Statistical analysis of large data sets offers new opportunities to better understand many processes. Yet, data accumulation often implies relaxing acquisition procedures or compounding diverse sources. As a consequence, such data sets…

Applications · Statistics 2018-05-01 François Husson , Julie Josse , Balasubramanian Narasimhan , Geneviève Robin

A master-worker architecture is presented for obtaining combined experimental results through joint fits of datasets from several experiments. The design of the architecture allows such joint fits to be performed keeping the data separated,…

Data Analysis, Statistics and Probability · Physics 2018-04-10 Eli Ben-Haim , René Brun , Bertrand Echenard , Thomas E. Latham

Consider a receiver in a multi-user network that wishes to decode several messages. Simultaneous joint typicality decoding is one of the most powerful techniques for determining the fundamental limits at which reliable decoding is possible.…

Information Theory · Computer Science 2019-01-11 Sung Hoon Lim , Chen Feng , Adriano Pastore , Bobak Nazer , Michael Gastpar

There is a growing need for flexible general frameworks that integrate individual-level data with external summary information for improved statistical inference. External information relevant for a risk prediction model may come in…

Methodology · Statistics 2023-04-11 Tian Gu , Jeremy M. G. Taylor , Bhramar Mukherjee

Missing data occur in many types of studies and typically complicate the analysis. Multiple imputation, either using joint modelling or the more flexible fully conditional specification approach, are popular and work well in standard…

Methodology · Statistics 2020-09-02 Nicole S. Erler , Dimitris Rizopoulos , Emmanuel M. E. H. Lesaffre

Causal discovery serves a pivotal role in mitigating model uncertainty through recovering the underlying causal mechanisms among variables. In many practical domains, such as healthcare, access to the data gathered by individual entities is…

Machine Learning · Computer Science 2024-02-13 Amin Abyaneh , Nino Scherrer , Patrick Schwab , Stefan Bauer , Bernhard Schölkopf , Arash Mehrjou

Machine learning (ML) research has yielded powerful tools for training accurate prediction models despite complex multivariate associations (e.g. interactions and heterogeneity). In fields such as medicine, improved interpretability of ML…

Machine Learning · Computer Science 2021-04-28 Robert Zhang , Rachael Stolzenberg-Solomon , Shannon M. Lynch , Ryan J. Urbanowicz

Modern deep learning methods have achieved impressive results across tasks from disease classification, estimating continuous biomarkers, to generating realistic medical images. Most of these approaches are trained to model conditional…

The standard methods for detecting differential gene expression are mostly designed for analyzing a single gene expression experiment. When data from multiple related gene expression studies are available, separately analyzing each study is…

Methodology · Statistics 2013-11-07 Yingying Wei , Hongkai Ji

Dynamic prediction of future clinical outcomes based on longitudinally measured predictors plays a crucial role in disease management and patient counseling, particularly when conventional static models are inadequate. Joint modeling of…

Methodology · Statistics 2025-07-30 Wenhao Li , Shikun Wang , Zhe Yin , Brad C. Astor , Wei Yang , Tom H. Greene , Liang Li

Motivated by recent findings that within-subject (WS) visit-to-visit variabilities of longitudinal biomarkers can be strong risk factors for health outcomes, this paper introduces and examines a new joint model of a longitudinal biomarker…

A conventional Bayesian approach to prediction uses the posterior distribution to integrate out parameters in a density for unobserved data conditional on the observed data and parameters. When the true posterior is intractable, it is…

Methodology · Statistics 2026-02-27 Lucas Kock , Scott A. Sisson , G. S. Rodrigues , David J. Nott
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