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Graph-level representations are crucial tools for characterising structural differences between graphs. However, comparing graphs with different cardinalities, even when sampled from the same underlying distribution, remains challenging.…

Machine Learning · Computer Science 2026-05-08 Katharina Limbeck , Nadja Häusermann , Martin Carrasco , Guy Wolf , Bastian Rieck

Graph self-supervised learning (GSSL) has demonstrated strong potential for generating expressive graph embeddings without the need for human annotations, making it particularly valuable in domains with high labeling costs such as molecular…

Machine Learning · Computer Science 2026-02-25 Jiele Wu , Haozhe Ma , Zhihan Guo , Thanh Vinh Vo , Tze Yun Leong

Accurate and scalable cancer diagnosis remains a critical challenge in modern pathology, particularly for malignancies such as breast, prostate, bone, and cervical, which exhibit complex histological variability. In this study, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Faisal Ahmed

Deep learning has recently gained popularity in digital pathology due to its high prediction quality. However, the medical domain requires explanation and insight for a better understanding beyond standard quantitative performance…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Miriam Hägele , Philipp Seegerer , Sebastian Lapuschkin , Michael Bockmayr , Wojciech Samek , Frederick Klauschen , Klaus-Robert Müller , Alexander Binder

Graph-based methods have been extensively applied to whole-slide histopathology image (WSI) analysis due to the advantage of modeling the spatial relationships among different entities. However, most of the existing methods focus on…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Tsai Hor Chan , Fernando Julio Cendra , Lan Ma , Guosheng Yin , Lequan Yu

-Background. Network neuroscience examines the brain as a complex system represented by a network (or connectome), providing deeper insights into the brain morphology and function, allowing the identification of atypical brain connectivity…

Neurons and Cognition · Quantitative Biology 2020-09-01 Mert Lostar , Islem Rekik

We propose UTS, a unit-based tissue segmentation framework for histopathology that classifies each fixed-size 32 * 32 tile, rather than each pixel, as the segmentation unit. This approach reduces annotation effort and improves computational…

Image and Video Processing · Electrical Eng. & Systems 2025-11-05 Ashkan Shakarami , Azade Farshad , Yousef Yeganeh , Lorenzo Nicole , Peter Schüffler , Stefano Ghidoni , Nassir Navab

As data structures and mathematical objects used for complex systems modeling, hypergraphs sit nicely poised between on the one hand the world of network models, and on the other that of higher-order mathematical abstractions from algebra,…

Objective: Modern medicine needs to shift from a wait and react, curative discipline to a preventative, interdisciplinary science aiming at providing personalised, systemic and precise treatment plans to patients. The aim of this work is to…

Machine Learning · Statistics 2020-09-18 Pietro Barbiero , Ramon Viñas Torné , Pietro Lió

This study explores the use of graph neural networks (GNNs) with hierarchical pooling and multiple convolution layers for cancer classification based on RNA-seq data. We combine gene expression data from The Cancer Genome Atlas (TCGA) with…

Machine Learning · Computer Science 2026-01-13 Thomas Vaitses Fontanari , Mariana Recamonde-Mendoza

Human epidermal growth factor receptor 2 (HER2) is an important prognostic and predictive factor which is overexpressed in 15-20% of breast cancer (BCa). The determination of its status is a key clinical decision making step for selection…

Computer Vision and Pattern Recognition · Computer Science 2021-10-13 Wenqi Lu , Michael Toss , Emad Rakha , Nasir Rajpoot , Fayyaz Minhas

Discovering human cognitive and emotional states using multi-modal physiological signals draws attention across various research applications. Physiological responses of the human body are influenced by human cognition and commonly used to…

Histopathologists establish cancer grade by assessing histological structures, such as glands in prostate cancer. Yet, digital pathology pipelines often rely on grid-based tiling that ignores tissue architecture. This introduces irrelevant…

The surge in wireless connectivity demand, coupled with the finite nature of spectrum resources, compels the development of efficient spectrum management approaches. Spectrum sharing presents a promising avenue, although it demands precise…

Machine Learning · Computer Science 2026-03-11 Mohamad Alkadamani , Halim Yanikomeroglu , Amir Ghasemi

Breast cancer is one of the most common cancers among women globally, with early diagnosis and precise classification being crucial. With the advancement of deep learning and computer vision, the automatic classification of breast tissue…

Image and Video Processing · Electrical Eng. & Systems 2025-01-20 Jiacheng Hao , Yiqing Liu , Siqi Zeng , Yonghong He

We propose a novel method for hierarchical entity classification that embraces ontological structure at both training and during prediction. At training, our novel multi-level learning-to-rank loss compares positive types against negative…

Computation and Language · Computer Science 2020-04-07 Tongfei Chen , Yunmo Chen , Benjamin Van Durme

Numerous deep learning-based solutions have been proposed for histopathological image analysis over the past years. While they usually demonstrate exceptionally high accuracy, one key question is whether their precision might be affected by…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Andrey Ignatov , Grigory Malivenko

Deep neural networks have introduced significant advancements in the field of machine learning-based analysis of digital pathology images including prostate tissue images. With the help of transfer learning, classification and segmentation…

The Intensive Care Unit (ICU) is one of the most important parts of a hospital, which admits critically ill patients and provides continuous monitoring and treatment. Various patient outcome prediction methods have been attempted to assist…

Machine Learning · Computer Science 2023-10-24 Yuxi Liu , Zhenhao Zhang , Shaowen Qin , Flora D. Salim , Antonio Jimeno Yepes , Jun Shen , Jiang Bian

Most recently, the pathology diagnosis of cancer is shifting to integrating molecular makers with histology features. It is a urgent need for digital pathology methods to effectively integrate molecular markers with histology, which could…

Image and Video Processing · Electrical Eng. & Systems 2023-06-28 Xiaofei Wang , Stephen Price , Chao Li
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