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We develop a variational Bayesian (VB) approach for estimating large-scale dynamic network models in the network autoregression framework. The VB approach allows for the automatic identification of the dynamic structure of such a model and…

Methodology · Statistics 2021-02-19 Wei-Ting Lai , Ray-Bing Chen , Ying Chen , Thorsten Koch

We propose a hemodynamic reduced-order model bridging macroscopic and meso-scopic blood flow circulation scales from arteries to capillaries. In silico tree like vascular geometries, mathematically described by graphs, are synthetically…

Medical Physics · Physics 2019-07-29 Olivier Adjoua , Stéphanie Pitre-Champagnat , Didier Lucor

Globally, cardiovascular diseases (CVDs) are the leading cause of mortality, accounting for an estimated 17.9 million deaths annually. One critical clinical objective is the early detection of CVDs using electrocardiogram (ECG) data, an…

Signal Processing · Electrical Eng. & Systems 2024-01-25 Siyang Wu

An important application of haptic technology to digital product development is in virtual prototyping (VP), part of which deals with interactive planning, simulation, and verification of assembly-related activities, collectively called…

Human-Computer Interaction · Computer Science 2017-12-12 Morad Behandish , Horea T. Ilies

Computer modeling of the cardiovascular system has potential to revolutionize personalized medical care. This is especially promising for congenital heart defects, such as ventricular septal defect (VSD), a hole between the two ventricles…

Tissues and Organs · Quantitative Biology 2026-02-05 Mitchel J. Colebank , Alfonso Limon , Anthony Chang , Brandon Wong , Wyman Lai , Hamilton Baker

We investigate the performance and characteristics of currently available VB and MCMC software to explore the practicability of available approaches and provide guidance for clinical practitioners. Two case studies are used to fully explore…

Applications · Statistics 2024-08-29 Brian Buckley , Adrian O'Hagan , Marie Galligan

Determining brain hemodynamics plays a critical role in the diagnosis and treatment of various cerebrovascular diseases. In this work, we put forth a physics-informed deep learning framework that augments sparse clinical measurements with…

Medical Physics · Physics 2021-08-27 Mohammad Sarabian , Hessam Babaee , Kaveh Laksari

Coronary artery disease, caused by the narrowing of coronary vessels due to atherosclerosis, is the leading cause of death worldwide. The diagnostic gold standard, fractional flow reserve (FFR), measures the trans-stenotic pressure ratio…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Guido Nannini , Julian Suk , Patryk Rygiel , Simone Saitta , Luca Mariani , Riccardo Maragna , Andrea Baggiano , Gianluca Pontone , Jelmer M. Wolterink , Alberto Redaelli

Cardiovascular diseases and heart failures in particular are the main cause of non-communicable disease mortality in the world. Constant patient monitoring enables better medical treatment as it allows practitioners to react on time and…

Artificial Intelligence · Computer Science 2021-04-21 Kordian Gontarska , Weronika Wrazen , Jossekin Beilharz , Robert Schmid , Lauritz Thamsen , Andreas Polze

Cardiovascular diseases (CVDs) are any serious illness of the heart, which require accurate diagnosis to prevent fatal consequences. Hyperparameter tuning plays a critical role in optimizing machine learning model performance by selecting…

Machine Learning · Computer Science 2026-05-19 Abhay Kumar Pathak , Mrityunjay Chaubey , Manjari Gupta

Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation, a type of valvular heart disease. Metrics derived from blood flows are used to indicate aortic regurgitation onset and evaluate its…

Computer Vision and Pattern Recognition · Computer Science 2022-04-07 Derek Long , Cameron McMurdo , Edward Ferdian , Charlene A. Mauger , David Marlevi , Alistair A. Young , Martyn P. Nash

Analysing the haemodynamics of flow in carotid artery disease serves as a means to better understand the development and progression of associated complex diseases. Carotid artery disease can predispose people to major adverse…

With a surge in online medical advising remote monitoring of patient vitals is required. This can be facilitated with the Remote Photoplethysmography (rPPG) techniques that compute vital signs from facial videos. It involves processing…

Artificial Intelligence · Computer Science 2022-08-23 Amtul Haq Ayesha , Donghao Qiao , Farhana Zulkernine

Recent advancements in Artificial Intelligence (AI) have significantly influenced the field of Cardiovascular Disease (CVD) analysis, particularly in image-based diagnostics. Our paper presents an extensive review of AI applications in…

Image and Video Processing · Electrical Eng. & Systems 2025-12-12 Xin Wang , Mingcheng Hu , Connie W. Tsao , Hongtu Zhu

The CVS is composed of numerous interacting and dynamically regulated physiological subsystems which each generate measurable periodic components such that the CVS can itself be presented as a system of weakly coupled oscillators. The…

We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular.…

Fluid Dynamics · Physics 2008-11-11 Renat A. Sultanov , Dennis Guster

The accurate quantification of left ventricular (LV) deformation/strain shows significant promise for quantitatively assessing cardiac function for use in diagnosis and therapy planning (Jasaityte et al., 2013). However, accurate estimation…

We address the problem of modeling constrained hospital resources in the midst of the COVID-19 pandemic in order to inform decision-makers of future demand and assess the societal value of possible interventions. For broad applicability, we…

Leveraging big data for patient care is promising in many medical fields such as cardiovascular health. For example, hemodynamic biomarkers like wall shear stress could be assessed from patient-specific medical images via machine learning…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Julian Suk , Jolanda J. Wentzel , Patryk Rygiel , Joost Daemen , Daniel Rueckert , Jelmer M. Wolterink

Numerical simulations to evaluate thoracic aortic hemodynamics include a computational fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD neglects the arterial deformation along the cardiac cycle by…

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