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This review paper explores recent advances in deep learning approaches for non-invasive cognitive impairment detection. We examine various non-invasive indicators of cognitive decline, including speech and language, facial, and motoric…

Machine Learning · Computer Science 2025-04-16 Muath Alsuhaibani , Ali Pourramezan Fard , Jian Sun , Farida Far Poor , Peter S. Pressman , Mohammad H. Mahoor

Automatic assessment of cognitive impairment from spontaneous speech offers a promising, non-invasive avenue for early cognitive screening. However, current approaches often lack generalizability when deployed across different languages and…

Artificial Intelligence · Computer Science 2025-10-20 Rui Feng , Zhiyao Luo , Wei Wang , Yuting Song , Yong Liu , Tingting Zhu , Jianqing Li , Xingyao Wang

Alzheimer's dementia (AD) is of increasing concern as populations achieve longer lifespans. Many of the recent failed AD clinical trials recruiting cognitively intact individuals had a low number of AD events and were thus underpowered.…

Methodology · Statistics 2025-03-21 Julia Gallini , Zach Baucom , Yorghos Tripodis

A personalized LLM should remember user facts, apply them correctly, and adapt over time to provide responses that the user prefers. Existing LLM personalization benchmarks are largely centered on two axes: accurately recalling user…

Machine Learning · Computer Science 2025-12-16 Md Awsafur Rahman , Adam Gabrys , Doug Kang , Jingjing Sun , Tian Tan , Ashwin Chandramouli

Speech pauses, alongside content and structure, offer a valuable and non-invasive biomarker for detecting dementia. This work investigates the use of pause-enriched transcripts in transformer-based language models to differentiate the…

Audio and Speech Processing · Electrical Eng. & Systems 2024-08-28 Franziska Braun , Sebastian P. Bayerl , Florian Hönig , Hartmut Lehfeld , Thomas Hillemacher , Tobias Bocklet , Korbinian Riedhammer

Mobile manipulators in the home can enable people with cervical spinal cord injury (cSCI) to perform daily physical household tasks that they could not otherwise do themselves. However, paralysis in these users often limits access to…

Robotics · Computer Science 2026-02-04 Jehan Yang , Eleanor Hodgson , Cindy Sun , Zackory Erickson , Doug Weber

Although pain is frequent in old age, older adults are often undertreated for pain. This is especially the case for long-term care residents with moderate to severe dementia who cannot report their pain because of cognitive impairments that…

Computer Vision and Pattern Recognition · Computer Science 2021-01-12 Siavash Rezaei , Abhishek Moturu , Shun Zhao , Kenneth M. Prkachin , Thomas Hadjistavropoulos , Babak Taati

This study investigates the utility of speech signals for AI-based depression screening across varied interaction scenarios, including psychiatric interviews, chatbot conversations, and text readings. Participants include depressed patients…

Sound · Computer Science 2024-06-13 Yangbin Chen , Chenyang Xu , Chunfeng Liang , Yanbao Tao , Chuan Shi

In this paper, we propose a dual aggregation network to adaptively aggregate different information in infant brain MRI segmentation. More precisely, we added two modules based on 3D-UNet to better model information at different levels and…

Computer Vision and Pattern Recognition · Computer Science 2020-03-31 Zhihao Lei , Lin Qi , Ying Wei , Yunlong Zhou

Early detection of anxiety is crucial for reducing the suffering of individuals with mental disorders and improving treatment outcomes. Utilizing an mHealth platform for anxiety screening can be particularly practical in improving screening…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Haimiao Mo , Yuchen Li , Shanlin Yang , Wei Zhang , Shuai Ding

Quality patient-provider communication is critical to improve clinical care and patient outcomes. While progress has been made with communication skills training for clinicians, significant gaps exist in how to best monitor, measure, and…

Human-Computer Interaction · Computer Science 2024-07-12 Zhiyuan Wang , Nusayer Hassan , Virginia LeBaron , Tabor E. Flickinger , David Ling , James Edwards , Congyu Wu , Mehdi Boukhechba , Laura E. Barnes

N-of-1 trials are multi-crossover self-experiments that allow individuals to systematically evaluate the effect of interventions on their personal health goals. Although several tools for N-of-1 trials exist, none support non-experts in…

Human-Computer Interaction · Computer Science 2021-08-03 Alexander M. Zenner , Erwin Böttinger , Stefan Konigorski

Neurocognitive disorders (NCDs), such as Alzheimer's disease, are globally prevalent and require scalable screening methods for proactive management. Prior research has explored the potential of technologies like conversational AI (CAI) to…

Human-Computer Interaction · Computer Science 2026-04-23 Jiaxiong Hu , Ruowen Niu , Qiuxin Du , Chenzhuo Xiang , Yirui Zuo , Jihong Jeung , Xiaojuan Ma

Cognitive impairment detection through spontaneous speech is a promising avenue for early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI), where timely intervention can significantly improve patient outcomes. The…

Sound · Computer Science 2025-02-19 Yifan Gao , Long Guo , Hong Liu

Wearable AI is often designed as always-available, yet continuous availability can conflict with how people work and socialize, creating discomfort around privacy, disruption, and unclear system boundaries. This paper explores episodic use…

Human-Computer Interaction · Computer Science 2026-03-10 Yonatan Tussa , Andy Heredia

Large language models (LLMs) are increasingly integrated into users' daily lives, leading to a growing demand for personalized outputs. Previous work focuses on leveraging a user's own history, overlooking inter-user differences that are…

Computation and Language · Computer Science 2025-09-23 Yilun Qiu , Tianhao Shi , Xiaoyan Zhao , Fengbin Zhu , Yang Zhang , Fuli Feng

Differential diagnosis of dementia is challenging due to overlapping symptoms, with structural magnetic resonance imaging (MRI) being the primary method for diagnosis. Despite the clinical value of computer-aided differential diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Yitong Li , Tom Nuno Wolf , Sebastian Pölsterl , Igor Yakushev , Dennis M. Hedderich , Christian Wachinger

Interpreting machine learning model decisions is crucial for high-risk applications like healthcare. In digital pathology, large whole slide images (WSIs) are decomposed into smaller tiles and tile-derived features are processed by…

Image and Video Processing · Electrical Eng. & Systems 2024-07-03 Tomé Albuquerque , Anil Yüce , Markus D. Herrmann , Alvaro Gomariz

Major Depressive Disorder and anxiety disorders affect millions globally, contributing significantly to the burden of mental health issues. Early screening is crucial for effective intervention, as timely identification of mental health…

Dementia is under-recognized in the community, under-diagnosed by healthcare professionals, and under-coded in claims data. Information on cognitive dysfunction, however, is often found in unstructured clinician notes within medical records…