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Quantitative susceptibility mapping (QSM) has been increasingly applied in longitudinal studies of neurodegenerative diseases and aging to assess temporal alterations in brain iron and myelin. The accuracy of such investigations depends on…

Quantitative Methods · Quantitative Biology 2026-05-05 Jiye Kim , Hwihun Jeong , Taechang Kim , Eunseon Jeong , Jinhee Jang , Yangsean Choi , Jongho Lee

Early prognosis of Alzheimer's dementia is hard. Mild cognitive impairment (MCI) typically precedes Alzheimer's dementia, yet only a fraction of MCI individuals will progress to dementia, even when screened using biomarkers. We propose here…

Quantitative Methods · Quantitative Biology 2018-03-05 Christian Dansereau , Angela Tam , AmanPreet Badhwar , Sebastian Urchs , Pierre Orban , Pedro Rosa-Neto , Pierre Bellec

This paper presents our submission to the PROCESS Challenge 2025, focusing on spontaneous speech analysis for early dementia detection. For the three-class classification task (Healthy Control, Mild Cognitive Impairment, and Dementia), we…

Audio and Speech Processing · Electrical Eng. & Systems 2025-05-28 Yin-Long Liu , Yuanchao Li , Rui Feng , Liu He , Jia-Xin Chen , Yi-Ming Wang , Yu-Ang Chen , Yan-Han Peng , Jia-Hong Yuan , Zhen-Hua Ling

Alzheimer's Dementia (AD) is an incurable, debilitating, and progressive neurodegenerative condition that affects cognitive function. Early diagnosis is important as therapeutics can delay progression and give those diagnosed vital time.…

Machine Learning · Computer Science 2023-02-28 Thomas Searle , Zina Ibrahim , Richard Dobson

Machine learning (ML) is being applied to a diverse and ever-growing set of domains. In many cases, domain experts - who often have no expertise in ML or data science - are asked to use ML predictions to make high-stakes decisions. Multiple…

Human-Computer Interaction · Computer Science 2021-09-21 Alexandra Zytek , Dongyu Liu , Rhema Vaithianathan , Kalyan Veeramachaneni

Multimodal interactive maps are a solution for presenting spatial information to visually impaired people. In this paper, we present an interactive multimodal map prototype that is based on a tactile paper map, a multi-touch screen and…

Human-Computer Interaction · Computer Science 2012-07-20 Anke Brock , Philippe Truillet , Bernard Oriola , Delphine Picard , Christophe Jouffrais

Machine learning techniques combined with in-home monitoring technologies provide a unique opportunity to automate diagnosis and early detection of adverse health conditions in long-term conditions such as dementia. However, accessing…

Early detection is crucial for timely intervention aimed at preventing and slowing the progression of neurocognitive disorder (NCD), a common and significant health problem among the aging population. Recent evidence has suggested that…

Computation and Language · Computer Science 2025-06-11 Yuejiao Wang , Xianmin Gong , Xixin Wu , Patrick Wong , Hoi-lam Helene Fung , Man Wai Mak , Helen Meng

Dementia is a progressive neurological disorder that profoundly affects the daily lives of older adults, impairing abilities such as verbal communication and cognitive function. Early diagnosis is essential for enhancing both lifespan and…

Computational Engineering, Finance, and Science · Computer Science 2023-11-07 Kaiying Lin , Peter Washington

Patient simulators are gaining traction in mental health training by providing scalable exposure to complex and sensitive patient interactions. Simulating depressed patients is particularly challenging, as safety constraints and high…

Computation and Language · Computer Science 2026-04-29 Nguyen Khoi Hoang , Shuhaib Mehri , Tse-An Hsu , Yi-Jyun Sun , Quynh Xuan Nguyen Truong , Khoa D Doan , Dilek Hakkani-Tür

INTRODUCTION: Mild cognitive impairment (MCI) is characterized by a decline in cognitive functions beyond typical age and education-related expectations. Since, MCI has been linked to reduced social interactions and increased aimless…

Artificial Intelligence · Computer Science 2024-08-21 Chaitra Hegde , Yashar Kiarashi , Allan I Levey , Amy D Rodriguez , Hyeokhyen Kwon , Gari D Clifford

New tactile interfaces such as swell form printing or refreshable tactile displays promise to allow visually impaired people to analyze data. However, it is possible that design guidelines and familiar encodings derived from experiments on…

Human-Computer Interaction · Computer Science 2024-10-14 Areen Khalaila , Lane Harrison , Nam Wook Kim , Dylan Cashman

Recently, there has been a growing interest in developing AI-enabled chatbot-based symptom checker (CSC) apps in the healthcare market. CSC apps provide potential diagnoses for users and assist them with self-triaging based on Artificial…

Human-Computer Interaction · Computer Science 2021-01-14 Yue You , Xinning Gui

Interaction is a fundamental part of using any computer system but it is still an issue for people with special needs. In order to improve this situation, this paper describes a new device-interaction model based on adaptation rules for…

Human-Computer Interaction · Computer Science 2023-01-03 Juan Jesus Ojeda-Castelo , Jose A. Piedra-Fernandez , Luis Iribarne

Assessing the accessibility of unfamiliar built environments is critical for people with disabilities. However, manual assessments, performed by users or their personal health professionals, are laborious and unscalable, while automatic…

Human-Computer Interaction · Computer Science 2026-01-23 William Huang , Xia Su , Jon E. Froehlich , Yang Zhang

This research paper addresses the limitations of current mobile accessibility services like TalkBack, which provide manual gesture-based sequential feedback to BVI users. Motivated by the promise of large language models (LLMs), this paper…

Human-Computer Interaction · Computer Science 2026-05-12 Joshua Owusu Ansah , Anuj Kapoor , Ayush Khanna , Manvika Vinod , Precious Njeck , Shuai Gao

Background. Personality is a primary object of interest in clinical psychology and psychiatry. It is most often measured using questionnaires, which rely on Factor Analysis (FA) to identify essential domains corresponding to highly…

Human-Computer Interaction · Computer Science 2024-03-15 Marcantonio Gagliardi , Marina Bonadeni , Sara Billai , Gian Luca Marcialis

Individuals with fine motor impairments, such as those caused by conditions like Parkinson's disease, cerebral palsy, or dyspraxia, face significant challenges in interacting with traditional computer interfaces. Historically, scripted…

Human-Computer Interaction · Computer Science 2024-11-20 Shridhar Mehendale , Ankit Walishetti

Learning difficulties pose significant challenges for students, impacting their academic performance and overall educational experience. These difficulties could sometimes put students into a downward spiral that lack of educational…

Human-Computer Interaction · Computer Science 2024-03-12 Aaron Hu

LLMs are popular among clinicians for decision-support because of simple text-based interaction. However, their impact on clinicians' performance is ambiguous. Not knowing how clinicians use this new technology and how they compare it to…

Human-Computer Interaction · Computer Science 2026-02-02 Behnam Rahdari , Sameer Shaikh , Jonathan H Chen , Tobias Gerstenberg , Shriti Raj