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In the past decade, deep learning (DL) has achieved unprecedented success in numerous fields including computer vision, natural language processing, and healthcare. In particular, DL is experiencing an increasing development in applications…

Computer Vision and Pattern Recognition · Computer Science 2020-07-15 Liang Zhang , Johann Li , Ping Li , Xiaoyuan Lu , Peiyi Shen , Guangming Zhu , Syed Afaq Shah , Mohammed Bennarmoun , Kun Qian , Björn W. Schuller

Peptide therapeutics are widely regarded as the "third generation" of drugs, yet progress in peptide Machine Learning (ML) are hindered by the absence of standardized benchmarks. Here we present PepBenchmark, which unifies datasets,…

Machine Learning · Computer Science 2026-04-14 Jiahui Zhang , Rouyi Wang , Kuangqi Zhou , Tianshu Xiao , Lingyan Zhu , Yaosen Min , Yang Wang

Deep learning's rise since the early 2010s has transformed fields like computer vision and natural language processing and strongly influenced biomedical research. For drug discovery specifically, a key inflection - akin to vision's…

Machine Learning · Computer Science 2025-11-19 Antonia Ebner , Christoph Bartmann , Sonja Topf , Sohvi Luukkonen , Johannes Schimunek , Günter Klambauer

Machine learning (ML) approaches have demonstrated promising results in a wide range of healthcare applications. Data plays a crucial role in developing ML-based healthcare systems that directly affect people's lives. Many of the ethical…

Cognitive diagnosis has been developed for decades as an effective measurement tool to evaluate human cognitive status such as ability level and knowledge mastery. It has been applied to a wide range of fields including education, sport,…

Artificial Intelligence · Computer Science 2024-07-09 Fei Wang , Weibo Gao , Qi Liu , Jiatong Li , Guanhao Zhao , Zheng Zhang , Zhenya Huang , Mengxiao Zhu , Shijin Wang , Wei Tong , Enhong Chen

In modern dynamic constantly developing society, more and more people suffer from chronic and serious diseases and doctors and patients need special and sophisticated medical and health support. Accordingly, prominent health stakeholders…

Computers and Society · Computer Science 2022-08-10 Mirjana Ivanovic , Serge Autexier , Miltiadis Kokkonidis

Clinical and biomedical research in low-resource settings often faces significant challenges due to the need for high-quality data with sufficient sample sizes to construct effective models. These constraints hinder robust model training…

Novel digital data sources and tools like machine learning (ML) and artificial intelligence (AI) have the potential to revolutionize data about development and can contribute to monitoring and mitigating humanitarian problems. The potential…

Digital Twin (DT) technology has emerged as a transformative approach in healthcare, but its application in personalized patient care remains limited. This paper aims to present a practical implementation of DT in the management of chronic…

Quantitative Methods · Quantitative Biology 2025-07-17 Javad M Alizadeh , Mukesh K Patel , Huanmei Wu

The emergence and rapid development of the Internet of Medical Things (IoMT), an application of the Internet of Things into the medical and healthcare systems, have brought many changes and challenges to modern medical and healthcare…

Cryptography and Security · Computer Science 2019-02-11 Zhitao Guan , Zefang Lv , Xiaojiang Du , Longfei Wu , Mohsen Guizani

Background and Objectives: Reproducibility is a major challenge in developing machine learning (ML)-based solutions in computational pathology (CompPath). The NCI Imaging Data Commons (IDC) provides >120 cancer image collections according…

The astounding success made by artificial intelligence (AI) in healthcare and other fields proves that AI can achieve human-like performance. However, success always comes with challenges. Deep learning algorithms are data-dependent and…

Image and Video Processing · Electrical Eng. & Systems 2021-06-25 Johann Li , Guangming Zhu , Cong Hua , Mingtao Feng , BasheerBennamoun , Ping Li , Xiaoyuan Lu , Juan Song , Peiyi Shen , Xu Xu , Lin Mei , Liang Zhang , Syed Afaq Ali Shah , Mohammed Bennamoun

Drug addiction is a complex and pervasive global challenge that continues to pose significant public health concerns. Traditional approaches to anti-addiction drug discovery have struggled to deliver effective therapeutics, facing high…

Biomolecules · Quantitative Biology 2025-02-11 Dong Chen , Jian Jiang , Zhe Su , Guo-Wei Wei

As the amount of scientific data continues to grow at ever faster rates, the research community is increasingly in need of flexible computational infrastructure that can support the entirety of the data science lifecycle, including…

Computers and Society · Computer Science 2016-04-12 Robert L. Grossman , Allison Heath , Mark Murphy , Maria Patterson , Walt Wells

This study explores the application and performance of Transformational Machine Learning (TML) in drug discovery. TML, a meta learning algorithm, excels in exploiting common attributes across various domains, thus developing composite…

Biomolecules · Quantitative Biology 2023-10-02 Adnan Mahmud , Oghenejokpeme Orhobor , Ross D. King

Accurate and robust drug response prediction is of utmost importance in precision medicine. Although many models have been developed to utilize the representations of drugs and cancer cell lines for predicting cancer drug responses (CDR),…

Quantitative Methods · Quantitative Biology 2023-11-22 Xiaoqiong Xia , Chaoyu Zhu , Yuqi Shan , Fan Zhong , Lei Liu

Recent advancements in Earth system science have been marked by the exponential increase in the availability of diverse, multivariate datasets characterised by moderate to high spatio-temporal resolutions. Earth System Data Cubes (ESDCs)…

While the field of medical image analysis has undergone a transformative shift with the integration of machine learning techniques, the main challenge of these techniques is often the scarcity of large, diverse, and well-annotated datasets.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Stefano Woerner , Arthur Jaques , Christian F. Baumgartner

Biomedical research centers can empower basic discovery and novel therapeutic strategies by leveraging their large-scale datasets from experiments and patients. This data, together with new technologies to create and analyze it, has ushered…

With recent advancements in AI and computation tools, intelligent paradigms emerged to empower different fields such as healthcare robots with new capabilities. Advanced AI robotic algorithms (e.g., reinforcement learning) can be trained…

Robotics · Computer Science 2024-07-25 Reza Abiri , Ali Rabiee , Sima Ghafoori , Anna Cetera
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