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In today's world of advanced AI technologies, data management is a critical component of any AI/ML solution. Effective data management is vital for the creation and maintenance of high-quality, diverse datasets, which significantly enhance…

Machine Learning · Computer Science 2024-09-20 Sai Vishwanath Venkatesh , Atra Akandeh , Madhu Lokanath

Progress in Type 1 Diabetes (T1D) algorithm development is limited by the fragmentation and lack of standardization across existing T1D management datasets. Current datasets differ substantially in structure and are time-consuming to access…

Machine Learning · Computer Science 2026-04-23 Miriam K. Wolff , Peter Calhoun , Eleonora Maria Aiello , Yao Qin , Sam F. Royston

Major depressive disorder (MDD) is a heterogeneous condition; multiple underlying neurobiological substrates could be associated with treatment response variability. Understanding the sources of this variability and predicting outcomes has…

Traditional drug discovery is a long, expensive, and complex process. Advances in Artificial Intelligence (AI) and Machine Learning (ML) are beginning to change this narrative. Here, we provide a comprehensive overview of different AI and…

Artificial Intelligence · Computer Science 2024-11-12 Khartik Uppalapati , Eeshan Dandamudi , S. Nick Ice , Gaurav Chandra , Kirsten Bischof , Christian L. Lorson , Kamal Singh

Natural medicines, particularly Traditional Chinese Medicine (TCM), are gaining global recognition for their therapeutic potential in addressing human symptoms and diseases. TCM, with its systematic theories and extensive practical…

Computation and Language · Computer Science 2025-05-20 Zhi Liu , Tao Yang , Jing Wang , Yexin Chen , Zhan Gao , Jiaxi Yang , Kui Chen , Bingji Lu , Xiaochen Li , Changyong Luo , Yan Li , Xiaohong Gu , Peng Cao

For the past decades medical robotic solutions were mostly based on the concept of tele-manipulation. While their design was extremely intelligent, allowing for better access, improved dexterity, reduced tremor, and improved imaging, their…

Robotics · Computer Science 2026-04-14 Nassir Navab , Zhongliang Jiang

The rise of large language models (LLMs) has transformed healthcare by offering clinical guidance, yet their direct deployment to patients poses safety risks due to limited domain expertise. To mitigate this, we propose repositioning LLMs…

Computation and Language · Computer Science 2025-10-14 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Prayag Tiwari , Xiang Wan , Feng Jiang , Benyou Wang

The role of data in building AI systems has recently been significantly magnified by the emerging concept of data-centric AI (DCAI), which advocates a fundamental shift from model advancements to ensuring data quality and reliability.…

Artificial Intelligence · Computer Science 2023-04-04 Daochen Zha , Zaid Pervaiz Bhat , Kwei-Herng Lai , Fan Yang , Xia Hu

A comprehensive pharmaceutical recommendation system was designed based on the patients and drugs features extracted from Drugs.com and Druglib.com. First, data from these databases were combined, and a dataset of patients and drug…

Pharmaceutical industry can better leverage its data assets to virtualize drug discovery through a collaborative machine learning platform. On the other hand, there are non-negligible risks stemming from the unintended leakage of…

Cryptography and Security · Computer Science 2022-06-10 Balazs Pejo , Mina Remeli , Adam Arany , Mathieu Galtier , Gergely Acs

Drug discovery remains a slow and expensive process that involves many steps, from detecting the target structure to obtaining approval from the Food and Drug Administration (FDA), and is often riddled with safety concerns. Accurate…

Quantitative Methods · Quantitative Biology 2025-08-22 Ali Vefghi , Zahed Rahmati , Mohammad Akbari

Developing new drugs for target diseases is a time-consuming and expensive task, drug repurposing has become a popular topic in the drug development field. As much health claim data become available, many studies have been conducted on the…

Machine Learning · Computer Science 2023-02-22 Yaobin Ling , Pulakesh Upadhyaya , Luyao Chen , Xiaoqian Jiang , Yejin Kim

Drug recommendation (DR) systems aim to support healthcare professionals in selecting appropriate medications based on patients' medical conditions. State-of-the-art approaches utilize deep learning techniques for improving DR, but fall…

Information Retrieval · Computer Science 2025-11-03 Yu Lin , Zhen Jia , Philipp Christmann , Xu Zhang , Shengdong Du , Tianrui Li

With the advent of Digital Therapeutics (DTx), the development of software as a medical device (SaMD) for mobile and wearable devices has gained significant attention in recent years. Existing DTx evaluations, such as randomized clinical…

Human-Computer Interaction · Computer Science 2022-09-20 Uichin Lee , Gyuwon Jung , Eun-Yeol Ma , Jin San Kim , Heepyung Kim , Jumabek Alikhanov , Youngtae Noh , Heeyoung Kim

Artificial Intelligence (AI) has made its way into various scientific fields, providing astonishing improvements over existing algorithms for a wide variety of tasks. In recent years, there have been severe concerns over the trustworthiness…

Machine Learning · Computer Science 2024-08-20 Surbhi Mittal , Kartik Thakral , Richa Singh , Mayank Vatsa , Tamar Glaser , Cristian Canton Ferrer , Tal Hassner

The recently unprecedented advancements in Large Language Models (LLMs) have propelled the medical community by establishing advanced medical-domain models. However, due to the limited collection of medical datasets, there are only a few…

Computation and Language · Computer Science 2024-06-10 Ping Yu , Kaitao Song , Fengchen He , Ming Chen , Jianfeng Lu

Data science models, although successful in a number of commercial domains, have had limited applicability in scientific problems involving complex physical phenomena. Theory-guided data science (TGDS) is an emerging paradigm that aims to…

A main challenge of data-driven sciences is how to make maximal use of the progressively expanding databases of experimental datasets in order to keep research cumulative. We introduce the idea of a modeling-based dataset retrieval engine…

Quantitative Methods · Quantitative Biology 2015-06-19 Ali Faisal , Jaakko Peltonen , Elisabeth Georgii , Johan Rung , Samuel Kaski

Despite the excitement behind biomedical artificial intelligence (AI), access to high-quality, diverse, and large-scale data - the foundation for modern AI systems - is still a bottleneck to unlocking its full potential. To address this…

Despite the growing scale of medical Vision-Language datasets, the impact of dataset quality on model performance remains under-explored. We introduce Open-PMC, a high-quality medical dataset from PubMed Central, containing 2.2 million…