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This brief article accompanies a fluid dynamics video presenting the results of a large-eddy simulation of the flow in a realistic left heart. The left heart geometry, from the pulmonary veins to the aortic root, is extracted from medical…

Fluid Dynamics · Physics 2013-10-14 Christophe Chnafa , Simon Mendez , Franck Nicoud

Global single-valued biomarkers of cardiac function typically used in clinical practice, such as ejection fraction, provide limited insight on the true 3D cardiac deformation process and hence, limit the understanding of both healthy and…

Image and Video Processing · Electrical Eng. & Systems 2023-07-21 Marcel Beetz , Abhirup Banerjee , Vicente Grau

Brightfield time-lapse imaging is widely used in cardiac tissue engineering, yet the absence of standardized, interpretable analytical frameworks limits reproducibility and cross-platform comparison. We present an open, scalable…

Quantitative Methods · Quantitative Biology 2026-04-10 Hiba Kobeissi , Samuel J. DePalma , Javiera Jilberto , David Nordsletten , Brendon M. Baker , Emma Lejeune

We present a geometric framework for aligning white matter fiber tracts. By registering fiber tracts between brains, one expects to see overlap of anatomical structures that often provide meaningful comparisons across subjects. However, the…

Computer Vision and Pattern Recognition · Computer Science 2021-08-10 Andrew Lizarraga , David Lee , Antoni Kubicki , Ashish Sahib , Elvis Nunez , Katherine Narr , Shantanu H. Joshi

We present a novel automated method to segment the myocardium of both left and right ventricles in MRI volumes. The segmentation is consistent in 3D across the slices such that it can be directly used for mesh generation. Two specific…

Computer Vision and Pattern Recognition · Computer Science 2018-03-30 Qiao Zheng , Hervé Delingette , Nicolas Duchateau , Nicholas Ayache

Manual segmentation of the Left Ventricle (LV) is a tedious and meticulous task that can vary depending on the patient, the Magnetic Resonance Images (MRI) cuts and the experts. Still today, we consider manual delineation done by experts as…

Computer Vision and Pattern Recognition · Computer Science 2018-01-09 Alexandre Attia , Sharone Dayan

Intraventricular vector flow mapping (iVFM) is a technique for retrieving 2-D velocity vector fields of blood flow in the left ventricle. This method is based on conventional color Doppler imaging, which makes iVFM compatible with the…

In the field of 3D medical imaging, accurately extracting and representing the blood vessels with curvilinear structures holds paramount importance for clinical diagnosis. Previous methods have commonly relied on discrete representation…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Ziwei Zhao , Zhixing Zhang , Yuhang Liu , Zhao Zhang , Haojun Yu , Dong Wang , Liwei Wang

3D motion estimation from cine cardiac magnetic resonance (CMR) images is important for the assessment of cardiac function and the diagnosis of cardiovascular diseases. Current state-of-the art methods focus on estimating dense…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Qingjie Meng , Wenjia Bai , Declan P O'Regan , and Daniel Rueckert

Congenital heart disease (CHD) encompasses a spectrum of cardiovascular structural abnormalities, often requiring customized treatment plans for individual patients. Computational modeling and analysis of these unique cardiac anatomies can…

Tissues and Organs · Quantitative Biology 2023-11-09 Fanwei Kong , Sascha Stocker , Perry S. Choi , Michael Ma , Daniel B. Ennis , Alison Marsden

Lateral ventricle (LV) shape analysis holds promise as a biomarker for neurological diseases; however, challenges remain due to substantial shape variability across individuals and segmentation difficulties arising from limited MRI…

Computer Vision and Pattern Recognition · Computer Science 2025-08-22 Wonjung Park , Suhyun Ahn , Jinah Park

Cardiopulmonary resuscitation (CPR) is an emergency procedure performed on patients during cardiac and respiratory arrest. This procedure externally activates the cardiac and respiratory systems via the delivery of chest compression and…

Numerical Analysis · Mathematics 2022-06-01 Jafar Moradicheghamahi , Gerard Fortuny , Josep M. López , Joan Herrero , Dolors Puigjaner

Four-dimensional (4D) left ventricular myocardial velocity mapping (MVM) is a cardiac magnetic resonance (CMR) technique that allows assessment of cardiac motion in three orthogonal directions. Accurate and reproducible delineation of the…

Image and Video Processing · Electrical Eng. & Systems 2020-12-23 Yinzhe Wu , Suzan Hatipoglu , Diego Alonso-Álvarez , Peter Gatehouse , David Firmin , Jennifer Keegan , Guang Yang

Two-dimensional echocardiography (2DE) measurements of left ventricle (LV) dimensions are highly significant markers of several cardiovascular diseases. These measurements are often used in clinical care despite suffering from large…

Image and Video Processing · Electrical Eng. & Systems 2019-11-07 Andrew Gilbert , Marit Holden , Line Eikvil , Svein Arne Aase , Eigil Samset , Kristin McLeod

Diffusion magnetic resonance imaging (dMRI) and tractography provide means to study the anatomical structures within the white matter of the brain. When studying tractography data across subjects, it is usually necessary to align, i.e. to…

Machine Learning · Statistics 2016-02-01 Thien Bao Nguyen , Emanuele Olivetti , Paolo Avesani

Reduced-order models based on physics are a popular choice in cardiovascular modeling due to their efficiency, but they may experience reduced accuracy when working with anatomies that contain numerous junctions or pathological conditions.…

Virtual interventions enable the physics-based simulation of device deployment within coronary arteries. This framework allows for counterfactual reasoning by deploying the same device in different arterial anatomies. However, current…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Karim Kadry , Shreya Gupta , Jonas Sogbadji , Michiel Schaap , Kersten Petersen , Takuya Mizukami , Carlos Collet , Farhad R. Nezami , Elazer R. Edelman

Accurate 3D cardiac reconstruction from cine magnetic resonance imaging (cMRI) is crucial for improved cardiovascular disease diagnosis and understanding of the heart's motion. However, current cardiac MRI-based reconstruction technology…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Xiaoxiao He , Chaowei Tan , Ligong Han , Bo Liu , Leon Axel , Kang Li , Dimitris N. Metaxas

Lumped method (Electrical analogy) is a quick and easy way to model human cardiovascular system. In this paper Lumped method is used for simulating a complete model. It describes a 36-vessel model and cardiac system of human body with…

The density-equalizing map, a technique developed for cartogram creation, has been widely applied to data visualization but only for 2D applications. In this work, we propose a novel method called the volumetric density-equalizing reference…

Numerical Analysis · Mathematics 2021-04-06 Gary P. T. Choi , Chris H. Rycroft
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