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Aortic shape analysis plays a key role in cardiovascular diagnostics, treatment planning, and understanding disease progression. We present a robust, fully automated pipeline for aortic shape analysis from cardiac MRI, combining deep…

Tissues and Organs · Quantitative Biology 2025-09-15 Nairouz Shehata , Amr Elsawy , Mohamed Nagy , Muhammad ElMahdy , Mariam Ali , Soha Romeih , Heba Aguib , Magdi Yacoub , Ben Glocker

Usually, clinicians assess the correct hemodynamic behavior and fetal well-being during the gestational age thanks to their professional expertise, with the support of some indices defined for Doppler fetal waveforms. Although this approach…

In the study of shapes of human organs using computational anatomy, variations are found to arise from inter-subject anatomical differences, disease-specific effects, and measurement noise. This paper introduces a stochastic model for…

Computer Vision and Pattern Recognition · Computer Science 2016-12-19 Alexis Arnaudon , Darryl D. Holm , Akshay Pai , Stefan Sommer

Simulated ultrasound image sequences are key for training and validating machine learning algorithms for left ventricular strain estimation. Several simulation pipelines have been proposed to generate sequences with corresponding ground…

Image and Video Processing · Electrical Eng. & Systems 2025-09-08 Thierry Judge , Nicolas Duchateau , Khuram Faraz , Pierre-Marc Jodoin , Olivier Bernard

Diffeomorphic registration using optimal control on the diffeomorphism group and on shape spaces has become widely used since the development of the Large Deformation Diffeomorphic Metric Mapping (LDDMM) algorithm. More recently, a series…

Optimization and Control · Mathematics 2015-03-04 Sylvain Arguillère , Michael Miller , Laurent Younes

Quantitative assessment of cardiac left ventricle (LV) morphology is essential to assess cardiac function and improve the diagnosis of different cardiovascular diseases. In current clinical practice, LV quantification depends on the…

Image and Video Processing · Electrical Eng. & Systems 2020-12-25 Sulaiman Vesal , Mingxuan Gu , Andreas Maier , Nishant Ravikumar

In this paper, the problem of orientation correction in cardiac MRI images is investigated and a framework for orientation recognition via deep neural networks is proposed. For multi-modality MRI, we introduce a transfer learning strategy…

Image and Video Processing · Electrical Eng. & Systems 2022-11-22 Jiyao Liu

Left ventricular (LV) stiffness and contractility, characterized by the end-diastolic and end-systolic pressure-volume relationships (EDPVR & ESPVR), are two important indicators of the performance of the human heart. Although much research…

Medical Physics · Physics 2023-08-22 Yunxiao Zhang , Moritz Kalhöfer-Köchling , Eberhard Bodenschatz , Yong Wang

Two-dimensional representation of 3D anatomical structures is a simple and intuitive way for analysing patient information across populations and image modalities. It also allows convenient visualizations that can be included in clinical…

One of the first steps in the diagnosis of most cardiac diseases, such as pulmonary hypertension, coronary heart disease is the segmentation of ventricles from cardiac magnetic resonance (MRI) images. Manual segmentation of the right…

Image and Video Processing · Electrical Eng. & Systems 2019-08-22 Yaman Dang , Deepak Anand , Amit Sethi

Hyper-trabeculation or non-compaction in the left ventricle of the myocardium (LVNC) is a recently classified form of cardiomyopathy. Several methods have been proposed to quantify the trabeculae accurately in the left ventricle, but there…

Image and Video Processing · Electrical Eng. & Systems 2024-02-13 Gregorio Bernabé , Pilar González-Férez , José M. García , Guillem Casas , Josefa González-Carrillo

Left ventricular segmentation is essential for measuring left ventricular function indices. Segmentation of one or several images requires an initial guess of the contour. It is hypothesized here that creating an initial guess by first…

Computer Vision and Pattern Recognition · Computer Science 2015-10-13 Yael Petrank , Nahum Smirin , Yossi Tsadok , Zvi Friedman , Peter Lysiansky , Dan Adam

Predictive high-fidelity finite element simulations of human cardiac mechanics co\-mmon\-ly require a large number of structural degrees of freedom. Additionally, these models are often coupled with lumped-parameter models of hemodynamics.…

Computational Engineering, Finance, and Science · Computer Science 2020-02-18 Martin R. Pfaller , Maria Cruz Varona , Johannes Lang , Cristóbal Bertoglio , Wolfgang A. Wall

The functional analysis of the left atrium (LA) is important for evaluating cardiac health and understanding diseases like atrial fibrillation. Cine MRI is ideally placed for the detailed 3D characterization of LA motion and deformation but…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Christoforos Galazis , Samuel Shepperd , Emma Brouwer , Sandro Queirós , Ebraham Alskaf , Mustafa Anjari , Amedeo Chiribiri , Jack Lee , Anil A. Bharath , Marta Varela

Automated cardiac segmentation from magnetic resonance imaging datasets is an essential step in the timely diagnosis and management of cardiac pathologies. We propose to tackle the problem of automated left and right ventricle segmentation…

Computer Vision and Pattern Recognition · Computer Science 2017-04-28 Phi Vu Tran

Image-based computational fluid dynamics (CFD) has emerged as a powerful tool to study cardiovascular flows while 2D echocardiography (echo) is the most widely used non-invasive imaging modality for diagnosis of heart disease. Here, echo is…

In computational anatomy, the Large Deformation Diffeomorphic Metric Mapping (LDDMM) framework has become a central tool for modeling smooth, invertible transformations between shapes such as curves or landmarks. In this paper, we extend…

Differential Geometry · Mathematics 2025-11-19 Rayane Mouhli , Thomas Pierron

Heart transplant patients are followed with periodic right heart catheterizations (RHCs) to identify post-transplant complications and guide treatment. Post-transplant positive outcomes are associated with a steady reduction of right…

Tissues and Organs · Quantitative Biology 2019-12-11 Amanda L. Colunga , Karam G. Kim , N. Payton Woodall , Todd F. Dardas , John H. Gennari , Mette S. Olufsen , Brian E. Carlson

Zero-dimensional (0D) cardiovascular models are reduced-order models used to study global circulation dynamics and transport. They provide estimates of biomarkers (such as pressure, flow rates, and concentrations) for surgery planning and…

Numerical Analysis · Mathematics 2025-11-14 John M. Hanna , Pavlos Varsos , Jérôme Kowalski , Lorenzo Sala , Roel Meiburg , Irene E. Vignon-Clementel

Kendall shape spaces are a widely used framework for the statistical analysis of shape data arising from many domains, often requiring the parallel transport as a tool to normalise time series data or transport gradient in optimisation…

Differential Geometry · Mathematics 2021-03-09 Nicolas Guigui , Elodie Maignant , Alain Trouvé , Xavier Pennec
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