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Altered hemodynamics play a key role in cerebrovascular diseases such as aneurysms and stenosis. However, in vivo imaging lacks the spatial resolution required to resolve flow dynamics in small vessels. This study presents an experimental…

Fluid Dynamics · Physics 2026-05-25 Job van Essen , Ahmed Sharaf , Denzel Hopman , Selene Pirola , Paola Fanzio

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

In this paper, a multiscale constitutive framework for one-dimensional blood flow modeling is presented and discussed. By analyzing the asymptotic limits of the proposed model, it is shown that different types of blood propagation phenomena…

Numerical Analysis · Mathematics 2023-12-13 Giulia Bertaglia , Lorenzo Pareschi

Aerosol injectors applied in single-particle diffractive imaging experiments demonstrated their potential in efficiently delivering nanoparticles with high density. Continuous optimization of injector design is crucial for achieving…

In the present article we demonstrate a new hybrid model of tumor growth. Our model is stochastic by tumor population development and strongly deterministic in cell motility dynamics and spatial propagation. In addition, it has excellent…

Other Quantitative Biology · Quantitative Biology 2017-05-03 Yehor Surkov , Ihor Samofalov , Mironenko Anastasia

Solid tumours have the ability to assemble their own vascular network for optimizing their access to the vital nutrients. These new capillaries are morphologically different from normal physiological vessels. In particular, they have a much…

Soft Condensed Matter · Physics 2022-12-07 Davide Riccobelli , Pasquale Ciarletta

Diffusion models (DMs) have emerged as the new state-of-the-art family of deep generative models. To gain deeper insights into the limitations of diffusion models in recommender systems, we investigate the fundamental structural disparities…

Information Retrieval · Computer Science 2025-04-11 Meng Yuan , Yutian Xiao , Wei Chen , Chu Zhao , Deqing Wang , Fuzhen Zhuang

Mathematical models and numerical simulations are widely used in the field of hemodynamics, representing a valuable resource to better understand physiological and pathological processes. The theory behind the phenomenon is closely related…

Fluid Dynamics · Physics 2021-06-15 Giulia Bertaglia , Valerio Caleffi , Alessandro Valiani

We introduce a framework for designing efficient diffusion models for $d$-dimensional symmetric-space Riemannian manifolds, including the torus, sphere, special orthogonal group and unitary group. Existing manifold diffusion models often…

Machine Learning · Computer Science 2025-05-29 Oren Mangoubi , Neil He , Nisheeth K. Vishnoi

Volume visualization is a method that displays three-dimensional (3D) data in two-dimensional (2D) space. Using 3D datasets instead of 2D traditional images improves the visualization of anatomical structures, and volume visualization helps…

The simulation of stochastic reaction-diffusion systems using fine-grained representations can become computationally prohibitive when particle numbers become large. If particle numbers are sufficiently high then it may be possible to…

Quantitative Methods · Quantitative Biology 2020-10-02 Christian A. Yates , Adam George , Armand Jordana , Cameron A. Smith , Andrew B. Duncan , Konstantinos C. Zygalakis

We propose a hybrid diffusion-based augmentation framework to overcome the critical challenge of ultrasound data augmentation in breast ultrasound (BUS) datasets. Unlike conventional diffusion-based augmentations, our approach improves…

Image and Video Processing · Electrical Eng. & Systems 2026-03-31 Farhan Fuad Abir , Sanjeda Sara Jennifer , Niloofar Yousefi , Laura J. Brattain

Automatic tumor segmentation of breast ultrasound (BUS) image is quite challenging due to the complicated anatomic structure of breast and poor image quality. Most tumor segmentation approaches achieve good performance on BUS images…

Computer Vision and Pattern Recognition · Computer Science 2018-06-29 Fei Xu , Min Xian , Yingtao Zhang , Kuan Huang , H. D. Cheng , Boyu Zhang , Jianrui Ding , Chunping Ning , Ying Wang

We present a novel computational modeling framework to numerically investigate fluid-structure interaction in viscous fluids using the phase field embedding method. Each rigid body or elastic structure immersed in the incompressible viscous…

Fluid Dynamics · Physics 2021-09-16 Qi Hong , Qi Wang

Homogenization method is used to analyse the equivalent behavior of transient flow of a passive solute through highly heterogeneous porous media. The flow is governed by a coupled system which includes an elliptic equation and a linear…

Mathematical Physics · Physics 2007-05-23 Brahim Amaziane , Alain Bourgeat , Mladen Jurak

Stochastic simulation methods can be applied successfully to model exact spatio-temporally resolved reaction-diffusion systems. However, in many cases, these methods can quickly become extremely computationally intensive with increasing…

Quantitative Methods · Quantitative Biology 2016-04-29 Jonathan U. Harrison , Christian A. Yates

A major challenge in flow through porous media is to better understand the link between microstructure and macroscale flow and transport. For idealised microstructures, the mathematical framework of homogenisation theory can be used for…

To ensure homogeneous conditions within the complete area of perfused microfluidic bio-reactors, we develop a general design of a continuously feed bio-reactor with uniform perfusion flow. This is achieved by introducing a specific type of…

Fluid Dynamics · Physics 2009-05-20 Fridolin Okkels , Martin Dufva , Henrik Bruus

The generation of 3D molecules requires simultaneously deciding the categorical features~(atom types) and continuous features~(atom coordinates). Deep generative models, especially Diffusion Models (DMs), have demonstrated effectiveness in…

Machine Learning · Computer Science 2023-12-13 Yuxuan Song , Jingjing Gong , Minkai Xu , Ziyao Cao , Yanyan Lan , Stefano Ermon , Hao Zhou , Wei-Ying Ma

Simulating spatiotemporal turbulence with high fidelity remains a cornerstone challenge in computational fluid dynamics (CFD) due to its intricate multiscale nature and prohibitive computational demands. Traditional approaches typically…

Fluid Dynamics · Physics 2024-07-01 Xiantao Fan , Deepak Akhare , Jian-Xun Wang