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Foundation models in healthcare have largely adopted self supervised pretraining objectives inherited from natural language processing and computer vision, emphasizing reconstruction and large scale representation learning prior to…

Machine Learning · Computer Science 2026-03-24 Yang Zhang , Li Fan , Samuel Lawrence , Shi Li

Unstructured information comprises a valuable source of data in clinical records. For text mining in clinical records, concept extraction is the first step in finding assertions and relationships. This study presents a system developed for…

Information Retrieval · Computer Science 2010-12-09 Ning Kang , Rogier Barendse , Zubair Afzal , Bharat Singh , Martijn J. Schuemie , Erik M. van Mulligen , Jan A. Kors

In the era of clinical information explosion, a good strategy for clinical text summarization is helpful to improve the clinical workflow. The ideal summarization strategy can preserve important information in the informative but less…

Computation and Language · Computer Science 2020-03-03 Wei-Hung Weng , Yu-An Chung , Schrasing Tong

Unsupervised pretraining is an integral part of many natural language processing systems, and transfer learning with language models has achieved remarkable results in many downstream tasks. In the clinical application of medical code…

Computation and Language · Computer Science 2022-06-03 Shaoxiong Ji , Matti Hölttä , Pekka Marttinen

Translating the vast data generated by genomic platforms into reliable predictions of clinical outcomes remains a critical challenge in realizing the promise of genomic medicine largely due to small number of independent samples. In this…

Quantitative Methods · Quantitative Biology 2019-04-04 Safoora Yousefi , Amirreza Shaban , Mohamed Amgad , Ramraj Chandradevan , Lee A. D. Cooper

We present an automatic mortality prediction scheme based on the unstructured textual content of clinical notes. Proposing a convolutional document embedding approach, our empirical investigation using the MIMIC-III intensive care database…

Computation and Language · Computer Science 2016-12-05 Paulina Grnarova , Florian Schmidt , Stephanie L. Hyland , Carsten Eickhoff

Clinician scheduling remains a persistent challenge due to limited clinical resources and fluctuating demands. This complexity is especially acute in large academic anesthesiology departments as physicians balance responsibilities across…

Optimization and Control · Mathematics 2025-10-03 Anjali Jha , Wanqing Chen , Maxim Eckmann , Ian Stockwell , Jianwu Wang , Kai Sun

Machine learning models depend on the quality of input data. As electronic health records are widely adopted, the amount of data in health care is growing, along with complaints about the quality of medical notes. We use two prediction…

Computation and Language · Computer Science 2020-12-10 Chao-Chun Hsu , Shantanu Karnwal , Sendhil Mullainathan , Ziad Obermeyer , Chenhao Tan

We present a system that uses a learned autocompletion mechanism to facilitate rapid creation of semi-structured clinical documentation. We dynamically suggest relevant clinical concepts as a doctor drafts a note by leveraging features from…

Machine Learning · Computer Science 2020-07-31 Divya Gopinath , Monica Agrawal , Luke Murray , Steven Horng , David Karger , David Sontag

Introduction: Timely care in a specialised neuro-intensive therapy unit (ITU) reduces mortality and hospital stays, with planned admissions being safer than unplanned ones. However, post-operative care decisions remain subjective. This…

Early diagnosis of disease can lead to improved health outcomes, including higher survival rates and lower treatment costs. With the massive amount of information available in electronic health records (EHRs), there is great potential to…

Machine Learning · Computer Science 2022-08-02 Asem Alaa , Erik Mayer , Mauricio Barahona

Clinicians spend a significant amount of time inputting free-form textual notes into Electronic Health Records (EHR) systems. Much of this documentation work is seen as a burden, reducing time spent with patients and contributing to…

Computation and Language · Computer Science 2018-08-09 Peter J. Liu

Nowadays, in many scientific and industrial fields there is an increasing need for estimating treatment effects and answering causal questions. The key for addressing these problems is the wealth of observational data and the processes for…

Machine Learning · Statistics 2022-05-24 Niki Kiriakidou , Christos Diou

Clinical notes in healthcare facilities are tagged with the International Classification of Diseases (ICD) code; a list of classification codes for medical diagnoses and procedures. ICD coding is a challenging multilabel text classification…

Computation and Language · Computer Science 2023-06-02 Thanh-Tung Nguyen , Viktor Schlegel , Abhinav Kashyap , Stefan Winkler

Objective:Develop and validate an algorithm for analyzing the layout of PDF clinical documents to improve the performance of downstream natural language processing tasks. Materials and Methods: We designed an algorithm to process clinical…

Computation and Language · Computer Science 2023-05-24 Christel Gérardin , Perceval Wajsbürt , Basile Dura , Alice Calliger , Alexandre Moucher , Xavier Tannier , Romain Bey

Many recent studies use machine learning to predict a small number of ICD-9-CM codes. In practice, on the other hand, physicians have to consider a broader range of diagnoses. This study aims to put these previously incongruent evaluation…

Applications · Statistics 2020-06-25 Gil Alon , Elizabeth Chen , Guergana Savova , Carsten Eickhoff

High hospital readmission rates are associated with significant costs and health risks for patients. Therefore, it is critical to develop predictive models that can support clinicians to determine whether or not a patient will return to the…

Machine Learning · Computer Science 2025-04-01 Tiago Almeida , Plinio Moreno , Catarina Barata

Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing scenarios, particularly in simulating domain-specific experts using tailored prompts. This ability enables LLMs to adopt the persona of individuals with…

Artificial Intelligence · Computer Science 2025-01-14 Xinyao Ma , Rui Zhu , Zihao Wang , Jingwei Xiong , Qingyu Chen , Haixu Tang , L. Jean Camp , Lucila Ohno-Machado

The association between preoperative cognitive status and surgical outcomes is a critical, yet scarcely explored area of research. Linking intraoperative data with postoperative outcomes is a promising and low-cost way of evaluating…

Large Language Models have advanced clinical text classification, but their opaque predictions remain a critical barrier to practical adoption in research and clinical settings where investigators and physicians need to understand which…

Computation and Language · Computer Science 2025-11-18 Karthikeyan K , Raghuveer Thirukovalluru , David Carlson
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