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In this paper we introduce a novel method to conduct inference with models defined through a continuous-time Markov process, and we apply these results to a classical stochastic SIR model as a case study. Using the inverse-size expansion of…

Applications · Statistics 2011-11-10 Marcos A. Capistrán , J. Andrés Christen , Jorge X. Velasco-Hernández

Reliable estimation of spatio-temporal trends in population-level HIV incidence is becoming an increasingly critical component of HIV prevention policy-making. However, direct measurement is nearly impossible. Current, widely used models…

Applications · Statistics 2019-12-04 Timothy M Wolock , Seth R Flaxman , Jeffrey W Eaton

Spatiotemporal data analysis with massive zeros is widely used in many areas such as epidemiology and public health. We use a Bayesian framework to fit zero-inflated negative binomial models and employ a set of latent variables from…

Methodology · Statistics 2024-02-08 Qing He , Hsin-Hsiung Huang

Multi-state models are frequently applied for representing processes evolving through a discrete set of state. Important classes of multi-state models arise when transitions between states may depend on the time since entry into the current…

Methodology · Statistics 2022-02-28 Rosario Barone , Andrea Tancredi

In this paper, we explore whether the infection-rate of a disease can serve as a robust monitoring variable in epidemiological surveillance algorithms. The infection-rate is dependent on population mixing patterns that do not vary…

Applications · Statistics 2024-07-17 Wyatt Bridgman , Cosmin Safta , Jaideep Ray

Our method extends the application of random spanning trees to cases where the response variable belongs to the exponential family, making it suitable for a wide range of real-world scenarios, including non-Gaussian likelihoods. The…

Methodology · Statistics 2024-07-18 Ruiman Zhong , Erick A. Chacón-Montalván , Paula Moraga

An age structured mathematical model with time dependent parameters is developed to investigate the dynamics of dengue transmission. Its properties are thoroughly analyzed in the first part of this work, as for example its disease free…

Populations and Evolution · Quantitative Biology 2025-11-21 Ihtisham Ul Haq , Serge Richard

In retrospective assessments, internet news reports have been shown to capture early reports of unknown infectious disease transmission prior to official laboratory confirmation. In general, media interest and reporting peaks and wanes…

Social and Information Networks · Computer Science 2016-06-02 Saurav Ghosh , Prithwish Chakraborty , Elaine O. Nsoesie , Emily Cohn , Sumiko R. Mekaru , John S. Brownstein , Naren Ramakrishnan

Routine public health surveillance of notifiable infectious diseases gives rise to weekly counts of reported cases -- possibly stratified by region and/or age group. We investigate how an age-structured social contact matrix can be…

Methodology · Statistics 2017-05-12 Sebastian Meyer , Leonhard Held

We develop a mathematical framework to study the economic impact of infectious diseases by integrating epidemiological dynamics with a kinetic model of wealth exchange. The multi-agent description leads to study the evolution over time of a…

Physics and Society · Physics 2020-08-12 G. Dimarco , L. Pareschi , G. Toscani , M. Zanella

Continuous-time multistate models are widely used for analyzing interval-censored data on disease progression over time. Sometimes, diseases manifest differently and what appears to be a coherent collection of symptoms is the expression of…

Methodology · Statistics 2024-10-08 Yidan Shi , Leilei Zeng , Mary E. Thompson , Suzanne L. Tyas

In network-based SIS models of infectious disease transmission, infection can only occur between directly connected individuals. This constraint naturally gives rise to spatial correlations between the states of neighboring nodes, as the…

Statistical Mechanics · Physics 2026-03-18 Alexander Leibenzon , Samuel W. S. Johnson , Ruth E. Baker , Michael Assaf

Testing symptomatic individuals for a disease can deliver treatment resources, if tests' results turn positive, which speeds up their treatment and might also decrease individuals' contacts to other ones. An imperfect test, however, might…

Populations and Evolution · Quantitative Biology 2015-06-25 Daniel A. M. Villela

We study the random times between successive cases in a transmission chain of infectious diseases with asymptomatic carriers. We derive the probability distribution of this generation time (in days) from a discrete-time epidemic model with…

Populations and Evolution · Quantitative Biology 2026-04-16 Jordi Ripoll , Joan Saldaña

In this work we propose a novel space-dependent multiscale model for the spread of infectious diseases in a two-dimensional spatial context on realistic geographical scenarios. The model couples a system of kinetic transport equations…

Numerical Analysis · Mathematics 2020-12-21 Walter Boscheri , Giacomo Dimarco , Lorenzo Pareschi

In this paper we study disease spread over a randomly switched network, which is modeled by a stochastic switched differential equation based on the so called $N$-intertwined model for disease spread over static networks. Assuming that all…

Systems and Control · Computer Science 2016-11-04 Masaki Ogura , Victor M. Preciado

This article introduces new methods for inference with count data registered on a set of aggregation units. Such data are omnipresent in epidemiology due to confidentiality issues: it is much more common to know the county in which an…

Methodology · Statistics 2017-04-20 Benjamin M. Taylor , Ricardo Andrade-Pacheco , Hugh J. W. Sturrock

Detection of patient-zero can give new insights to the epidemiologists about the nature of first transmissions into a population. In this paper, we study the statistical inference problem of detecting the source of epidemics from a snapshot…

Social and Information Networks · Computer Science 2015-06-24 Nino Antulov-Fantulin , Alen Lancic , Tomislav Smuc , Hrvoje Stefancic , Mile Sikic

In medical research, understanding changes in outcome measurements is crucial for inferring shifts in health conditions. However, traditional methods often struggle with large, irregularly longitudinal data and fail to account for the…

Applications · Statistics 2025-03-13 Yu Luo , Chris Sherlock

In employing spatial regression models for counts, we usually meet two issues. First, ignoring the inherent collinearity between covariates and the spatial effect would lead to causal inferences. Second, real count data usually reveal over…

Methodology · Statistics 2021-05-21 Mahsa Nadifar , Hossein Baghishani , Afshin Fallah