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Glaucoma is the leading cause of irreversible but preventable blindness in the world. Its major treatable risk factor is the intra-ocular pressure, although other biomarkers are being explored to improve the understanding of the…

Computer Vision and Pattern Recognition · Computer Science 2018-10-26 José Ignacio Orlando , João Barbosa Breda , Karel van Keer , Matthew B. Blaschko , Pablo J. Blanco , Carlos A. Bulant

Uncertainty pervades through the modern robotic autonomy stack, with nearly every component (e.g., sensors, detection, classification, tracking, behavior prediction) producing continuous or discrete probabilistic distributions. Trajectory…

Robotics · Computer Science 2022-07-13 Boris Ivanovic , Yifeng Lin , Shubham Shrivastava , Punarjay Chakravarty , Marco Pavone

Uncertainty propagation in nonlinear dynamic systems remains an outstanding problem in scientific computing and control. Numerous approaches have been developed, but are limited in their capability to tackle problems with more than a few…

Dynamical Systems · Mathematics 2019-11-22 Tenavi Nakamura-Zimmerer , Daniele Venturi , Qi Gong , Wei Kang

Many applications in aerodynamics, particularly in closed-loop control, depend on sensors to estimate the evolving state of the flow. This estimation task is inherently accompanied by uncertainty due to the noisy measurements of sensors or…

Fluid Dynamics · Physics 2026-01-07 Jeff D. Eldredge , Hanieh Mousavi

Many engineering systems are subject to spatially distributed uncertainty, i.e. uncertainty that can be modeled as a random field. Altering the mean or covariance of this uncertainty will in general change the statistical distribution of…

Optimization and Control · Mathematics 2014-07-09 Eric Dow , Qiqi Wang

In the context of numerical simulations of the vascular system, local geometric uncertainties have not yet been examined in sufficient detail due to model complexity and the associated large numerical effort. Such uncertainties are related…

Understanding human eye behavior involves intricate interactions between physical phenomena such as heat transfer and fluid dynamics. Accurate computational models are vital for comprehending ocular diseases and therapeutic…

Analysis of PDEs · Mathematics 2024-05-01 Thomas Saigre , Christophe Prud'Homme , Marcela Szopos , Vincent Chabannes

This paper introduces a global uncertainty propagation scheme for rigid body dynamics, through a combination of numerical parametric uncertainty techniques, noncommutative harmonic analysis, and geometric numerical integration. This method…

Dynamical Systems · Mathematics 2008-03-12 Taeyoung Lee , Melvin Leok , N. Harris McClamroch

Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…

Computer simulations of inhomogeneous soft matter systems often require accurate methods for computing the local pressure. We present a simple derivation, based on the virial relation, of two equivalent expressions for the local (atomistic)…

Soft Condensed Matter · Physics 2015-06-03 Thomas Lion , Rosalind J. Allen

Patient-specific computational modeling is a popular, non-invasive method to answer medical questions. Medical images are used to extract geometric domains necessary to create these models, providing a predictive tool for clinicians.…

Autonomous vehicles (AVs) are being increasingly deployed in urban environments. In order to operate safely and reliably, AVs need to account for the inherent uncertainty associated with perceiving the world through sensor data and…

As an important method of handling potential uncertainties in numerical simulations, ensemble simulation has been widely applied in many disciplines. Visualization is a promising and powerful ensemble simulation analysis method. However,…

Graphics · Computer Science 2020-11-04 Mingdong Zhang , Li Chen , Quan Li , Xiaoru Yuan , Junhai Yong

In this paper, we consider discrete-time non-linear stochastic dynamical systems with additive process noise in which both the initial state and noise distributions are uncertain. Our goal is to quantify how the uncertainty in these…

Systems and Control · Electrical Eng. & Systems 2025-05-19 Steven Adams , Eduardo Figueiredo , Luca Laurenti

In nuclear engineering studies, uncertainty and sensitivity analyses of simulation computer codes can be faced to the complexity of the input and/or the output variables. If these variables represent a transient or a spatial phenomenon, the…

Applications · Statistics 2023-12-05 Anne-Laure Popelin , Bertrand Iooss

Predictive uncertainty estimation remains a challenging problem precluding the use of deep neural networks as subsystems within safety-critical applications. Aleatoric uncertainty is a component of predictive uncertainty that cannot be…

Machine Learning · Computer Science 2023-12-12 Angel Daruna , Yunye Gong , Abhinav Rajvanshi , Han-Pang Chiu , Yi Yao

Sensitivity analysis is concerned with understanding how the model output depends on uncertainties (variances) in inputs and then identifies which inputs are important in contributing to the prediction imprecision. Uncertainty determination…

Physics and Society · Physics 2017-01-04 Yueying Zhu , Qiuping Alexandre Wang , Wei Li , Xu Cai

Fluorescein is perhaps the most commonly used substance to visualize tear film thickness and dynamics; better understanding of this process aids understanding of dry eye syndrome which afflicts millions of people. We study a mathematical…

Quantitative Methods · Quantitative Biology 2016-11-01 Longfei Li , R. J. Braun , W. D. Henshaw , P. E. King-Smith

Surrogate models are statistical or conceptual approximations for more complex simulation models. In this context, it is crucial to propagate the uncertainty induced by limited simulation budget and surrogate approximation error to…

Machine Learning · Statistics 2026-01-27 Philipp Reiser , Javier Enrique Aguilar , Anneli Guthke , Paul-Christian Bürkner

In this paper we will address the problem of developing mathematical models for the numerical simulation of the human circulatory system. In particular, we will focus our attention on the problem of haemodynamics in large human arteries.

Dynamical Systems · Mathematics 2007-05-23 Alfio Quarteroni