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Despite the unprecedented performance of deep neural networks (DNNs) in computer vision, their practical application in the diagnosis and prognosis of cancer using medical imaging has been limited. One of the critical challenges for…

Machine Learning · Computer Science 2023-04-27 Lennart Brocki , Neo Christopher Chung

The treatment planning process for patients with head and neck (H&N) cancer is regarded as one of the most complicated due to large target volume, multiple prescription dose levels, and many radiation-sensitive critical structures near the…

Medical Physics · Physics 2019-03-27 Dan Nguyen , Xun Jia , David Sher , Mu-Han Lin , Zohaib Iqbal , Hui Liu , Steve Jiang

Breast cancer is one of the most threatening diseases in women's life; thus, the early and accurate diagnosis plays a key role in reducing the risk of death in a patient's life. Mammography stands as the reference technique for breast…

Machine Learning · Computer Science 2023-05-05 Juan Zuluaga-Gomez

Medical imaging technologies have undergone extensive development, enabling non-invasive visualization of clinical information. The traditional review of medical images by clinicians remains subjective, time-consuming, and prone to human…

Image and Video Processing · Electrical Eng. & Systems 2024-07-22 Elizaveta Lavrova , Henry C. Woodruff , Hamza Khan , Eric Salmon , Philippe Lambin , Christophe Phillips

The burgeoning discipline of computational pathology shows promise in harnessing whole slide images (WSIs) to quantify morphological heterogeneity and develop objective prognostic modes for human cancers. However, progress is impeded by the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Chao Tu , Kun Huang , Jie Zhang , Qianjin Feng , Yu Zhang , Zhenyuan Ning

Tumor volume segmentation on MRI is a challenging and time-consuming process that is performed manually in typical clinical settings. This work presents an approach to automated delineation of head and neck tumors on MRI scans, developed in…

Image and Video Processing · Electrical Eng. & Systems 2025-01-10 Andrei Iantsen

Deep learning has shown remarkable results for image analysis and is expected to aid individual treatment decisions in health care. To achieve this, deep learning methods need to be promoted from the level of mere associations to being able…

Machine Learning · Computer Science 2022-05-02 Wouter A. C. van Amsterdam , Marinus J. C. Eijkemans

Background. Radiomic features, derived from a region of interest (ROI) in medical images, are valuable as prognostic factors. Selecting an appropriate ROI is critical, and many recent studies have focused on leveraging multiple ROIs by…

Radiomics aims to extract and analyze large numbers of quantitative features from medical images and is highly promising in staging, diagnosing, and predicting outcomes of cancer treatments. Nevertheless, several challenges need to be…

Machine Learning · Computer Science 2017-10-09 Zhiguo Zhou , Zhi-Jie Zhou , Hongxia Hao , Shulong Li , Xi Chen , You Zhang , Michael Folkert , Jing Wang

Cancer, in general, is very deadly. Timely treatment of any cancer is the key to saving a life. Skin cancer is no exception. There have been thousands of Skin Cancer cases registered per year all over the world. There have been 123,000…

Computer Vision and Pattern Recognition · Computer Science 2020-06-16 Kaushil Mangaroliya , Mitt Shah

Radiomics is an emerging area of medical imaging data analysis particularly for cancer. It involves the conversion of digital medical images into mineable ultra-high dimensional data. Machine learning algorithms are widely used in radiomics…

Methodology · Statistics 2023-10-11 Ismaïla Baldé , Debashis Ghosh

Prognostication for lung cancer, a leading cause of mortality, remains a complex task, as it needs to quantify the associations of risk factors and health events spanning a patient's entire life. One challenge is that an individual's…

Machine Learning · Statistics 2025-08-28 Stephen Salerno , Yi Li

Background and aim: This study aimed to predict methylation status of the O-6 methyl guanine-DNA methyl transferase (MGMT) gene promoter status by using MRI radiomics features, as well as univariate and multivariate analysis. Material and…

Radiomics is a nascent field in quantitative imaging that uses advanced algorithms and considerable computing power to describe tumor phenotypes, monitor treatment response, and assess normal tissue toxicity quantifiably. Remarkable…

Medical Physics · Physics 2019-11-26 Jiwoong Jeong , Arif Ali , Tian Liu , Hui Mao , Walter J. Curran , Xiaofeng Yang

Pancreatic Ductal Adenocarcinoma (PDAC) is one of the most aggressive cancers with an extremely poor prognosis. Radiomics has shown prognostic ability in multiple types of cancer including PDAC. However, the prognostic value of traditional…

Quantitative Methods · Quantitative Biology 2019-08-22 Yucheng Zhang , Edrise M. Lobo-Mueller , Paul Karanicolas , Steven Gallinger , Masoom A. Haider , Farzad Khalvati

Quantitative analysis of brain tumors is critical for clinical decision making. While manual segmentation is tedious, time consuming and subjective, this task is at the same time very challenging to solve for automatic segmentation methods.…

Computer Vision and Pattern Recognition · Computer Science 2018-03-01 Fabian Isensee , Philipp Kickingereder , Wolfgang Wick , Martin Bendszus , Klaus H. Maier-Hein

Several machine learning techniques for accurate detection of skin cancer from medical images have been reported. Many of these techniques are based on pre-trained convolutional neural networks (CNNs), which enable training the models based…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Aqsa Saeed Qureshi , Teemu Roos

Thyroid cancer is an increasing global health concern that requires advanced diagnostic methods. The application of AI and radiomics to thyroid cancer diagnosis is examined in this review. A review of multiple databases was conducted in…

Cancer survival prediction from multi-omics data remains challenging because prognostic signals are high-dimensional, heterogeneous, and distributed across interacting genes and pathways. We propose PathMoG, a pathway-centric modular graph…

Machine Learning · Computer Science 2026-04-28 Di Wang , Chupei Tang , Junxiao Kong , Jixiu Zhai , Moyu Tang , Tianchi Lu

Purpose: To identify optimal classification methods for computed tomography (CT) radiomics-based preoperative prediction of clear cells renal cell carcinoma (ccRCC) grade. Methods and material: Seventy one ccRCC patients were included in…