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Radiomics is an exciting new area of texture research for extracting quantitative and morphological characteristics of pathological tissue. However, to date, only single images have been used for texture analysis. We have extended radiomic…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Vishwa S. Parekh , John Laterra , Chetan Bettegowda , Alex E. Bocchieri , Jay J. Pillai , Michael A. Jacobs

Cancer histology reveals disease progression and associated molecular processes, and contains rich phenotypic information that is predictive of outcome. In this paper, we developed a computational approach based on deep learning to predict…

Image and Video Processing · Electrical Eng. & Systems 2019-09-20 Saima Rathore , Muhammad Aksam Iftikhar , Zissimos Mourelatos

The current cancer treatment practice collects multimodal data, such as radiology images, histopathology slides, genomics and clinical data. The importance of these data sources taken individually has fostered the recent raise of radiomics…

Machine Learning · Computer Science 2023-06-16 Matteo Tortora , Ermanno Cordelli , Rosa Sicilia , Lorenzo Nibid , Edy Ippolito , Giuseppe Perrone , Sara Ramella , Paolo Soda

Purpose: To develop a novel deep-learning model that integrates radiomics analysis in a multi-dimensional feature fusion workflow for glioblastoma (GBM) post-resection survival prediction. Methods: A cohort of 235 GBM patients with complete…

Medical Physics · Physics 2022-03-14 Zongsheng Hu , Zhenyu Yang , Haozhao Zhang , Eugene Vaios , Kyle Lafata , Fang-Fang Yin , Chunhao Wang

The application of artificial intelligence (AI) in medical imaging has revolutionized diagnostic practices, enabling advanced analysis and interpretation of radiological data. This study presents a comprehensive evaluation of…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Zhijin He , Alan B. McMillan

Background: Radiomics shows promise in characterizing glioblastoma, but its added value over clinical and molecular predictors has yet to be proven. This study assessed the added value of conventional radiomics (CR) and deep learning (DL)…

Renal cell carcinoma represents a significant global health challenge with a low survival rate. This research aimed to devise a comprehensive deep-learning model capable of predicting survival probabilities in patients with renal cell…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Maryamalsadat Mahootiha , Hemin Ali Qadir , Jacob Bergsland , Ilangko Balasingham

Accurately predicting early recurrence in brain tumor patients following surgical resection remains a clinical challenge. This study proposes a multi-modal machine learning framework that integrates structural MRI features with clinical…

Machine Learning · Computer Science 2025-09-03 Cheng Cheng , Zeping Chen , Rui Xie , Peiyao Zheng , Xavier Wang

Radiomic models have been shown to outperform clinical data for outcome prediction in glioblastoma (GBM). However, clinical implementation is limited by lack of parameters standardization. We aimed to compare nine machine learning…

Radiomics analysis has achieved great success in recent years. However, conventional Radiomics analysis suffers from insufficiently expressive hand-crafted features. Recently, emerging deep learning techniques, e.g., convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Jiancheng Yang , Rongyao Fang , Bingbing Ni , Yamin Li , Yi Xu , Linguo Li

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

Personalized head and neck cancer therapeutics have greatly improved survival rates for patients, but are often leading to understudied long-lasting symptoms which affect quality of life. Sequential rule mining (SRM) is a promising…

Human-Computer Interaction · Computer Science 2023-09-28 Carla Floricel , Andrew Wentzel , Abdallah Mohamed , C. David Fuller , Guadalupe Canahuate , G. Elisabeta Marai

Head and neck cancers are the fifth most common cancer worldwide, and recently, analysis of Positron Emission Tomography (PET) and Computed Tomography (CT) images has been proposed to identify patients with a prognosis. Even though the…

Image and Video Processing · Electrical Eng. & Systems 2022-12-01 Vajira Thambawita , Andrea M. Storås , Steven A. Hicks , Pål Halvorsen , Michael A. Riegler

The prediction of pancreatic ductal adenocarcinoma therapy response is a clinically challenging and important task in this high-mortality tumour entity. The training of neural networks able to tackle this challenge is impeded by a lack of…

Image and Video Processing · Electrical Eng. & Systems 2023-03-31 Alexander Ziller , Ayhan Can Erdur , Friederike Jungmann , Daniel Rueckert , Rickmer Braren , Georgios Kaissis

In this work, we develop an attention convolutional neural network (CNN) to segment brain tumors from Magnetic Resonance Images (MRI). Further, we predict the survival rate using various machine learning methods. We adopt a 3D UNet…

Image and Video Processing · Electrical Eng. & Systems 2021-04-05 Mobarakol Islam , Vibashan VS , V Jeya Maria Jose , Navodini Wijethilake , Uppal Utkarsh , Hongliang Ren

Collectively, lung cancer, breast cancer and melanoma was diagnosed in over 535,340 people out of which, 209,400 deaths were reported [13]. It is estimated that over 600,000 people will be diagnosed with these forms of cancer in 2015. Most…

Machine Learning · Computer Science 2015-09-29 Mohnish Chakravarti , Tanay Kothari

Background: Clear cell renal cell carcinoma (ccRCC) is the most common renal-related tumor with high heterogeneity. There is still an urgent need for novel diagnostic and prognostic biomarkers for ccRCC. Methods: We proposed a…

Image and Video Processing · Electrical Eng. & Systems 2023-01-13 Siteng Chen , Xiyue Wang , Jun Zhang , Liren Jiang , Ning Zhang , Feng Gao , Wei Yang , Jinxi Xiang , Sen Yang , Junhua Zheng , Xiao Han

Cancer remains a leading cause of death worldwide, necessitating personalized treatment approaches to improve outcomes. Theranostics, combining molecular-level imaging with targeted therapy, offers potential for precision oncology but…

Computational Engineering, Finance, and Science · Computer Science 2025-05-16 Binesh Sadanandan , Vahid Behzadan

In oncology, recurrence after treatment is one of the major challenges, related to patients' survival and quality of life. Conventionally, prediction of cancer relapse has always relied on clinical observation with statistical model…

Machine Learning · Computer Science 2025-02-25 Muhammad Umer Qayyum , Muhammad Fahad , Nasrullah Abbasi

Multiple Myeloma (MM) is a blood cancer implying bone marrow involvement, renal damages and osteolytic lesions. The skeleton involvement of MM is at the core of the present paper, exploiting radiomics and artificial intelligence to identify…

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