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Computer-aided methods for analyzing white blood cells (WBC) have become widely popular due to the complexity of the manual process. Recent works have shown highly accurate segmentation and detection of white blood cells from microscopic…

Image and Video Processing · Electrical Eng. & Systems 2019-10-03 Changhun Jung , Mohammed Abuhamad , Jumabek Alikhanov , Aziz Mohaisen , Kyungja Han , DaeHun Nyang

Detecting and classifying cells in histopathology H\&E stained whole-slide images is a core task in computational pathology, as it provides valuable insight into the tumor microenvironment. In this work we investigate the impact of ground…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Lydia A. Schoenpflug , Viktor H. Koelzer

Human immune system contains white blood cells (WBC) that are good indicator of many diseases like bacterial infections, AIDS, cancer, spleen, etc. White blood cells have been sub classified into four types: monocytes, lymphocytes,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Rabia Asghar , Arslan Shaukat , Usman Akram , Rimsha Tariq

Pathological diagnosis is the gold standard for cancer diagnosis, but it is labor-intensive, in which tasks such as cell detection, classification, and counting are particularly prominent. A common solution for automating these tasks is…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Anyu Mao , Jialun Wu , Xinrui Bao , Zeyu Gao , Tieliang Gong , Chen Li

Accurately and quickly binuclear cell (BC) detection plays a significant role in predicting the risk of leukemia and other malignant tumors. However, manual microscopy counting is time-consuming and lacks objectivity. Moreover, with the…

Computer Vision and Pattern Recognition · Computer Science 2022-08-29 Baomin Wang , Geng Hu , Dan Chen , Lihua Hu , Cheng Li , Yu An , Guiping Hu , Guang Jia

Recognizing the types of white blood cells (WBCs) in microscopic images of human blood smears is a fundamental task in the fields of pathology and hematology. Although previous studies have made significant contributions to the development…

Image and Video Processing · Electrical Eng. & Systems 2023-05-22 Satoshi Tsutsui , Zhengyang Su , Bihan Wen

This paper proposes a novel automatic classification framework for the recognition of five types of white blood cells. Segmenting complete white blood cells from blood smears images and extracting advantageous features from them remain…

Computer Vision and Pattern Recognition · Computer Science 2020-09-07 Na Dong , Meng-die Zhai , Jian-fang Chang , Chun-ho Wu

The automatic detection of White Blood Cells (WBC) still remains as an unsolved issue in medical imaging. The analysis of WBC images has engaged researchers from fields of medicine and computer vision alike. Since WBC can be approximated by…

Computer Vision and Pattern Recognition · Computer Science 2014-06-30 Erik Cuevas , Margarita Diaz , Miguel Manzanares , Daniel Zaldivar , Marco Perez

The grade of clear cell renal cell carcinoma (ccRCC) is a critical prognostic factor, making ccRCC nuclei grading a crucial task in RCC pathology analysis. Computer-aided nuclei grading aims to improve pathologists' work efficiency while…

Image and Video Processing · Electrical Eng. & Systems 2021-06-22 Zeyu Gao , Jiangbo Shi , Xianli Zhang , Yang Li , Haichuan Zhang , Jialun Wu , Chunbao Wang , Deyu Meng , Chen Li

White blood cells (WBC) are important parts of our immune system, and they protect our body against infections by eliminating viruses, bacteria, parasites and fungi. The number of WBC types and the total number of WBCs provide important…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Sibasish Dhibar

White blood cells (WBCs) are the most diverse cell types observed in the healing process of injured skeletal muscles. In the course of healing, WBCs exhibit dynamic cellular response and undergo multiple protein expression changes. The…

Image and Video Processing · Electrical Eng. & Systems 2024-09-12 Yang Jiao , Hananeh Derakhshan , Barbara St. Pierre Schneider , Emma Regentova , Mei Yang

Nuclei classification is a critical step in computer-aided diagnosis with histopathology images. In the past, various methods have employed graph neural networks (GNN) to analyze cell graphs that model inter-cell relationships by…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Wei Lou , Guanbin Li , Xiang Wan , Haofeng Li

In agricultural management, precise Ground Truth (GT) data is crucial for accurate Machine Learning (ML) based crop classification. Yet, issues like crop mislabeling and incorrect land identification are common. We propose a multi-level GT…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Sanayya A , Amoolya Shetty , Abhijeet Sharma , Venkatesh Ravichandran , Masthan Wali Gosuvarapalli , Sarthak Jain , Priyamvada Nanjundiah , Ujjal Kr Dutta , Divya Sharma

White blood cell (WBC) classification is fundamental for hematology applications such as infection assessment, leukemia screening, and treatment monitoring. However, real-world WBC datasets present substantial appearance variations caused…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Luu Le , Hoang-Loc Cao , Ha-Hieu Pham , Thanh-Huy Nguyen , Ulas Bagci

Background: The existence of different basal cell carcinoma (BCC) clinical criteria cannot be objectively validated. An adequate ground-truth is needed to train an artificial intelligence (AI) tool that explains the BCC diagnosis by…

Quantitative Methods · Quantitative Biology 2025-10-06 Francisca Silva-Clavería , Carmen Serrano , Iván Matas , Amalia Serrano , Tomás Toledo-Pastrana , Begoña Acha

Accurate classification of blood cells plays a key role in improving automated blood analysis for both medical and veterinary applications. This work presents a two-stage deep clustering method for classifying blood cells from…

Quantitative Methods · Quantitative Biology 2025-09-25 Mihaela Macarie-Ancau , Adrian Groza

Leukemia (blood cancer) is an unusual spread of White Blood Cells or Leukocytes (WBCs) in the bone marrow and blood. Pathologists can diagnose leukemia by looking at a person's blood sample under a microscope. They identify and categorize…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Mohammad Zolfaghari , Hedieh Sajedi

The accurate classification of white blood cells and related blood components is crucial for medical diagnoses. While traditional manual examinations and automated hematology analyzers have been widely used, they are often slow and prone to…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Alexander Kim , Ryan Kim

Skeleton Ground Truth (GT) is critical to the success of supervised skeleton extraction methods, especially with the popularity of deep learning techniques. Furthermore, we see skeleton GTs used not only for training skeleton detectors with…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Cong Yang , Bipin Indurkhya , John See , Bo Gao , Yan Ke , Zeyd Boukhers , Zhenyu Yang , Marcin Grzegorzek

Diagnosis of hematological malignancies depends on accurate identification of white blood cells in peripheral blood smears. Deep learning techniques are emerging as a viable solution to scale and optimize this process by automatic cell…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Michael Deutges , Ario Sadafi , Nassir Navab , Carsten Marr
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