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In the realm of drug discovery, DNA-encoded library (DEL) screening technology has emerged as an efficient method for identifying high-affinity compounds. However, DEL screening faces a significant challenge: noise arising from nonspecific…

Quantitative Methods · Quantitative Biology 2024-09-11 Chunbin Gu , Mutian He , Hanqun Cao , Guangyong Chen , Chang-yu Hsieh , Pheng Ann Heng

Fault tolerance is a prerequisite for scalable quantum computing. Architectures based on 2D topological codes are effective for near-term implementations of fault tolerance. To obtain high performance with these architectures, we require a…

Quantum Physics · Physics 2018-10-23 Ben Criger , Imran Ashraf

Contemporary quantum computers are inherently noisy, posing significant challenges for the development and testing of quantum software. Simplified or outdated noise assumptions can lead to incorrect assessments of program correctness,…

Due to the redundant nature of DNA synthesis and sequencing technologies, a basic model for a DNA storage system is a multi-draw "shuffling-sampling" channel. In this model, a random number of noisy copies of each sequence is observed at…

Information Theory · Computer Science 2021-12-06 Kel Levick , Reinhard Heckel , Ilan Shomorony

Quantum error correction is crucial for protecting quantum information against decoherence. Traditional codes like the surface code require substantial overhead, making them impractical for near-term, early fault-tolerant devices. We…

Quantum Physics · Physics 2026-04-13 Nico Meyer , Christopher Mutschler , Andreas Maier , Daniel D. Scherer

We consider a distributed detection problem within a wireless sensor network (WSN), where a substantial number of sensors cooperate to detect the existence of sparse stochastic signals. To achieve a trade-off between detection performance…

Signal Processing · Electrical Eng. & Systems 2024-11-07 Linlin Mao , Shefeng Yan , Zeping Sui , Hongbin Li

We propose a novel optimization-based decoding algorithm for LDPC-coded massive MIMO channels. The proposed decoding algorithm is based on a proximal gradient method for solving an approximate maximum a posteriori (MAP) decoding problem.…

Information Theory · Computer Science 2021-02-11 Tadashi Wadayama , Satoshi Takabe

In this work we study the single-shot performance of higher dimensional hypergraph product codes decoded using belief-propagation and ordered-statistics decoding [Panteleev and Kalachev, 2021]. We find that decoding data qubit and syndrome…

Quantum Physics · Physics 2023-06-28 Oscar Higgott , Nikolas P. Breuckmann

Maximum distance separable (MDS) array codes constitute an important class of error-correcting codes due to their optimal distance properties and their relevance in distributed storage systems. In this paper, we investigate the construction…

Fine-grained image hashing is a challenging problem due to the difficulties of discriminative region localization and hash code generation. Most existing deep hashing approaches solve the two tasks independently. While these two tasks are…

Computer Vision and Pattern Recognition · Computer Science 2019-11-20 Haien Zeng , Hanjiang Lai , Jian Yin

Metagenomic taxonomic annotation aims to identify the microbial origins of DNA fragments in environmental samples. Traditional methods that rely on sequence similarity are often constrained by the high microbial diversity and the…

Machine Learning · Computer Science 2026-05-29 Rongye Ye , Lun Li , Zheng Luo , Yiran Zhan , Shuhui Song

Many satellite communication systems operating today employ low cost upconverters or downconverters which create phase noise. This noise can severely limit the information rate of the system and pose a serious challenge for the detection…

Information Theory · Computer Science 2012-10-19 Shachar Shayovitz , Dan Raphaeli

Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 R. Morelli , L. Clissa , M. Dalla , M. Luppi , L. Rinaldi , A. Zoccoli

We propose a simple yet effective wireless network coding and decoding technique. It utilizes spatial diversity through cooperation between nodes which carry out distributed encoding operations dictated by generator matrices of linear block…

Information Theory · Computer Science 2016-11-17 Tugcan Aktas , Ali Ozgur Yilmaz , Emre Aktas

Millimeter wave (mmWave) and terahertz MIMO systems rely on pre-defined beamforming codebooks for both initial access and data transmission. Being pre-defined, however, these codebooks are commonly not optimized for specific environments,…

Information Theory · Computer Science 2021-02-24 Yu Zhang , Muhammad Alrabeiah , Ahmed Alkhateeb

Magnetic Resonance Fingerprinting (MRF) is an emerging technology with the potential to revolutionize radiology and medical diagnostics. In comparison to traditional magnetic resonance imaging (MRI), MRF enables the rapid, simultaneous,…

Multiple reads of the same Flash memory cell with distinct word-line voltages provide enhanced precision for LDPC decoding. In this paper, the word-line voltages are optimized by maximizing the mutual information (MI) of the quantized…

Information Theory · Computer Science 2014-02-20 Jiadong Wang , Kasra Vakilinia , Tsung-Yi Chen , Thomas Courtade , Guiqiang Dong , Tong Zhang , Hari Shankar , Richard Wesel

Most human protein-coding genes can be transcribed into multiple possible distinct mRNA isoforms. These alternative splicing patterns encourage molecular diversity and dysregulation of isoform expression plays an important role in disease…

Quantitative Methods · Quantitative Biology 2018-05-09 Derek Aguiar , Li-Fang Cheng , Bianca Dumitrascu , Fantine Mordelet , Athma A Pai , Barbara E Engelhardt

The statistical physics properties of low-density parity-check codes for the binary symmetric channel are investigated as a spin glass problem with multi-spin interactions and quenched random fields by the cavity method. By evaluating the…

Statistical Mechanics · Physics 2015-01-20 Haiping Huang

Mitotic activity is a crucial proliferation biomarker for the diagnosis and prognosis of different types of cancers. Nevertheless, mitosis counting is a cumbersome process for pathologists, prone to low reproducibility, due to the large…

Image and Video Processing · Electrical Eng. & Systems 2022-12-01 Claudio Fernandez-Martín , Umay Kiraz , Julio Silva-Rodríguez , Sandra Morales , Emiel Janssen , Valery Naranjo