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In this work, we develop an attention convolutional neural network (CNN) to segment brain tumors from Magnetic Resonance Images (MRI). Further, we predict the survival rate using various machine learning methods. We adopt a 3D UNet…

Image and Video Processing · Electrical Eng. & Systems 2021-04-05 Mobarakol Islam , Vibashan VS , V Jeya Maria Jose , Navodini Wijethilake , Uppal Utkarsh , Hongliang Ren

Accurate classification of brain tumors from magnetic resonance imaging (MRI) plays a critical role in early diagnosis and effective treatment planning. In this study, we propose a deep learning framework based on Vision Transformers (ViT)…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Faisal Ahmed

Purpose: We aimed to develop a data-driven multiomics approach integrating radiomics, dosiomics, and delta features to predict treatment response at an earlier stage (intra-treatment) for brain metastases (BMs) patients treated with PULSAR.…

Highly malignant brain tumors such as Glioblastoma Multiforme (GBM) form complex growth patterns in vitro in which invasive cells organize in tenuous branches. Here, we formulate a chemotaxis model for this sort of growth. A key element…

Biological Physics · Physics 2009-11-07 Leonard M. Sander , Thomas S. Deisboeck

Prediction of survivability in a patient for tumor progression is useful to estimate the effectiveness of a treatment protocol. In our work, we present a model to take into account the heterogeneous nature of a tumor to predict survival.…

Tumour heterogeneity is increasingly recognized as a major obstacle to therapeutic success across neuro-oncology. Gliomas are characterised by distinct combinations of genetic and epigenetic alterations, resulting in complex interactions…

Glioblastoma, a highly aggressive brain tumor, poses major challenges due to its poor prognosis and high morbidity rates. Partial differential equation-based models offer promising potential to enhance therapeutic outcomes by simulating…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Zeineb Haouari , Jonas Weidner , Yeray Martin-Ruisanchez , Ivan Ezhov , Aswathi Varma , Daniel Rueckert , Bjoern Menze , Benedikt Wiestler

Quantitative extraction of high-dimensional mineable data from medical images is a process known as radiomics. Radiomics is foreseen as an essential prognostic tool for cancer risk assessment and the quantification of intratumoural…

Glioma, the malignant brain tumor, requires immediate treatment to improve the survival of patients. Gliomas heterogeneous nature makes the segmentation difficult, especially for sub-regions like necrosis, enhancing tumor, non-enhancing…

Image and Video Processing · Electrical Eng. & Systems 2020-12-01 Rupal Agravat , Mehul S Raval

Background: As an important branch of machine learning pipelines in medical imaging, radiomics faces two major challenges namely reproducibility and accessibility. In this work, we introduce open-radiomics, a set of radiomics datasets along…

Quantitative Methods · Quantitative Biology 2025-03-04 Khashayar Namdar , Matthias W. Wagner , Birgit B. Ertl-Wagner , Farzad Khalvati

In medical imaging, most of the image registration methods implicitly assume a one-to-one correspondence between the source and target images (i.e., diffeomorphism). However, this is not necessarily the case when dealing with pathological…

Image and Video Processing · Electrical Eng. & Systems 2022-02-03 Matthis Maillard , Anton François , Joan Glaunès , Isabelle Bloch , Pietro Gori

Overall survival (OS) time is one of the most important evaluation indices for gliomas situations. Multimodal Magnetic Resonance Imaging (MRI) scans play an important role in the study of glioma prognosis OS time. Several deep…

Image and Video Processing · Electrical Eng. & Systems 2024-04-19 Wen Tang , Haoyue Zhang , Pengxin Yu , Han Kang , Rongguo Zhang

Brain tumors are among the deadliest diseases in the world. Magnetic Resonance Imaging (MRI) is one of the most effective ways to detect brain tumors. Accurate detection of brain tumors based on MRI scans is critical, as it can potentially…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Xiaoyi Liu , Zhuoyue Wang

Multimodal machine learning integrating histopathology and molecular data shows promise for cancer prognostication. We systematically reviewed studies combining whole slide images (WSIs) and high-throughput omics to predict overall…

Quantitative Methods · Quantitative Biology 2025-07-30 Charlotte Jennings , Andrew Broad , Lucy Godson , Emily Clarke , David Westhead , Darren Treanor

Gliomas are brain tumors composed of different highly heterogeneous histological subregions. Image analysis techniques to identify relevant tumor substructures have high potential for improving patient diagnosis, treatment and prognosis.…

Image and Video Processing · Electrical Eng. & Systems 2022-07-18 José Gerardo Suárez-García Javier Miguel Hernández-López , Eduardo Moreno-Barbosa , Benito de Celis-Alonso

Brain tumor is a life-threatening problem and hampers the normal functioning of the human body. The average five-year relative survival rate for malignant brain tumors is 35.6 percent. For proper diagnosis and efficient treatment planning,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-16 Vidhyapriya Ranganathan , Celshiya Udaiyar , Jaisree Jayanth , Meghaa P , Srija B , Uthra S

Glioblastoma recurrence is largely driven by diffuse infiltration beyond radiologically visible tumor margins, yet standard radiotherapy, the mainstay of glioblastoma treatment, relies on uniform expansions that ignore patient-specific…

Image and Video Processing · Electrical Eng. & Systems 2026-03-17 L. Zimmer , J. Weidner , M. Balcerak , F. Kofler , M. Krupa , I. Ezhov , S. Cepeda , R. Zhang , J. Lowengrub , B. Menze , B. Wiestler

We utilize 3-D fully convolutional neural networks (CNN) to segment gliomas and its constituents from multimodal Magnetic Resonance Images (MRI). The architecture uses dense connectivity patterns to reduce the number of weights and residual…

Image and Video Processing · Electrical Eng. & Systems 2021-01-06 Vikas Kumar Anand , Sanjeev Grampurohit , Pranav Aurangabadkar , Avinash Kori , Mahendra Khened , Raghavendra S Bhat , Ganapathy Krishnamurthi

In this work, we study the in-vitro dynamics of the most malignant form of the primary brain tumor: Glioblastoma Multiforme. Typically, the growing tumor consists of the inner dense proliferating zone and the outer less dense invasive…

Cell Behavior · Quantitative Biology 2009-11-11 Evgeniy Khain , Leonard M. Sander

Glioblastoma is among the most aggressive brain tumors in adults, characterized by patient-specific invasion patterns driven by the underlying brain microstructure. In this work, we present a proof-of-concept for a mathematical model of GBL…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 D. Cerrone , D. Riccobelli , S. Gazzoni , P. Vitullo , F. Ballarin , J. Falco , F. Acerbi , A. Manzoni , P. Zunino , P. Ciarletta
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