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Surgery planning in patients diagnosed with brain tumor is dependent on their survival prognosis. A poor prognosis might demand for a more aggressive treatment and therapy plan, while a favorable prognosis might enable a less risky surgery…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 Sobia Yousaf , Syed Muhammad Anwar , Harish RaviPrakash , Ulas Bagci

Survival prediction models can potentially be used to guide treatment of glioblastoma patients. However, currently available MR imaging biomarkers holding prognostic information are often challenging to interpret, have difficulties…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Sveinn Pálsson , Stefano Cerri , Hans Skovgaard Poulsen , Thomas Urup , Ian Law , Koen Van Leemput

Purpose: To develop a novel deep-learning model that integrates radiomics analysis in a multi-dimensional feature fusion workflow for glioblastoma (GBM) post-resection survival prediction. Methods: A cohort of 235 GBM patients with complete…

Medical Physics · Physics 2022-03-14 Zongsheng Hu , Zhenyu Yang , Haozhao Zhang , Eugene Vaios , Kyle Lafata , Fang-Fang Yin , Chunhao Wang

Gliomas are the most common malignant brain tumourswith intrinsic heterogeneity. Accurate segmentation of gliomas and theirsub-regions on multi-parametric magnetic resonance images (mpMRI)is of great clinical importance, which defines…

Image and Video Processing · Electrical Eng. & Systems 2019-11-21 Shuo Wang , Chengliang Dai , Yuanhan Mo , Elsa Angelini , Yike Guo , Wenjia Bai

The accurate prognosis of Glioblastoma Multiforme (GBM) plays an essential role in planning correlated surgeries and treatments. The conventional models of survival prediction rely on radiomic features using magnetic resonance imaging…

Image and Video Processing · Electrical Eng. & Systems 2021-05-03 Mobarakol Islam , Navodini Wijethilake , Hongliang Ren

We propose predictive models that estimate GBM patients' health status of one-year after treatments (Classification task), predict the long-term prognosis of GBM patients at an individual level (Survival task). We used total of 467 GBM…

Machine Learning · Computer Science 2021-09-10 Yeseul Kim , Kyung Hwan Kim , Junyoung Park , Hong In Yoon , Wonmo Sung

Glioblastoma is one of the most aggressive and common brain tumors, with a median survival of 10-15 months. Predicting Overall Survival (OS) is critical for personalizing treatment strategies and aligning clinical decisions with patient…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Yin Lin , Riccardo Barbieri , Domenico Aquino , Giuseppe Lauria , Marina Grisoli , Elena De Momi , Alberto Redaelli , Simona Ferrante

This paper proposes to use deep radiomic features (DRFs) from a convolutional neural network (CNN) to model fine-grained texture signatures in the radiomic analysis of recurrent glioblastoma (rGBM). We use DRFs to predict survival of rGBM…

Computer Vision and Pattern Recognition · Computer Science 2019-11-18 Ahmad Chaddad , Saima Rathore , Mingli Zhang , Christian Desrosiers , Tamim Niazi

GBM (Glioblastoma multiforme) is the most aggressive type of brain tumor in adults that has a short survival rate even after aggressive treatment with surgery and radiation therapy. The changes on magnetic resonance imaging (MRI) for…

Image and Video Processing · Electrical Eng. & Systems 2023-06-07 M. S. Sadique , W. Farzana , A. Temtam , E. Lappinen , A. Vossough , K. M. Iftekharuddin

Currently, there is a noticeable lack of AI in the medical field to support doctors in treating heterogenous brain tumors such as Glioblastoma Multiforme (GBM), the deadliest human cancer in the world with a five-year survival rate of just…

Artificial Intelligence · Computer Science 2025-12-09 Krishna Arun , Moinak Bhattachrya , Paras Goel

Gliomas are among the most aggressive cancers, characterized by high mortality rates and complex diagnostic processes. Existing studies on glioma diagnosis and classification often describe issues such as high variability in imaging data,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Md. Abdur Rahman , Mohaimenul Azam Khan Raiaan , Arefin Ittesafun Abian , Yan Zhang , Mirjam Jonkman , Sami Azam

In this paper we propose a method for predicting the status of MGMT promoter methylation in high-grade gliomas. From the available MR images, we segment the tumor using deep convolutional neural networks and extract both radiomic features…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Sveinn Pálsson , Stefano Cerri , Koen Van Leemput

Glioblastoma, a highly aggressive brain tumor with diverse molecular and pathological features, poses a diagnostic challenge due to its heterogeneity. Accurate diagnosis and assessment of this heterogeneity are essential for choosing the…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Juexin Zhang , Ying Weng , Ke Chen

Glioblastoma is the most common primary adult brain tumor, with a grim prognosis - median survival of 12-18 months following treatment, and 4 months otherwise. Glioblastoma is widely infiltrative in the cerebral hemispheres and well-defined…

Objectives: Glioblastomas are the most aggressive brain and central nervous system (CNS) tumors with poor prognosis in adults. The purpose of this study is to develop a machine-learning based classification method using radio-mic features…

Medical Physics · Physics 2019-11-25 Ge Cui , Jiwoong Jeong , Bob Press , Yang Lei , Hui-Kuo Shu , Tian Liu , Walter Curran , Hui Mao , Xiaofeng Yang

Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

Machine Learning · Computer Science 2022-07-20 Can Cui , Han Liu , Quan Liu , Ruining Deng , Zuhayr Asad , Yaohong WangShilin Zhao , Haichun Yang , Bennett A. Landman , Yuankai Huo

We propose a curve-based Riemannian-geometric approach for general shape-based statistical analyses of tumors obtained from radiologic images. A key component of the framework is a suitable metric that (1) enables comparisons of tumor…

Applications · Statistics 2017-02-07 Karthik Bharath , Sebastian Kurtek , Arvind Rao , Veerabhadran Baladandayuthapani

Glioblastoma is the most malignant type of central nervous system tumor with GBM subtypes cleaved based on molecular level gene alterations. These alterations are also happened to affect the histology. Thus, it can cause visible changes in…

Quantitative Methods · Quantitative Biology 2020-10-28 Navodini Wijethilake , Mobarakol Islam , Dulani Meedeniya , Charith Chitraranjan , Indika Perera , Hongliang Ren

Glioblastoma is one of the most aggressive and deadliest types of brain cancer, with low survival rates compared to other types of cancer. Analysis of Magnetic Resonance Imaging (MRI) scans is one of the most effective methods for the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Huafeng Liu , Benjamin Dowdell , Todd Engelder , Zarah Pulmano , Nicolas Osa , Arko Barman

Glioblastoma Multiforme is a high grade, very aggressive, brain tumor, with patients having a poor prognosis. Lower grade gliomas are less aggressive, but they can evolve into higher grade tumors over time. Patient management and treatment…

Computer Vision and Pattern Recognition · Computer Science 2018-11-01 Sergio Pereira , Raphael Meier , Victor Alves , Mauricio Reyes , Carlos A. Silva
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