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The transmission dynamics of an epidemic are rarely homogeneous. Super-spreading events and super-spreading individuals are two types of heterogeneous transmissibility. Inference of super-spreading is commonly carried out on secondary case…

Quantitative Methods · Quantitative Biology 2025-01-23 Hannah Craddock , Simon EF Spencer , Xavier Didelot

Susceptible-Exposed-Infectious-Recovered (SEIR) models with inter-individual variation in susceptibility or exposure to infection were proposed early in the COVID-19 pandemic as a potential element of the mathematical/statistical toolset…

Applications · Statistics 2025-10-28 Ibrahim Mohammed , Chris Robertson , M. Gabriela M. Gomes

Epidemiological models are best suitable to model an epidemic if the spread pattern is stationary. To deal with non-stationary patterns and multiple waves of an epidemic, we develop a hybrid model encompassing epidemic modeling, particle…

Machine Learning · Computer Science 2024-02-01 Naresh Kumar , Seba Susan

In Federated Learning, heterogeneity in client data distributions often means that a single global model does not have the best performance for individual clients. Consider for example training a next-word prediction model for keyboards:…

Machine Learning · Computer Science 2025-05-06 Ljubomir Rokvic , Panayiotis Danassis , Boi Faltings

Despite advances in language modelling, distributional methods that build semantic representations from co-occurrences fail to discriminate between plausible and implausible events. In this work, we investigate how plausibility prediction…

Computation and Language · Computer Science 2025-03-18 Jacob Chmura , Jonah Dauvet , Sebastian Sabry

Accurate and representative data is vital for precisely reporting the impact of influenza in healthcare systems. Northern hemisphere winter 2022/23 experienced the most substantial influenza wave since the COVID-19 pandemic began in 2020.…

Populations and Evolution · Quantitative Biology 2023-10-26 Jonathon Mellor , Rachel Christie , James Guilder , Robert S Paton , Suzanne Elgohari , Conall Watson , Sarah Deeny , Thomas Ward

Influenza-like illness (ILI) estimation from web search data is an important web analytics task. The basic idea is to use the frequencies of queries in web search logs that are correlated with past ILI activity as features when estimating…

Information Retrieval · Computer Science 2018-02-21 Niels Dalum Hansen , Kåre Mølbak , Ingemar J. Cox , Christina Lioma

Individual-based models of contagious processes are useful for predicting epidemic trajectories and informing intervention strategies. In such models, the incorporation of contact network information can capture the non-randomness and…

Populations and Evolution · Quantitative Biology 2023-11-09 Maxwell H. Wang , Jukka-Pekka Onnela

Epidemic forecasting faces a fundamental challenge: human behavior dynamically responds to disease spread, creating feedback loops that induce distribution shifts at policy intervention points. This renders data-driven models unreliable…

Machine Learning · Computer Science 2026-05-27 Haochun Wang , Sendong Zhao , Jingbo Wang , Yanrui Du , Bing Qin , Ting Liu

In two previous papers, I introduced SuperSpreader (SS) epidemic models, offered some theoretical discussion of prevention issues, and fitted some models to data derived from published accounts of the ongoing MERS epidemic (concluding that…

Populations and Evolution · Quantitative Biology 2014-06-24 W. David Wick

The accurate estimation of time-varying transmission rates is fundamental for understanding infectious disease dynamics and implementing effective public health interventions. To this end, we propose an improved inverse method for…

Populations and Evolution · Quantitative Biology 2025-12-17 Shuanglin Jing , Yuting Huang , Hai-Feng Huo

An information-theoretic framework is developed to assess the predictability of ENSO complexity, which is a central problem in contemporary meteorology with large societal impacts. The information theory advances a unique way to quantify…

Atmospheric and Oceanic Physics · Physics 2023-04-05 Xianghui Fang , Nan Chen

Integrating data from multiple heterogeneous sources has become increasingly popular to achieve a large sample size and diverse study population. This paper reviews development in causal inference methods that combines multiple datasets…

Methodology · Statistics 2021-10-05 Xu Shi , Ziyang Pan , Wang Miao

Large Language Models (LLMs) are susceptible to security and safety threats, such as prompt injection, prompt extraction, and harmful requests. One major cause of these vulnerabilities is the lack of an instruction hierarchy. Modern LLM…

The mathematical interpretation of interventions for the mitigation of epidemics and pandemics in the literature often involves finding the optimal time to initiate an intervention and/or the use of infections to manage impact. Whilst these…

Populations and Evolution · Quantitative Biology 2023-05-17 James Van Yperen , Eduard Campillo-Funollet , Rebecca Inkpen , Anjum Memon , Anotida Madzvamuse

The features in high dimensional biomedical prediction problems are often well described with lower dimensional manifolds. An example is genes that are organised in smaller functional networks. The outcome can then be described with the…

Future Event Prediction (FEP) is an essential activity whose demand and application range across multiple domains. While traditional methods like simulations, predictive and time-series forecasting have demonstrated promising outcomes,…

Machine Learning · Computer Science 2025-02-13 Anisha Saha , Adam Jatowt

Modelling epidemics via classical population-based models suffers from shortcomings that so-called individual-based models are able to overcome, as they are able to take heterogeneity features into account, such as super-spreaders, and…

Optimization and Control · Mathematics 2022-05-16 C. Courtès , E. Franck , K. Lutz , L. Navoret , Y. Privat

Severe acute respiratory disease SARS-CoV-2 has had a found impact on public health systems and healthcare emergency response especially with respect to making decisions on the most effective measures to be taken at any given time. As…

Machine Learning · Computer Science 2023-09-19 Charithea Stylianides , Kleanthis Malialis , Panayiotis Kolios

Forecasts of hospitalisations of infectious diseases play an important role for allocating healthcare resources during epidemics and pandemics. Large-scale analysis of model forecasts during the COVID-19 pandemic has shown that the model…

Populations and Evolution · Quantitative Biology 2025-05-20 Grégoire Béchade , Torbjörn Lundh , Philip Gerlee