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Drug discovery remains a slow and expensive process that involves many steps, from detecting the target structure to obtaining approval from the Food and Drug Administration (FDA), and is often riddled with safety concerns. Accurate…

Quantitative Methods · Quantitative Biology 2025-08-22 Ali Vefghi , Zahed Rahmati , Mohammad Akbari

Artificial Intelligence (AI) is being adopted across the world and promises a new revolution in healthcare. While AI-enabled medical devices in North America dominate 42.3% of the global market, the use of AI-enabled medical devices in…

Computers and Society · Computer Science 2024-06-14 Attrayee Chakraborty , Mandar Karhade

Deep learning applications have been thriving over the last decade in many different domains, including computer vision and natural language understanding. The drivers for the vibrant development of deep learning have been the availability…

Signal Processing · Electrical Eng. & Systems 2020-05-06 Olga Fink , Qin Wang , Markus Svensén , Pierre Dersin , Wan-Jui Lee , Melanie Ducoffe

Machine learning is employed in healthcare to draw approximate conclusions regarding human diseases and mental health problems. Compared to older traditional methods, it can help to analyze data more efficiently and produce better and more…

Neurons and Cognition · Quantitative Biology 2023-05-25 Narges Ramesh , Yasmin Ghodsi , Hamidreza Bolhasani

In recent decades, traditional drug research and development have been facing challenges such as high cost, long timelines, and high risks. To address these issues, many computational approaches have been suggested for predicting the…

Quantitative Methods · Quantitative Biology 2023-09-13 Chunyan Ao , Zhichao Xiao , Lixin Guan , Liang Yu

The combination of Reinforcement Learning (RL) with deep learning has led to a series of impressive feats, with many believing (deep) RL provides a path towards generally capable agents. However, the success of RL agents is often highly…

The integration of artificial intelligence (AI) into mobile applications has significantly transformed various domains, enhancing user experiences and providing personalized services through advanced machine learning (ML) and deep learning…

Software Engineering · Computer Science 2024-09-30 Yinghua Li , Xueqi Dang , Haoye Tian , Tiezhu Sun , Zhijie Wang , Lei Ma , Jacques Klein , Tegawendé F. Bissyandé

Artificial intelligence (AI) is expected to revolutionize the practice of medicine. Recent advancements in the field of deep learning have demonstrated success in a variety of clinical tasks: detecting diabetic retinopathy from images,…

Machine Learning · Computer Science 2025-04-04 Joshua Hatherley

Drug promiscuity and polypharmacology are much discussed topics in pharmaceutical research. Drug repositioning applies established drugs to new disease indications with increasing success. As polypharmacology, defined a drug's ability to…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-05-16 Antonios Makris

Hit identification is a central challenge in early drug discovery, traditionally requiring substantial experimental resources. Recent advances in artificial intelligence, particularly large language models (LLMs), have enabled virtual…

The integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing…

Quantitative Methods · Quantitative Biology 2024-09-10 Yizhen Zheng , Huan Yee Koh , Maddie Yang , Li Li , Lauren T. May , Geoffrey I. Webb , Shirui Pan , George Church

The advent of Artificial intelligence has promising advantages that can be utilized to transform the landscape of software project development. The Software process framework consists of activities that constantly require routine human…

Software Engineering · Computer Science 2024-09-02 Mariyam Mahboob , Mohammed Rayyan Uddin Ahmed , Zoiba Zia , Mariam Shakeel Ali , Ayman Khaleel Ahmed

Drug-drug interaction (DDI) is a vital information when physicians and pharmacists intend to co-administer two or more drugs. Thus, several DDI databases are constructed to avoid mistakenly combined use. In recent years, automatically…

Computation and Language · Computer Science 2017-05-19 Zibo Yi , Shasha Li , Jie Yu , Qingbo Wu

The discussions around Artificial Intelligence (AI) and medical imaging are centered around the success of deep learning algorithms. As new algorithms enter the market, it is important for practicing radiologists to understand the pitfalls…

Image and Video Processing · Electrical Eng. & Systems 2022-11-28 Rishi Gadepally , Andrew Gomella , Eric Gingold , Paras Lakhani

Remarkable success of modern image-based AI methods and the resulting interest in their applications in critical decision-making processes has led to a surge in efforts to make such intelligent systems transparent and explainable. The need…

Artificial Intelligence · Computer Science 2020-11-30 Adriano Lucieri , Muhammad Naseer Bajwa , Andreas Dengel , Sheraz Ahmed

Machine Learning (ML) is increasingly being adopted in different industries. Deep Reinforcement Learning (DRL) is a subdomain of ML used to produce intelligent agents. Despite recent developments in DRL technology, the main challenges that…

Software Engineering · Computer Science 2024-05-21 Mohammad Mehdi Morovati , Florian Tambon , Mina Taraghi , Amin Nikanjam , Foutse Khomh

Machine learning plays a role in many aspects of modern IR systems, and deep learning is applied in all of them. The fast pace of modern-day research has given rise to many different approaches for many different IR problems. The amount of…

Information Retrieval · Computer Science 2017-07-14 Tom Kenter , Alexey Borisov , Christophe Van Gysel , Mostafa Dehghani , Maarten de Rijke , Bhaskar Mitra

Deep Learning (DL) has become a crucial technology for Artificial Intelligence (AI). It is a powerful technique to automatically extract high-level features from complex data which can be exploited for applications such as computer vision,…

Computer Vision and Pattern Recognition · Computer Science 2019-06-10 Gael Kamdem De Teyou

Artificial intelligence (AI), machine learning, and deep learning have become transformative forces in big data analytics and management, enabling groundbreaking advancements across diverse industries. This article delves into the…

Opioid use disorder (OUD) is a chronic and relapsing condition that involves the continued and compulsive use of opioids despite harmful consequences. The development of medications with improved efficacy and safety profiles for OUD…

Biomolecules · Quantitative Biology 2023-03-02 Hongsong Feng , Jian Jiang , Guo-Wei Wei
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