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Photoacoustic computed tomography (PACT) is an emerging computed imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the absorbed optical energy density within tissue. When the imaging…
Colorectal cancer is a deadly disease that has become increasingly prevalent in recent years. Early detection is crucial for saving lives, but traditional diagnostic methods such as colonoscopy and biopsy have limitations. Colonoscopy…
We revisit the controversial "abscopal" effect in the context of Personalized Ultra-Fractionated Stereotactic Adaptive Radiotherapy (PULSAR). By allowing long interval between fractions, PULSAR may enhance systemic immune activation and…
Detection and identification of lipids are highly coveted for the interrogation of chronic diseases such as atherosclerosis and myocardial infarction. Intravascular photoacoustic imaging (IVPA) and deep tissue imaging are modern techniques,…
Biological signaling is imagined as a combination of activation and transport. The former is triggered by local molecular interactions and the latter is the result of molecular diffusion. However, other fundamental physical principles of…
This paper is devoted to the study of photothermal transformations in multilayered structures. As a modelled sample, porous silicon with a periodic distribution of the porosity was chosen. The spatial distribution of the optical properties…
High-harmonic generation is one of the most extreme nonlinear-optical processes observed to date. By focusing an intense laser pulse into a gas, the light-atom interaction that occurs during the process of ionising the atoms results in the…
Currently, free flaps and pedicled flaps are assessed for reperfusion in post-operative care using colour, capillary refill, temperature, texture and Doppler signal (if available). While these techniques are effective, they are prone to…
A crucial limitation of current high-resolution 3D photoacoustic tomography (PAT) devices that employ sequential scanning is their long acquisition time. In previous work, we demonstrated how to use compressed sensing techniques to improve…
Intracellular structural alterations are hallmark of several disease conditions and treatment modalities. However, robust methods to quantify these changes are scarce. In view of this, we introduce a new method to quantify structural…
Volumetric, multimodal imaging with precise spatial and temporal co-registration can provide valuable and complementary information for diagnosis and monitoring. Considerable research has sought to combine 3D photoacoustic (PA) and…
Photoacoustic (PA) imaging technology combines the advantages of optical imaging and ultrasound imaging, showing great potential in biomedical applications. Many preclinical studies and clinical applications urgently require fast,…
Ultrafast measurement technology provides essential contributions to our microscopic understanding of the properties and functions of solids and nanostructures. Atomic-scale vistas with ever-growing spatial and temporal resolution are…
In an inhomogeneously illuminated photoacoustic image, important information like vascular geometry is not readily available when only the initial pressure is reconstructed. To obtain the desired information, algorithms for image…
Medical image fusion is the process of registering and combining multiple images from single or multiple imaging modalities to improve the imaging quality and reduce randomness and redundancy in order to increase the clinical applicability…
Achieving effective synergy between radiotherapy and immunotherapy is critical for optimizing tumor control and treatment outcomes. To explore the underlying mechanisms of this synergy, we have investigated a novel treatment approach known…
Artificial intelligence represents a new frontier in human medicine that could save more lives and reduce the costs, thereby increasing accessibility. As a consequence, the rate of advancement of AI in cancer medical imaging and more…
Photoacoustic computed tomography (PACT) is a proven technology for imaging hemodynamics in deep brain of small animal models. PACT is inherently compatible with ultrasound (US) imaging, providing complementary contrast mechanisms. While…
Recent advances in cancer research largely rely on new developments in microscopic or molecular profiling techniques offering high level of detail with respect to either spatial or molecular features, but usually not both. Here, we present…
Ultrasound is an adjunct tool to mammography that can quickly and safely aid physicians with diagnosing breast abnormalities. Clinical ultrasound often assumes a constant sound speed to form B-mode images for diagnosis. However, the various…