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With the growing utilization of machine learning in healthcare, there is increasing potential to enhance healthcare outcomes. However, this also brings the risk of perpetuating biases in data and model design that can harm certain…

Machine Learning · Computer Science 2023-08-15 Shaina Raza , Parisa Osivand Pour , Syed Raza Bashir

The use of machine learning to guide clinical decision making has the potential to worsen existing health disparities. Several recent works frame the problem as that of algorithmic fairness, a framework that has attracted considerable…

Machine Learning · Statistics 2021-06-16 Stephen R. Pfohl , Agata Foryciarz , Nigam H. Shah

Machine learning (ML) promises to revolutionize public health through improved surveillance, risk stratification, and resource allocation. However, without systematic attention to algorithmic bias, ML may inadvertently reinforce existing…

Artificial Intelligence · Computer Science 2025-10-17 Sara Altamirano , Arjan Vreeken , Sennay Ghebreab

Machine learning (ML) in medicine has transitioned from research to concrete applications aimed at supporting several medical purposes like therapy selection, monitoring and treatment. Acceptance and effective adoption by clinicians and…

Autonomous vehicles rely on machine learning to solve challenging tasks in perception and motion planning. However, automotive software safety standards have not fully evolved to address the challenges of machine learning safety such as…

Machine Learning · Computer Science 2019-12-23 Sina Mohseni , Mandar Pitale , Vasu Singh , Zhangyang Wang

Increasingly sophisticated mathematical modelling processes from Machine Learning are being used to analyse complex data. However, the performance and explainability of these models within practical critical systems requires a rigorous and…

Machine Learning · Computer Science 2020-12-08 Xingyu Zhao , Alec Banks , James Sharp , Valentin Robu , David Flynn , Michael Fisher , Xiaowei Huang

Artificial Intelligence (AI) systems are now an integral part of multiple industries. In clinical research, AI supports automated adverse event detection in clinical trials, patient eligibility screening for protocol enrollment, and data…

Artificial Intelligence · Computer Science 2025-12-10 Laxmiraju Kandikatla , Branislav Radeljic

The open-world deployment of Machine Learning (ML) algorithms in safety-critical applications such as autonomous vehicles needs to address a variety of ML vulnerabilities such as interpretability, verifiability, and performance limitations.…

Machine Learning · Computer Science 2022-03-09 Sina Mohseni , Haotao Wang , Zhiding Yu , Chaowei Xiao , Zhangyang Wang , Jay Yadawa

Recently, deep learning has been successfully applied to a variety of networking problems. A fundamental challenge is that when the operational environment for a learning-augmented system differs from its training environment, such systems…

Machine Learning · Computer Science 2020-10-09 Noga H. Rotman , Michael Schapira , Aviv Tamar

While the applications and demands of Machine learning (ML) systems in mental health are growing, there is little discussion nor consensus regarding a uniquely challenging aspect: building security methods and requirements into these ML…

Computers and Society · Computer Science 2020-08-19 Helen Jiang , Erwen Senge

While artificial-intelligence-based methods suffer from lack of transparency, rule-based methods dominate in safety-critical systems. Yet, the latter cannot compete with the first ones in robustness to multiple requirements, for instance,…

Artificial Intelligence · Computer Science 2022-02-01 Andrei Aksjonov , Ville Kyrki

Heart disease is one of the significant challenges in today's world and one of the leading causes of many deaths worldwide. Recent advancement of machine learning (ML) application demonstrates that using electrocardiogram (ECG) and patient…

Machine Learning · Computer Science 2021-12-14 Md Manjurul Ahsan , Zahed Siddique

Multiple organ failure (MOF) is a life-threatening condition. Due to its urgency and high mortality rate, early detection is critical for clinicians to provide appropriate treatment. In this paper, we perform quantitative analysis on early…

Machine Learning · Computer Science 2021-04-26 Yuqing Wang , Yun Zhao , Rachael Callcut , Linda Petzold

Medicare fraud poses a substantial challenge to healthcare systems, resulting in significant financial losses and undermining the quality of care provided to legitimate beneficiaries. This study investigates the use of machine learning (ML)…

Machine Learning · Computer Science 2025-02-25 Dorsa Farahmandazad , Kasra Danesh

Cardiovascular disease remains a leading global cause of mortality, necessitating accurate risk prediction tools. Traditional methods, such as QRISK and the Framingham heart score, exhibit limitations in their ability to incorporate…

Genomics · Quantitative Biology 2024-02-12 Farnoush Shishehbori , Zainab Awan

Current pharmaceutical formulation development still strongly relies on the traditional trial-and-error approach by individual experiences of pharmaceutical scientists, which is laborious, time-consuming and costly. Recently, deep learning…

Machine Learning · Computer Science 2018-12-05 Yilong Yang , Zhuyifan Ye , Yan Su , Qianqian Zhao , Xiaoshan Li , Defang Ouyang

The adoption of machine learning (ML) and, more specifically, deep learning (DL) applications into all major areas of our lives is underway. The development of trustworthy AI is especially important in medicine due to the large implications…

Machine Learning · Computer Science 2024-02-22 Daniel Schwabe , Katinka Becker , Martin Seyferth , Andreas Klaß , Tobias Schäffter

This paper considers the use of Machine Learning (ML) in medicine by focusing on the main problem that this computational approach has been aimed at solving or at least minimizing: uncertainty. To this aim, we point out how uncertainty is…

Machine Learning · Computer Science 2018-05-15 Federico Cabitza , Davide Ciucci , Raffaele Rasoini

This paper proposes a framework based on a causal model of safety upon which effective safety assurance cases for ML-based applications can be built. In doing so, we build upon established principles of safety engineering as well as…

Software Engineering · Computer Science 2022-08-10 Simon Burton

Medical datasets are typically affected by issues such as missing values, class imbalance, a heterogeneous feature types, and a high number of features versus a relatively small number of samples, preventing machine learning models from…