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Trust is a crucial factor affecting the adoption of machine learning (ML) models. Qualitative studies have revealed that end-users, particularly in the medical domain, need models that can express their uncertainty in decision-making…

Machine Learning · Computer Science 2023-04-21 Andrew Houston , Georgina Cosma

Human decision-making differs due to variation in both incentives and available information. This constitutes a substantial challenge for the evaluation of whether and how machine learning predictions can improve decision outcomes. We…

General Economics · Economics 2020-11-24 Michael Allan Ribers , Hannes Ullrich

Identifying potential social and ethical risks in emerging machine learning (ML) models and their applications remains challenging. In this work, we applied two well-established safety engineering frameworks (FMEA, STPA) to a case study…

Computers and Society · Computer Science 2023-07-21 Shalaleh Rismani , Renee Shelby , Andrew Smart , Renelito Delos Santos , AJung Moon , Negar Rostamzadeh

Machine learning has evolved into an enabling technology for a wide range of highly successful applications. The potential for this success to continue and accelerate has placed machine learning (ML) at the top of research, economic and…

Machine Learning · Computer Science 2019-05-13 Rob Ashmore , Radu Calinescu , Colin Paterson

The lack of transparency and explainability hinders the clinical adoption of Machine learning (ML) algorithms. While explainable artificial intelligence (XAI) methods have been proposed, little research has focused on the agreement between…

Machine Learning · Computer Science 2023-11-29 Aida Brankovic , Wenjie Huang , David Cook , Sankalp Khanna , Konstanty Bialkowski

This paper reviews the reasons that Human-in-the-Loop is both critical for preventing widely-understood failure modes for machine learning, and not a practical solution. Following this, we review two current heuristic methods for addressing…

Artificial Intelligence · Computer Science 2018-11-26 David Manheim

This paper introduces the OPIAID algorithm, a novel approach for predicting and recommending personalized opioid dosages for individual patients. The algorithm optimizes pain management while minimizing opioid related adverse events (ORADE)…

The adoption of machine-learning-enabled systems in the healthcare domain is on the rise. While the use of ML in healthcare has several benefits, it also expands the threat surface of medical systems. We show that the use of ML in medical…

Cryptography and Security · Computer Science 2024-04-15 Mohammed Elnawawy , Mohammadreza Hallajiyan , Gargi Mitra , Shahrear Iqbal , Karthik Pattabiraman

Stroke remains one of the most critical global health challenges, ranking as the second leading cause of death and the third leading cause of disability worldwide. This study explores the effectiveness of machine learning algorithms in…

Machine Learning · Computer Science 2025-05-16 Anastasija Tashkova , Stefan Eftimov , Bojan Ristov , Slobodan Kalajdziski

Artificial intelligence (AI) holds great promise for supporting clinical trials, from patient recruitment and endpoint assessment to treatment response prediction. However, deploying AI without safeguards poses significant risks,…

Machine Learning · Computer Science 2025-10-09 Yao Chen , David Ohlssen , Aimee Readie , Gregory Ligozio , Ruvie Martin , Thibaud Coroller

Machine learning (ML) is widely used in drug discovery to train models that predict protein-ligand binding. These models are of great value to medicinal chemists, in particular if they provide case-specific insight into the physical…

Biomolecules · Quantitative Biology 2022-04-14 Carl Poelking , Gianni Chessari , Christopher W. Murray , Richard J. Hall , Lucy Colwell , Marcel Verdonk

With the universal adoption of machine learning in healthcare, the potential for the automation of societal biases to further exacerbate health disparities poses a significant risk. We explore algorithmic fairness from the perspective of…

Machine Learning · Computer Science 2024-04-02 Md Rahat Shahriar Zawad , Peter Washington

Coronary Artery Disease (CAD) remains a leading cause of morbidity and mortality worldwide. Early detection is critical to recover patient outcomes and decrease healthcare costs. In recent years, machine learning (ML) advancements have…

Artificial Intelligence · Computer Science 2026-03-10 Karan Kumar Singh , Nikita Gajbhiye , Gouri Sankar Mishra

Large language models (LLMs) offer a valuable technology for various applications in healthcare. However, their tendency to hallucinate and the existing reliance on proprietary systems pose challenges in environments concerning critical…

Computation and Language · Computer Science 2025-02-27 Joshua Strong , Qianhui Men , Alison Noble

Machine learning (ML) holds great promise for improving healthcare, but it is critical to ensure that its use will not propagate or amplify health disparities. An important step is to characterize the (un)fairness of ML models - their…

Machine Learning · Computer Science 2023-08-09 Alexander Brown , Nenad Tomasev , Jan Freyberg , Yuan Liu , Alan Karthikesalingam , Jessica Schrouff

In the present medical services, the board, clinical well-being records are as electronic clinical record (EHR/EMR) frameworks. These frameworks store patients' clinical histories in a computerized design. Notwithstanding, a patient's…

Computers and Society · Computer Science 2023-05-19 Shruthi K , Poornima A. S

Ensuring safety and explainability of machine learning (ML) is a topic of increasing relevance as data-driven applications venture into safety-critical application domains, traditionally committed to high safety standards that are not…

Machine Learning · Computer Science 2020-05-28 Koorosh Aslansefat , Ioannis Sorokos , Declan Whiting , Ramin Tavakoli Kolagari , Yiannis Papadopoulos

This paper addresses the current lack of a unified formal framework in machine learning theory, as well as the absence of robust theoretical foundations for interpretability and ethical safety assurance. We first construct a formal…

Logic in Computer Science · Computer Science 2025-11-11 Jianfeng Xu

Causal machine learning (CML) has experienced increasing popularity in healthcare. Beyond the inherent capabilities of adding domain knowledge into learning systems, CML provides a complete toolset for investigating how a system would react…

Machine Learning · Computer Science 2022-06-01 Pedro Sanchez , Jeremy P. Voisey , Tian Xia , Hannah I. Watson , Alison Q. ONeil , Sotirios A. Tsaftaris

This is an article or technical note which is intended to provides an insight journey of Machine Learning Systems (MLS) testing, its evolution, current paradigm and future work. Machine Learning Models, used in critical applications such as…

Software Engineering · Computer Science 2021-02-23 Raju
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