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Related papers: EXMA: A Genomics Accelerator for Exact-Matching

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Motivation: Seed location filtering is critical in DNA read mapping, a process where billions of DNA fragments (reads) sampled from a donor are mapped onto a reference genome to identify genomic variants of the donor. State-of-the-art read…

Similarity search is a fundamental operation for analyzing data series (DS), which are ordered sequences of real values. To enhance efficiency, summarization techniques are employed that reduce the dimensionality of DS. SAX-based approaches…

Databases · Computer Science 2024-12-04 Patrick Schäfer , Jakob Brand , Ulf Leser , Botao Peng , Themis Palpanas

Accurate and reliable Magnetic Resonance Imaging (MRI) analysis is particularly important for adaptive radiotherapy, a recent medical advance capable of improving cancer diagnosis and treatment. Recent studies have shown that IVIM-NET, a…

Hardware Architecture · Computer Science 2024-07-09 Zehuan Zhang , Matej Genci , Hongxiang Fan , Andreas Wetscherek , Wayne Luk

An important linear algebra routine, GEneral Matrix Multiplication (GEMM), is a fundamental operator in deep learning. Compilers need to translate these routines into low-level code optimized for specific hardware. Compiler-level…

Machine Learning · Computer Science 2019-09-25 Huaqing Zhang , Xiaolin Cheng , Hui Zang , Dae Hoon Park

This paper presents a deeply pipelined and massively parallel Binary Search Tree (BST) accelerator for Field Programmable Gate Arrays (FPGAs). Our design relies on the extremely parallel on-chip memory, or Block RAMs (BRAMs) architecture of…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-12-04 Oyku Melikoglu , Oguz Ergin , Behzad Salami , Julian Pavon , Osman Unsal , Adrian Cristal

In the "Big Data" era, a lot of data must be processed and moved between processing and memory units. New technologies and architectures have emerged to improve system performance and overcome the memory bottleneck. The memristor is a…

Hardware Architecture · Computer Science 2026-02-26 Seyed Erfan Fatemieh , Samane Asgari , Mohammad Reza Reshadinezhad

AI models are increasing in size and recent advancement in the community has shown that unlike HPC applications where double precision datatype are required, lower-precision datatypes such as fp8 or int4 are sufficient to bring the same…

Performance · Computer Science 2023-10-11 Saeed Maleki

Exact string matching has been a fundamental problem in computer science for decades because of many practical applications. Some are related to common procedures, such as searching in files and text editors, or, more recently, to more…

Data Structures and Algorithms · Computer Science 2019-07-29 Konstantinos F. Xylogiannopoulos

The utilization of large-scale neural networks on Processing-In-Memory (PIM) accelerators encounters challenges due to constrained on-chip memory capacity. To tackle this issue, current works explore model compression algorithms to reduce…

Hardware Architecture · Computer Science 2024-04-18 Chenyu Wang , Zhen Dong , Daquan Zhou , Zhenhua Zhu , Yu Wang , Jiashi Feng , Kurt Keutzer

Field-programmable gate array (FPGA) based accelerators are being widely used for acceleration of convolutional neural networks (CNNs) due to their potential in improving the performance and reconfigurability for specific application…

Image and Video Processing · Electrical Eng. & Systems 2020-02-04 Martin Ferianc , Hongxiang Fan , Ringo S. W. Chu , Jakub Stano , Wayne Luk

In this project, we have successfully designed, implemented, deployed and tested a novel FPGA accelerated algorithm for neural network training. The algorithm itself was developed in an independent study option. This training method is…

Machine Learning · Computer Science 2020-09-08 Seyedeh Niusha Alavi Foumani , Ce Guo , Wayne Luk

Dedicated hardware accelerators are suitable for parallel computational tasks. Moreover, they have the tendency to accept inexact results. These hardware accelerators are extensively used in image processing and computer vision…

Signal Processing · Electrical Eng. & Systems 2020-01-14 Mahmoud Masadeh , Osman Hasan , Sofiene Tahar

The widespread adoption of mixed-precision quantization in large language models (LLMs) has created demand for hardware that can efficiently perform multiply-accumulate (MAC) operations across mixed datatypes and switch datatypes at…

Hardware Architecture · Computer Science 2026-05-08 Feng Yu , Hongshi Tan , Yao Chen , Weng-Fai Wong , Bingsheng He

Advances in life sciences over the last few decades have lead to the generation of a huge amount of biological data. Computing research has become a vital part in driving biological discovery where analysis and categorization of biological…

Computational Engineering, Finance, and Science · Computer Science 2014-03-31 S. M. Vidanagamachchi , S. D. Dewasurendra , R. G. Ragel , M. Niranjan

DNA sequence alignment involves assigning short DNA reads to the most probable locations on an extensive reference genome. This process is crucial for various genomic analyses, including variant calling, transcriptomics, and epigenomics.…

Accurate protein structure prediction from amino-acid sequences is critical to better understanding the protein function. Recent advances in this area largely benefit from more precise inter-residue distance and orientation predictions,…

Machine Learning · Computer Science 2021-06-01 Jiaxiang Wu , Shitong Luo , Tao Shen , Haidong Lan , Sheng Wang , Junzhou Huang

Subgraph matching has garnered increasing attention for its diverse real-world applications. Given the dynamic nature of real-world graphs, addressing evolving scenarios without incurring prohibitive overheads has been a focus of research.…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-31 Linshan Qiu , Lu Chen , Hailiang Jie , Xiangyu Ke , Yunjun Gao , Yang Liu , Zetao Zhang

Next-generation sequencing (NGS) technologies have enabled affordable sequencing of billions of short DNA fragments at high throughput, paving the way for population-scale genomics. Genomics data analytics at this scale requires overcoming…

Databases · Computer Science 2019-10-11 Darryl Ho , Jialin Ding , Sanchit Misra , Nesime Tatbul , Vikram Nathan , Vasimuddin Md , Tim Kraska

Processing-in-DRAM (DRAM-PIM) has emerged as a promising technology for accelerating memory-intensive operations in modern applications, such as Large Language Models (LLMs). Despite its potential, current software stacks for DRAM-PIM face…

Hardware Architecture · Computer Science 2025-06-03 Yongwon Shin , Dookyung Kang , Hyojin Sung

The Exact Circular Pattern Matching (ECPM) problem consists of reporting every occurrence of a rotation of a pattern $P$ in a text $T$. In many real-world applications, specifically in computational biology, circular rotations are of…

Data Structures and Algorithms · Computer Science 2022-04-21 Will Solow , Matthew Barich , Brendan Mumey
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